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How to get fromUniversity of Chicago to Philadelphiaby plane, bus (Flixbus, Greyhound), train (Amtrak), car, train, bus, or bus (Greyhound)

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There are 11 ways to get from University of Chicago to Philadelphia by plane, bus (Flixbus, Greyhound), train (Amtrak), car, train, bus, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Chicago Midway International Airport to Philadelphia International Airport

    best
    1. Fly from Chicago Midway International Airport (MDW) to Philadelphia International Airport (PHL)plane plane MDW - PHL
    4h 46m
    $146–376

  2. Fly Chicago O'Hare International Airport to Lancaster, drive

    cheapest
    1. Fly from Chicago O'Hare International Airport (ORD) to Lancaster (LNS)plane plane ORD - LNS
    2. Drive from Lancaster-Airport-LNS to Philadelphiacar car
    5h 58m
    $83–389

  3. Bus

    1. Take the bus from Chicago to Harrisburg Bus Stationbus bus FlixBus N2640
    2. Take the bus from Harrisburg Bus Station to Philadelphia Bus Stationbus bus Greyhound US0421 / ...
    20h 49m
    $138–238

  4. Train via Washington (Amtrak)

    1. Take the train from Chicago Union Station to Rockville Amtraktrain train Floridian
    2. Take the train from Washington Union Station to 30th Street Stationtrain train Acela
    21h 5m
    $288–600

  5. Drive 750.9 mi

    1. Drive from University of Chicago to Philadelphiacar car 750.9 mi
    12h 19m
    $137–198

  6. Train to Chicago O'Hare International Airport, fly to Philadelphia International Airport

    1. Take the train from 55th - 56th - 57th St. to Van Buren St.train train
    2. Fly from Chicago O'Hare International Airport (ORD) to Philadelphia International Airport (PHL)plane plane ORD - PHL
    5h 18m
    $128–232

  7. Fly Chicago Midway International Airport to Baltimore-Washington International Airport, train

    1. Fly from Chicago Midway International Airport (MDW) to Baltimore-Washington International Airport (BWI)plane plane MDW - BWI
    2. Take the train from BWI Thurgood Marshall to 30th Street Stationtrain train
    6h 8m
    $146–954

  8. Fly Chicago Midway International Airport to Ronald Reagan Washington National Airport, train

    1. Fly from Chicago Midway International Airport (MDW) to Ronald Reagan Washington National Airport (DCA)plane plane MDW - DCA
    2. Take the train from Washington Union Station to 30th Street Stationtrain train
    6h 13m
    $166–800

  9. Fly Chicago O'Hare International Airport to Lehigh Valley International Airport, bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Lehigh Valley International Airport (ABE)plane plane ORD - ABE
    2. Take the bus from Lehigh Valley International Airport to Philadelphia Bus Stationbus bus
    8h 4m
    $84–397

  10. Bus via Baltimore

    1. Take the bus from Chicago Bus Station to Baltimore Downtown Bus Stationbus bus Greyhound US0164
    2. Take the bus from Baltimore to Philadelphiabus bus Ppb 3613 / ...
    23h 25m
    $138–286

  11. Train (Amtrak)

    1. Take the train from Chicago Union Station to 30th Street Stationtrain train Cardinal
    28h 4m
    $336–706

University of Chicago to Philadelphia by foot and bus

Calendar12Weekly Services
Duration20h 49mAverage Duration
Ticket$138Cheapest Price
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Questions & Answers

Map of how to get from University of Chicago to Philadelphia.ExpandLaunch map view
  • Distance: 694.7 mi
  • Duration: 4h 46m

What companies run services between University of Chicago, IL, USA and Philadelphia, PA, USA?

Southwest Airlines flies from Chicago Midway International Airport (MDW) to Philadelphia International Airport (PHL) 5 times a day. Alternatively, you can take a vehicle from University of Chicago to Philadelphia Bus Station via Cottage Grove & 58th Street, 95th Red Line Station, Chicago, and Harrisburg Bus Station in around 20h 49m.

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