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How to get fromVan Nuys to Santa Fe Depotby train (Amtrak), bus, car, plane, or bus (Amtrak)

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There are 6 ways to get from Van Nuys to Santa Fe Depot by train (Amtrak), bus, car, plane, or bus (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from Van Nuys to San Diegotrain train Pacific Surfliner
    3h 54m
    $45–100

  2. Drive 135.9 mi

    cheapest
    1. Drive from Van Nuys to Santa Fe Depotcar car 135.9 mi
    2h 27m
    $25–36

  3. Bus

    1. Take the bus from Van Nuys FlyAway Terminal - 7610 Woodley Ave to LAX Tom Bradley International Terminalbus bus Van Nuys
    2. Take the bus from LAX Terminal 3 Shared Rides Stop to San Diegobus bus reLAXsan
    4h 38m
    $63–123

  4. Fly from Los Angeles International Airport

    1. Fly from Los Angeles International Airport (LAX) to San Diego International Airport (SAN)plane plane LAX - SAN
    3h 20m
    $170–668

  5. Bus via Union Station - Metro B & D Lines (Amtrak)

    1. Take the bus from Los Angeles to San Diegobus bus Amtrak Thruway Connecting Service
    4h 58m
    $44–69

  6. Fly from Burbank Bob Hope Airport

    1. Fly from Burbank Bob Hope Airport (BUR) to San Diego International Airport (SAN)plane plane BUR - SAN
    5h 5m
    $268–663

Van Nuys to Santa Fe Depot by train (Amtrak)

Calendar42Weekly Trains
Duration3h 54mAverage Duration
Ticket$45Cheapest Price
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Questions & Answers

Map of how to get from Van Nuys to Santa Fe Depot.ExpandLaunch map view
  • Distance: 145.5 mi
  • Duration: 3h 54m

What companies run services between Van Nuys, CA, USA and Santa Fe Depot, San Diego County, CA, USA?

Amtrak operates a train from Van Nuys to San Diego every 4 hours. Tickets cost $45–100 and the journey takes 3h 54m. Alternatively, you can take a bus from Van Nuys FlyAway Terminal - 7610 Woodley Ave to Santa Fe Depot via LAX Tom Bradley International Terminal, LAX Terminal 3 Shared Rides Stop, San Diego, and Old Town Station in around 4h 38m.

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