There are 6 ways to get from Vicenza to Siena by train (Trenitalia), bus, train, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train
best- Take the train from Padova to Firenze S.M.N.train Fr
- Take the train from Firenze S.M.N. to Sienatrain Re
4h 30m€40–152Bus
cheapest- Take the bus from Padua to Sienabus 541
6h 8m€28–41Bus, train
- Take the bus from Vicenza Museo to Padova Stationbus
- Take the train from Padova to Firenze S.M.N.train Fr
- Take the bus from Firenze Autostazione to Siena-Via Tozzibus 131
4h 38m€35–62Drive 302.1 km
- Drive from Vicenza to Sienacar 302.1 km
3h 19m€49–71Train to Verona Villafranca Airport, fly, train
- Take the train from Vicenza to Verona Porta Nuovatrain
- Fly from Verona Villafranca Airport (VRN) to Florence Peretola Airport (FLR)plane VRN - FLR
- Take the train from Firenze S.M.N. to Sienatrain
8h 8m€110–375Train to Venice Marco Polo Airport, fly, train
- Take the train from Vicenza to Venezia Mestretrain
- Fly from Venice Marco Polo Airport (VCE) to Florence Peretola Airport (FLR)plane VCE - FLR
- Take the train from Firenze S.M.N. to Sienatrain
7h 24m€113–255
Vicenza to Siena by train
Comparing Your Travel Options
The cheapest way to get from Vicenza to Siena is to bus which costs €27 - €45 and takes 6h 8m.
The fastest way to get from Vicenza to Siena is to drive which takes 3h 19m and costs €45 - €75.
No, there is no direct bus from Vicenza to Siena. However, there are services departing from Vicenza Museo and arriving at Siena via Padua. The journey, including transfers, takes approximately 6h 8m.
No, there is no direct train from Vicenza to Siena. However, there are services departing from Vicenza and arriving at Siena via Padova and Firenze S.M.N.. The journey, including transfers, takes approximately 4h 30m.
The distance between Vicenza and Siena is 337 km. The road distance is 302.1 km.
The best way to get from Vicenza to Siena without a car is to train which takes 4h 30m and costs €35 - €160.
It takes approximately 4h 30m to get from Vicenza to Siena, including transfers.
Vicenza to Siena bus services, operated by FlixBus, depart from Padua station.
Vicenza to Siena train services, operated by Trenitalia Frecce, depart from Padova station.
The best way to get from Vicenza to Siena is to train which takes 4h 30m and costs €35 - €160. Alternatively, you can bus, which costs €27 - €45 and takes 6h 8m.
What companies run services between Vicenza, Italy and Siena, Italy?
You can take a train from Vicenza to Siena via Padova and Firenze S.M.N. in around 4h 30m. Alternatively, FlixBus operates a bus from Padua to Siena 5 times a week. Tickets cost €23–35 and the journey takes 4h 5m.
- Website
- ita-airways.com
Flights from Verona Villafranca Airport to Florence Peretola Airport via Frankfurt
- Ave. Duration
- 5h 7m
- When
- Every day
- Estimated price
- €200–700
Flights from Verona Villafranca Airport to Florence Peretola Airport via Rome
- Ave. Duration
- 4h 30m
- When
- Tuesday, Wednesday, Thursday, Saturday, and Sunday
- Estimated price
- €85–650
Flights from Verona Villafranca Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 6h 27m
- When
- Every day
- Estimated price
- €180–650
Flights from Venice Marco Polo Airport to Florence Peretola Airport via Rome
- Ave. Duration
- 3h 35m
- When
- Every day
- Estimated price
- €140–200
Flights from Venice Marco Polo Airport to Florence Peretola Airport via Zurich
- Ave. Duration
- 3h 41m
- When
- Every day
- Estimated price
- €85–330
Flights from Venice Marco Polo Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 4h 40m
- When
- Every day
- Estimated price
- €150–550
Flights from Venice Marco Polo Airport to Florence Peretola Airport via Vienna
- Ave. Duration
- 3h 15m
- When
- Monday, Tuesday, Thursday, and Saturday
- Estimated price
- €90–350
- Website
- airdolomiti.it
Flights from Verona Villafranca Airport to Florence Peretola Airport via Frankfurt
- Ave. Duration
- 5h 7m
- When
- Every day
- Estimated price
- €200–700
Flights from Verona Villafranca Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 6h 27m
- When
- Every day
- Estimated price
- €180–650
Flights from Venice Marco Polo Airport to Florence Peretola Airport via Munich
- Ave. Duration
- 4h 40m
- When
- Every day
- Estimated price
- €150–550
- Website
- swiss.com
Flights from Verona Villafranca Airport to Florence Peretola Airport via Rome
- Ave. Duration
- 4h 40m
- When
- Saturday
- Estimated price
- €180–650
Flights from Venice Marco Polo Airport to Florence Peretola Airport via Rome
- Ave. Duration
- 3h 40m
- When
- Every day
- Estimated price
- €140–200
Flights from Venice Marco Polo Airport to Florence Peretola Airport via Zurich
- Ave. Duration
- 3h 41m
- When
- Every day
- Estimated price
- €85–330
- Website
- austrian.com
Flights from Verona Villafranca Airport to Florence Peretola Airport via Rome
- Ave. Duration
- 4h 40m
- When
- Saturday
- Estimated price
- €180–650
Flights from Venice Marco Polo Airport to Florence Peretola Airport via Vienna
- Ave. Duration
- 3h 15m
- When
- Monday, Tuesday, Thursday, and Saturday
- Estimated price
- €90–350
Flights from Venice Marco Polo Airport to Florence Peretola Airport via Rome
- Ave. Duration
- 3h 55m
- When
- Every day
- Estimated price
- €140–200
- Phone
- +39 06 5210550
- Website
- Trenitalia Frecce
Train from Padova to Firenze S.M.N.
- Ave. Duration
- 1h 43m
- Frequency
- Hourly
- Estimated price
- €29–50
- Website
- Trenitalia Frecce
Train from Padova to Firenze S.M.N.
- Ave. Duration
- 1h 43m
- Frequency
- Hourly
- Estimated price
- €29–50
- Website
- Trenitalia Frecce
Train from Vicenza to Verona Porta Nuova
- Ave. Duration
- 26 min
- Frequency
- Hourly
- Estimated price
- €7–12
- Website
- Trenitalia Frecce
Train from Vicenza to Venezia Mestre
- Ave. Duration
- 33 min
- Frequency
- Hourly
- Estimated price
- €8–14
- Website
- Trenitalia Frecce
- Phone
- +39 06 8937 1892
- Website
- Italo Treno
Train from Padova to Firenze S.M.N.
- Ave. Duration
- 1h 53m
- Frequency
- Once daily
- Estimated price
- €25–45
- Website
- Italo Treno
Train from Padova to Firenze S.M.N.
- Ave. Duration
- 1h 53m
- Frequency
- Once daily
- Estimated price
- €25–45
- Website
- Italo Treno
Train from Vicenza to Verona Porta Nuova
- Ave. Duration
- 26 min
- Frequency
- Every 4 hours
- Estimated price
- €6–10
- Website
- Italo Treno
Train from Vicenza to Venezia Mestre
- Ave. Duration
- 34 min
- Frequency
- Every 4 hours
- Estimated price
- €7–12
- Website
- Italo Treno
- Phone
- +39.06.5210550
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Vicenza to Verona Porta Nuova
- Ave. Duration
- 1h 8m
- Frequency
- Every 20 minutes
- Estimated price
- €6–9
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
Train from Vicenza to Venezia Mestre
- Ave. Duration
- 1h 2m
- Frequency
- Every 20 minutes
- Estimated price
- €7–10
- Website
- Trenitalia
Train from Firenze S.M.N. to Siena
- Ave. Duration
- 1h 30m
- Frequency
- Hourly
- Estimated price
- €11–16
- Website
- Trenitalia
- Phone
- +39 06 68475475
- [email protected]
- Website
- Trenitalia Eurocity
Train from Vicenza to Verona Porta Nuova
- Ave. Duration
- 26 min
- Frequency
- 3 times a day
- Estimated price
- €19–60
- Website
- Trenitalia Eurocity
- 1st Class
- €40–60
- 2nd Class
- €19–26
- Phone
- +39 049 8241199
- [email protected]
- Website
- fsbusitalia.it
Bus from Vicenza Museo to Padova Station
- Ave. Duration
- 54 min
- Frequency
- Hourly
- Estimated price
- €4–6
- Schedules at
- fsbusitalia.it
- Phone
- +39 800 142 424
- [email protected]
- Website
- at-bus.it
Bus from Firenze Autostazione to Siena-Via Tozzi
- Ave. Duration
- 1h 15m
- Frequency
- Hourly
- Estimated price
- €5–6
- Schedules at
- at-bus.it
Rome2Rio's guide to FlixBus
Contact DetailsContact Details
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Padua to Siena
- Ave. Duration
- 4h 5m
- Frequency
- 5 times a week
- Estimated price
- €23–35
- Website
- Flixbus
Want to know more about travelling around Italy
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Italy Travel Guides
Read the travel guide
5 incredible day trips from Florence by train
Read the travel guide
Want to know more about Flixbus?
Read the travel guide
Booking & Getting There
Vicenza to Siena bus services, operated by FlixBus, arrive at Siena station.
Vicenza to Siena train services, operated by Trenitalia Frecce, arrive at Firenze S.M.N. station.
Yes, the driving distance between Vicenza to Siena is 302 km. It takes approximately 3h 19m to drive from Vicenza to Siena.
Book your Vicenza to Siena train tickets online with Omio.
Book your Vicenza to Siena bus tickets online with Omio.
There are 2421+ hotels available in Siena.

























