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How to get fromVan Nuys to Chicagoby plane, train (Amtrak), bus (Greyhound, Flixbus), car, or train

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There are 9 ways to get from Van Nuys to Chicago by plane, train (Amtrak), bus (Greyhound, Flixbus), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Burbank Bob Hope Airport to Chicago Midway International Airport

    best
    1. Fly from Burbank Bob Hope Airport (BUR) to Chicago Midway International Airport (MDW)plane plane BUR - MDW
    5h 52m
    $118–503
  2. Fly Los Angeles International Airport to Chicago O'Hare International Airport

    cheapest
    1. Fly from Los Angeles International Airport (LAX) to Chicago O'Hare International Airport (ORD)plane plane LAX - ORD
    6h 39m
    $110–378
  3. Train (Amtrak)

    1. Take the train from Van Nuys to Fullerton Amtrak Stationtrain train Pacific Surfliner
    2. Take the train from Fullerton Amtrak Station to Chicago Union Stationtrain train Southwest Chief
    45h 13m
    $1,224–1,937
  4. Bus

    1. Take the bus from Los Angeles Union Station to St Louis Bus Stationbus bus Greyhound US1210
    2. Take the bus from St Louis Bus Station to Chicago Bus Stationbus bus FlixBus N2521 / ...
    2d 1h
    $398–586
  5. Drive  2,023.3 mi

    1. Drive from Van Nuys to Chicagocar car 2,023.3 mi
    31h 48m
    $370–534
  6. Fly Los Angeles International Airport to Chicago Midway International Airport

    1. Fly from Los Angeles International Airport (LAX) to Chicago Midway International Airport (MDW)plane plane LAX - MDW
    6h 21m
    $140–618
  7. Fly Long Beach Airport to Chicago Midway International Airport

    1. Fly from Long Beach Airport (LGB) to Chicago Midway International Airport (MDW)plane plane LGB - MDW
    8h 39m
    $172–765
  8. Train to Ontario International Airport, fly to Chicago Midway International Airport

    1. Take the train from L.A. Union Station to Rancho Cucamongatrain train
    2. Fly from Ontario International Airport (ONT) to Chicago Midway International Airport (MDW)plane plane ONT - MDW
    9h 30m
    $136–573
  9. Train to John Wayne Airport Orange County, fly to Chicago O'Hare International Airport

    1. Take the train from Van Nuys to Fullerton Amtrak Stationtrain train
    2. Fly from John Wayne Airport Orange County (SNA) to Chicago O'Hare International Airport (ORD)plane plane SNA - ORD
    10h 2m
    $120–456

Van Nuys to Chicago by train (Amtrak)

Calendar7Weekly Trains
Duration45h 13mAverage Duration
Ticket$1,224Cheapest Price
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Comparing Your Travel Options

What companies run services between Van Nuys, CA, USA and Chicago, IL, USA?

Southwest Airlines flies from Burbank Bob Hope Airport (BUR) to Chicago Midway International Airport (MDW) every 4 hours. Alternatively, you can take a train from Van Nuys to Chicago Union Station via Fullerton Amtrak Station in around 45h 13m.

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