There are 5 ways to get from Uyuni to Santiago by plane, bus, car, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Uyuni Airport
best- Fly from Uyuni Airport (UYU) to Comodoro Arturo Merino Benítez International Airport (SCL)plane UYU - SCL
14h 46m$257–810Bus to Calama Airport, fly
cheapest- Take the bus from Uyuni to Terminal de Buses Calamabus
- Fly from Calama Airport (CJC) to Comodoro Arturo Merino Benítez International Airport (SCL)plane CJC - SCL
10h 18m$100–249Bus
- Take the bus from Uyuni to Terminal de Buses Calamabus Uyuni
- Take the bus from Terminal de Buses Calama to Terminal San Borjabus Calama
27h 44m$103–143Drive 1,921.9 km
- Drive from Uyuni to Santiagocar 1,921.9 km
23h 51m$270–390Bus via Calama
- Take the bus from Uyuni to Terminal Rodoviario Calamabus Calama
- Take the bus from Calama to Santiagobus FlixBus CL072A / ...
30h 55m$185–265
Uyuni to Santiago by bus
Comparing Your Travel Options
The cheapest way to get from Uyuni to Santiago is to bus which costs $100 - $150 and takes 27h 44m.
The fastest way to get from Uyuni to Santiago is to bus and fly which takes 10h 18m and costs $100 - $250.
No, there is no direct bus from Uyuni to Santiago. However, there are services departing from Uyuni and arriving at Terminal San Borja via Terminal de Buses Calama. The journey, including transfers, takes approximately 27h 44m.
The distance between Uyuni and Santiago is 1506 km. The road distance is 1921.9 km.
The best way to get from Uyuni to Santiago without a car is to bus which takes 27h 44m and costs $100 - $150.
It takes approximately 14h 46m to get from Uyuni to Santiago, including transfers.
Uyuni to Santiago bus services, operated by Cruz del Norte Turismo Internacional, depart from Uyuni station.
The best way to get from Uyuni to Santiago is to fly which takes 14h 46m and costs $250 - $850. Alternatively, you can bus, which costs $100 - $150 and takes 27h 44m.
Uyuni to Santiago bus services, operated by Cruz del Norte Turismo Internacional, arrive at Terminal de Buses Calama station.
Santiago is 1h ahead of Uyuni. It is currently 5:14 PM in Uyuni and 6:14 PM in Santiago.
What companies run services between Uyuni, Potosí, Bolivia and Santiago, Chile?
Boliviana de Aviación flies from Uyuni Airport (UYU) to Comodoro Arturo Merino Benítez International Airport (SCL) twice a week. Alternatively, you can take a bus from Uyuni to Terminal San Borja via Terminal de Buses Calama in around 27h 44m.
- Website
- latam.com
Flights from Calama Airport to Comodoro Arturo Merino Benítez International Airport
- Ave. Duration
- 2h 4m
- When
- Every day
- Estimated price
- $50–220
- Website
- jetsmart.com
Flights from Calama Airport to Comodoro Arturo Merino Benítez International Airport
- Ave. Duration
- 2h 7m
- When
- Every day
- Estimated price
- $30–110
- Website
- skyairline.com
Flights from Calama Airport to Comodoro Arturo Merino Benítez International Airport
- Ave. Duration
- 2h 5m
- When
- Every day
- Estimated price
- $20–160
- Website
- boa.bo
Flights from Uyuni Airport to Comodoro Arturo Merino Benítez International Airport via La Paz, Santa Cruz
- Ave. Duration
- 14h 20m
- When
- Tuesday
- Estimated price
- $250–700
Flights from Uyuni Airport to Comodoro Arturo Merino Benítez International Airport via La Paz, Cochabamba, Santa Cruz
- Ave. Duration
- 14h 20m
- When
- Tuesday
- Estimated price
- $250–700
- Phone
- +56 9 8149 3691
- [email protected]
Bus from Uyuni to Terminal de Buses Calama
- Ave. Duration
- 5h 29m
- Frequency
- 4 times a week
- Estimated price
- $55–80
- Book at
- ticketsbolivia.com
- Road
- $55–80
Bus from Uyuni to Terminal de Buses Calama
- Ave. Duration
- 5h 29m
- Frequency
- 4 times a week
- Estimated price
- $55–80
- Book at
- ticketsbolivia.com
- Road
- $55–80
- [email protected]
- Website
- ciktur.cl
Bus from Terminal de Buses Calama to Terminal San Borja
- Ave. Duration
- 21h 15m
- Frequency
- Every 4 hours
- Estimated price
- $48–65
- Schedules at
- kupos.cl
- Cama
- $55–65
- Semi Cama
- $50–65
- Phone
- +𝟱𝟲 𝟵 𝟲𝟲𝟱𝟭 𝟮𝟯𝟱𝟮
- Website
- Ticket Bolivia
Bus from Uyuni to Terminal Rodoviario Calama
- Ave. Duration
- 7h
- Frequency
- 3 times a day
- Estimated price
- $26
- Website
- Ticket Bolivia
- Website
- Flixbus Chile
Bus from Calama to Santiago
- Ave. Duration
- 22h 55m
- Frequency
- 3 times a day
- Estimated price
- $160–240
- Schedules at
- Flixbus Chile
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Booking & Getting There
Yes, the driving distance between Uyuni to Santiago is 1922 km. It takes approximately 23h 51m to drive from Uyuni to Santiago.
Book your Uyuni to Santiago bus tickets online with 12go.asia.
There are 3331+ hotels available in Santiago.













