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How to get fromUrbana to Knoxvilleby plane, bus (Greyhound), train, bus, car, or bus (Flixbus)

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There are 6 ways to get from Urbana to Knoxville by plane, bus (Greyhound), train, bus, car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from University Of Illinois Willard Airport (CMI) to Mcghee Tyson Airport (TYS)plane plane CMI - TYS
    4h 55m
    $207–846

  2. Drive 464.5 mi

    cheapest
    1. Drive from Urbana to Knoxvillecar car 464.5 mi
    8h 1m
    $85–123

  3. Bus

    1. Take the bus from Champaign Intermodal Trans Ctr to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis Union Station to Port Authority Bus Terminalbus bus
    3. Take the bus from New York to Knoxvillebus bus Nyc
    37h 43m
    $321–519

  4. Train, bus

    1. Take the train from Champaign-Urbana to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Croton-Harmon Amtrak Stationtrain train
    3. Take the train from Croton-Harmon to 125th Street - Harlemtrain train
    4. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    39h 9m
    $469–916

  5. Bus via Auburn Gresham

    1. Take the bus from Champaign Intermodal Trans Ctr to Chicagobus bus
    2. Take the bus from Chicago to New York Midtownbus bus
    3. Take the bus from New York to Knoxvillebus bus Nyc
    38h 1m
    $353–539

  6. Bus, train

    1. Take the bus from Champaign Intermodal Trans Ctr to Indianapolis Union Stationbus bus
    2. Take the train from Indianapolis to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the bus from New York to Knoxvillebus bus Nyc
    40h 9m
    $491–939

University Of Illinois Willard Airport (CMI) to Mcghee Tyson Airport (TYS) flights

Calendar36Weekly Planes
Duration5h 55mAverage Duration
Ticket$133Cheapest Price
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Questions & Answers

Map of how to get from Urbana to Knoxville.ExpandLaunch map view
  • Distance: 394 mi
  • Duration: 4h 55m

What companies run services between Urbana, IL, USA and Knoxville, TN, USA?

American Airlines and United Airlines fly from University Of Illinois Willard Airport (CMI) to Mcghee Tyson Airport (TYS) 5 times a day. Alternatively, you can take a bus from Green & Race to Knoxville via Illinois Terminal, Champaign Intermodal Trans Ctr, Indianapolis Union Station, Port Authority Bus Terminal, 34 St-Herald Sq, East Broadway, New York, and Knoxville in around 37h 43m.

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