There are 8 ways to get from Vero Beach to Des Moines by taxi, plane, bus (Greyhound, Flixbus), bus, train, car, or shuttle
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Taxi to Melbourne International Airport, fly
best- Take the taxi from Vero Beach to Melbourne International Airport (MLB)taxi
- Fly from Melbourne International Airport (MLB) to Des Moines (DSM)plane MLB - DSM
5h 53m$237–644Drive to Orlando Sanford, fly
cheapest- Drive from Vero Beach to Orlando-Sanford-Airport-SFBcar
- Fly from Orlando Sanford (SFB) to Des Moines (DSM)plane SFB - DSM
5h 15m$132–520Bus
- Take the bus from Vero Beach to Port St Luciebus
- Take the bus from Port St Lucie to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Indianapolis Union Stationbus
- Take the bus from Indianapolis Union Station to Des Moinesbus
36h 4m$306–465Bus, train
- Take the bus from Fort Pierce to Orlando - RedCoach Station, FLbus
- Take the train from Orlando to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain
- Take the bus from Galesburg to Des Moinesbus
2d 4h$1,112–1,819Drive 1,414.5 mi
- Drive from Vero Beach to Des Moinescar 1,414.5 mi
24h 27m$242–350Fly from Vero Beach Municipal Airport
- Fly from Vero Beach Municipal Airport (VRB) to Des Moines (DSM)plane VRB - DSM
10h 4m$144–592Shuttle to Orlando, fly
- Take a shuttle bus from Vero Beach, FL - Vero Beach Outlets to Orlando Airport
- Fly from Orlando (MCO) to Des Moines (DSM)plane MCO - DSM
6h 9m$208–594Shuttle, train, bus
- Take a shuttle bus from Vero Beach, FL - Vero Beach Outlets to Orlando Airport
- Take the train from Kissimmee Amtrak Station to Chicago Union Stationtrain
- Take the bus from Chicago Bus Station to Des Moinesbus
2d 5h$1,117–1,723
Melbourne International Airport (MLB) to Des Moines (DSM) flights
Comparing Your Travel Options
The cheapest way to get from Vero Beach to Des Moines is to drive which costs $240 - $350 and takes 24h 27m.
The fastest way to get from Vero Beach to Des Moines is to drive and fly which takes 5h 15m and costs $130 - $550.
No, there is no direct bus from Vero Beach to Des Moines. However, there are services departing from Vero Beach and arriving at Des Moines via Port St Lucie, Atlanta Bus Station and Indianapolis Union Station. The journey, including transfers, takes approximately 36h 4m.
The distance between Vero Beach and Des Moines is 1233 miles. The road distance is 1422.8 miles.
The best way to get from Vero Beach to Des Moines without a car is to bus which takes 36h 4m and costs $300 - $470.
It takes approximately 5h 53m to get from Vero Beach to Des Moines, including transfers.
Vero Beach to Des Moines bus services, operated by Greyhound USA, depart from Vero Beach station.
The best way to get from Vero Beach to Des Moines is to bus which takes 36h 4m and costs $300 - $470. Alternatively, you can fly, which costs $140 - $600 and takes 10h 4m.
Vero Beach to Des Moines bus services, operated by Greyhound USA, arrive at Port St Lucie station.
Des Moines is 1h behind Vero Beach. It is currently 8:22 PM in Vero Beach and 7:22 PM in Des Moines.
What companies run services between Vero Beach, FL, USA and Des Moines, IA, USA?
You can take a vehicle from Vero Beach to Des Moines via Vero Beach, Port St Lucie, Atlanta Bus Station, and Indianapolis Union Station in around 36h 4m. Alternatively, American Airlines, Breeze Airways, and Delta fly from Vero Beach Municipal Airport (VRB) to Des Moines (DSM) once daily.
- Website
- delta.com
Flights from Melbourne International Airport to Des Moines via Atlanta
- Ave. Duration
- 7h 22m
- When
- Every day
- Estimated price
- $100–480
Flights from Vero Beach Municipal Airport to Des Moines via Pittsburgh, Detroit
- Ave. Duration
- 9h 49m
- When
- Thursday and Sunday
- Estimated price
- $180–1,000
Flights from Orlando to Des Moines via Atlanta
- Ave. Duration
- 5h 3m
- When
- Every day
- Estimated price
- $90–450
- Website
- aa.com
Flights from Melbourne International Airport to Des Moines via Charlotte
- Ave. Duration
- 6h 17m
- When
- Thursday, Friday, and Sunday
- Estimated price
- $100–500
Flights from Vero Beach Municipal Airport to Des Moines via Charlotte
- Ave. Duration
- 10h 50m
- When
- Every day
- Estimated price
- $110–550
Flights from Orlando to Des Moines via Charlotte
- Ave. Duration
- 5h 20m
- When
- Monday, Tuesday, Wednesday, and Saturday
- Estimated price
- $100–470
- Website
- southwest.com
Flights from Orlando to Des Moines
- Ave. Duration
- 3h 10m
- When
- Saturday
- Estimated price
- $90–450
Flights from Orlando to Des Moines via Nashville
- Ave. Duration
- 5h 5m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $90–450
Flights from Orlando to Des Moines via Chicago Midway
- Ave. Duration
- 5h 26m
- When
- Sunday and Saturday
- Estimated price
- $100–470
- Website
- allegiantair.com
Flights from Orlando Sanford to Des Moines
- Ave. Duration
- 2h 56m
- When
- Friday, Wednesday, Saturday, and Monday
- Estimated price
- $95–470
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Orlando to Chicago Union Station
- Ave. Duration
- 38h 55m
- Frequency
- Once daily
- Estimated price
- $900–1,500
- Website
- Amtrak
Train from Chicago Union Station to Galesburg Amtrak Station
- Ave. Duration
- 2h 36m
- Frequency
- 4 times a day
- Estimated price
- $85–140
- Website
- Amtrak
Train from Kissimmee Amtrak Station to Chicago Union Station
- Ave. Duration
- 39h 35m
- Frequency
- Once daily
- Estimated price
- $950–1,500
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Vero Beach to Port St Lucie
- Ave. Duration
- 1h 5m
- Frequency
- Once daily
- Estimated price
- $6–9
- Website
- Greyhound
Bus from Atlanta Bus Station to Indianapolis Union Station
- Ave. Duration
- 11h 50m
- Frequency
- Every 4 hours
- Estimated price
- $100–150
- Website
- Greyhound
Bus from Indianapolis Union Station to Des Moines
- Ave. Duration
- 9h 50m
- Frequency
- Twice daily
- Estimated price
- $85–130
- Website
- Greyhound
Bus from Galesburg to Des Moines
- Ave. Duration
- 4h 55m
- Frequency
- Twice daily
- Estimated price
- $35–60
- Website
- Greyhound
Bus from Chicago Bus Station to Des Moines
- Ave. Duration
- 8h 25m
- Frequency
- 5 times a day
- Estimated price
- $65–100
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Port St Lucie to Atlanta Bus Station
- Ave. Duration
- 10h 10m
- Frequency
- Twice daily
- Estimated price
- $85–140
- Schedules at
- Flixbus USA
- Phone
- +1 877 733 0724
- Website
- RedCoach
Bus from Fort Pierce to Orlando - RedCoach Station, FL
- Ave. Duration
- 1h 45m
- Frequency
- 4 times a day
- Estimated price
- $26–40
- Website
- RedCoach
- Phone
- +1 772-343-0217
- Website
- Smart Shuttle Line, Inc.
Shuttle from Vero Beach, FL - Vero Beach Outlets to Orlando Airport
- Ave. Duration
- 1h 35m
- Frequency
- 4 times a day
- Estimated price
- $65–80
- Schedules at
- Smart Shuttle Line, Inc.
- one passenger
- $65–80
Shuttle from Vero Beach, FL - Vero Beach Outlets to Orlando Airport
- Ave. Duration
- 1h 35m
- Frequency
- 4 times a day
- Estimated price
- $65–80
- Schedules at
- Smart Shuttle Line, Inc.
- one passenger
- $65–80
- Ave. Duration
- 51 min
- Estimated price
- $110–150
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Booking & Getting There
Yes, the driving distance between Vero Beach to Des Moines is 1423 miles. It takes approximately 24h 27m to drive from Vero Beach to Des Moines.
Book your Vero Beach to Des Moines bus tickets online with Omio.
There are 241+ hotels available in Des Moines.










