There are 6 ways to get from Walpole to Buffalo by train, plane, bus (Greyhound), train (Amtrak), car, bus, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, fly to Buffalo Niagara International Airport
best- Take the train from Walpole to Back Baytrain
- Fly from Boston Logan Airport (BOS) to Buffalo Niagara International Airport (BUF)plane BOS - BUF
5h 10m$112–696Drive 449.1 mi
cheapest- Drive from Walpole to Buffalocar 449.1 mi
7h 55m$82–119Bus (Greyhound)
- Take the bus from Boston to Buffalobus Greyhound US0171
12h 53m$87–134Train (Amtrak)
- Take the train from Boston to Buffalo Depew Stationtrain Lake Shore Limited
14h 30m$265–569Fly to Rochester, bus
- Fly from Boston Logan Airport (BOS) to Rochester (ROC)plane BOS - ROC
- Take the bus from Rochester Bus Stop to Buffalobus
6h 35m$161–860Bus via Ithaca
- Take the bus from Boston to Ithacabus FlixBus 2691
- Take the bus from Ithaca to Buffalobus Adt N806-D / ...
14h 22m$90–139
Walpole to Buffalo by bus (Greyhound)
Comparing Your Travel Options
The cheapest way to get from Walpole to Buffalo is to drive which costs $80 - $120 and takes 7h 55m.
The fastest way to get from Walpole to Buffalo is to train and fly which takes 5h 10m and costs $110 - $700.
No, there is no direct bus from Walpole to Buffalo. However, there are services departing from Main St @ Stone St and arriving at Buffalo via Forest Hills, Nubian and Boston. The journey, including transfers, takes approximately 12h 53m.
No, there is no direct train from Walpole to Buffalo. However, there are services departing from Walpole and arriving at Buffalo via Boston and Buffalo Depew Station. The journey, including transfers, takes approximately 14h 30m.
The distance between Walpole and Buffalo is 429 miles. The road distance is 451.7 miles.
The best way to get from Walpole to Buffalo without a car is to bus which takes 12h 53m and costs $85 - $140.
It takes approximately 5h 10m to get from Walpole to Buffalo, including transfers.
Walpole to Buffalo bus services, operated by Greyhound USA, depart from Boston station.
Walpole to Buffalo train services, operated by Amtrak, depart from Boston station.
The best way to get from Walpole to Buffalo is to bus which takes 12h 53m and costs $85 - $140. Alternatively, you can train, which costs $260 - $600 and takes 14h 30m.
What companies run services between Walpole, MA, USA and Buffalo, NY, USA?
Greyhound USA operates a bus from Boston to Buffalo once daily. Tickets cost $85–130 and the journey takes 10h 5m. Alternatively, Amtrak operates a train from Boston to Buffalo Depew Station once daily. Tickets cost $260–420 and the journey takes 11h 32m.
- Website
- aa.com
Flights from Boston Logan Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 44m
- When
- Every day
- Estimated price
- $95–650
Flights from Boston Logan Airport to Buffalo Niagara International Airport via Philadelphia
- Ave. Duration
- 3h 58m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $110–700
Flights from Boston Logan Airport to Rochester
- Ave. Duration
- 1h 38m
- When
- Every day
- Estimated price
- $120–800
Flights from Boston Logan Airport to Rochester via Philadelphia
- Ave. Duration
- 4h 5m
- When
- Thursday and Friday
- Estimated price
- $150–900
- Website
- southwest.com
Flights from Boston Logan Airport to Buffalo Niagara International Airport via Baltimore
- Ave. Duration
- 3h 51m
- When
- Monday, Thursday, Friday, Sunday, Tuesday, and Wednesday
- Estimated price
- $120–700
Flights from Boston Logan Airport to Rochester via Baltimore
- Ave. Duration
- 3h 58m
- When
- Monday to Friday
- Estimated price
- $160–950
- Website
- jetblue.com
Flights from Boston Logan Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 37m
- When
- Every day
- Estimated price
- $95–650
Flights from Boston Logan Airport to Rochester via New York JFK
- Ave. Duration
- 3h 39m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $130–850
- Website
- delta.com
Flights from Boston Logan Airport to Buffalo Niagara International Airport via New York La Guardia
- Ave. Duration
- 4h
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $100–650
Flights from Boston Logan Airport to Rochester via New York La Guardia
- Ave. Duration
- 4h 1m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $130–850
- Website
- united.com
Flights from Boston Logan Airport to Rochester via Washington Dulles
- Ave. Duration
- 4h 8m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $170–950
Train from Walpole to Back Bay
- Ave. Duration
- 37 min
- Frequency
- Every 4 hours
- Estimated price
- $3–9
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $3–9
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Boston to Buffalo Depew Station
- Ave. Duration
- 11h 32m
- Frequency
- Once daily
- Estimated price
- $260–420
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Boston to Buffalo
- Ave. Duration
- 10h 5m
- Frequency
- Once daily
- Estimated price
- $85–130
- Website
- Greyhound
Bus from Rochester Bus Stop to Buffalo
- Ave. Duration
- 1h 20m
- Frequency
- 5 times a day
- Estimated price
- $13–20
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Rochester Bus Stop to Buffalo
- Ave. Duration
- 1h 30m
- Frequency
- Every 4 hours
- Estimated price
- $11–18
- Schedules at
- Flixbus USA
Bus from Boston to Ithaca
- Ave. Duration
- 7h 44m
- Frequency
- 3 times a week
- Estimated price
- $60–90
- Schedules at
- Flixbus USA
Bus from Ithaca to Buffalo
- Ave. Duration
- 3h 45m
- Frequency
- Twice daily
- Estimated price
- $26–40
- Schedules at
- Flixbus USA
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Booking & Getting There
Walpole to Buffalo bus services, operated by Greyhound USA, arrive at Buffalo station.
Walpole to Buffalo train services, operated by Amtrak, arrive at Buffalo Depew Station.
Yes, the driving distance between Walpole to Buffalo is 452 miles. It takes approximately 7h 55m to drive from Walpole to Buffalo.
There are 200+ hotels available in Buffalo.













