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How to get fromUpper East Side to Buffaloby subway, train, plane, bus, car, or bus (Flixbus)

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There are 9 ways to get from Upper East Side to Buffalo by subway, train, plane, bus, car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Line 6 subway, train to John F. Kennedy International Airport, fly to Buffalo Niagara International Airport

    best
    1. Take the subway from 86th Street to Grand Central-42 Stsubway subway
    2. Take the train from Grand Central Terminal to Jamaicatrain train
    3. Fly from John F. Kennedy International Airport (JFK) to Buffalo Niagara International Airport (BUF)plane plane JFK - BUF
    4h 4m
    $94–530

  2. Bus

    cheapest
    1. Take the bus from New York to Buffalobus bus Adt N816 / ...
    9h 13m
    $63–283

  3. Train

    1. Take the train from New York Penn Station to Buffalotrain train VIA Rail
    9h 42m
    $113–293

  4. Drive 360.7 mi

    1. Drive from Upper East Side to Buffalocar car 360.7 mi
    7h 20m
    $66–96

  5. Bus to Laguardia Airport, fly to Buffalo Niagara International Airport

    1. Take the bus from E 125 St/Lexington Av to Laguardia Rd/94 Stbus bus
    2. Fly from Laguardia Airport (LGA) to Buffalo Niagara International Airport (BUF)plane plane LGA - BUF
    4h 5m
    $103–690

  6. Subway, train to Newark Liberty International Airport, fly to Buffalo Niagara International Airport

    1. Take the subway from 86th Street to 34 St-Herald Sqsubway subway
    2. Take the train from New York Penn Station to Newark Airport Railroad Stationtrain train
    3. Fly from Newark Liberty International Airport (EWR) to Buffalo Niagara International Airport (BUF)plane plane EWR - BUF
    4h 21m
    $100–550

  7. Fly Laguardia Airport to Rochester, bus

    1. Fly from Laguardia Airport (LGA) to Rochester (ROC)plane plane LGA - ROC
    2. Take the bus from Rochester Bus Stop to Buffalobus bus
    5h 44m
    $125–656

  8. Fly Newark Liberty International Airport to Rochester, bus

    1. Fly from Newark Liberty International Airport (EWR) to Rochester (ROC)plane plane EWR - ROC
    2. Take the bus from Rochester Bus Stop to Buffalobus bus
    6h
    $522–1,676

  9. Bus via New York Midtown (Flixbus)

    1. Take the bus from New York Midtown to Buffalobus bus FlixBus N2686 / ...
    9h 45m
    $73–123

Upper East Side to Buffalo by subway, foot, and bus

Calendar45Weekly Services
Duration9h 13mAverage Duration
Ticket$63Cheapest Price
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Questions & Answers

Map of how to get from Upper East Side to Buffalo.ExpandLaunch map view
  • Distance: 332.6 mi
  • Duration: 4h 4m

What companies run services between Upper East Side, NY, USA and Buffalo, NY, USA?

Trailways operates a bus from New York to Buffalo every 4 hours. Tickets cost $60–280 and the journey takes 8h. Alternatively, VIA Rail operates a train from New York Penn Station to Buffalo once daily. Tickets cost $110–290 and the journey takes 8h 24m.

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Bus operators

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