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How to get fromWashington DC to Florenceby train (Amtrak), bus (Greyhound, Flixbus), car, plane, bus, train, or subway

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There are 8 ways to get from Washington DC to Florence by train (Amtrak), bus (Greyhound, Flixbus), car, plane, bus, train, or subway

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from Alexandria to Florence Stationtrain train Palmetto / ...
    9h 3m
    $222–343

  2. Bus

    cheapest
    1. Take the bus from Washington Union Station to Raleigh Bus Stationbus bus Greyhound US0670 / ...
    2. Take the bus from Raleigh Bus Station to Florence Bus Stationbus bus Greyhound US0642S / ...
    9h 58m
    $69–112

  3. Drive  399 mi

    1. Drive from Washington DC to Florencecar car 399 mi
    6h 44m
    $73–106

  4. Fly Ronald Reagan Washington National Airport to Myrtle Beach, bus

    1. Fly from Ronald Reagan Washington National Airport (DCA) to Myrtle Beach (MYR)plane plane DCA - MYR
    2. Take the bus from Myrtle Beach Bus Station to Florence Bus Stationbus bus
    5h 52m
    $101–516

  5. Bus, train

    1. Take the bus from Washington Union Station to Fayetteville Bus Stationbus bus FlixBus N2471 / ...
    2. Take the train from Fayetteville Amtrak Station to Florence Stationtrain train Palmetto / ...
    10h 23m
    $97–152

  6. Subway to Washington Dulles International Airport, fly to Myrtle Beach, bus

    1. Take the subway from McPherson Square, Blue/Orange/Silver Line Track 2 Platform to Washington Dulles International Airport, Silver Line Center Platformsubway subway
    2. Fly from Washington Dulles International Airport (IAD) to Myrtle Beach (MYR)plane plane IAD - MYR
    3. Take the bus from Myrtle Beach Bus Station to Florence Bus Stationbus bus
    6h 15m
    $75–355

  7. Train to Baltimore-Washington International Airport, fly to Myrtle Beach, bus

    1. Take the train from Washington Union Station to BWI Thurgood Marshalltrain train
    2. Fly from Baltimore-Washington International Airport (BWI) to Myrtle Beach (MYR)plane plane BWI - MYR
    3. Take the bus from Myrtle Beach Bus Station to Florence Bus Stationbus bus
    6h 23m
    $327–1,234

  8. Fly Ronald Reagan Washington National Airport to Charlotte Douglas International Airport, bus

    1. Fly from Ronald Reagan Washington National Airport (DCA) to Charlotte Douglas International Airport (CLT)plane plane DCA - CLT
    2. Take the bus from Charlotte Bus Station to Camdenbus bus
    3. Take the bus from Camden to Florence Bus Stationbus bus
    8h 12m
    $139–794

Washington DC to Florence by foot, subway, and train (Amtrak)

Calendar14Weekly Services
Duration9h 3mAverage Duration
Ticket$222Cheapest Price
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Comparing Your Travel Options

Map of how to get from Washington DC to Florence.ExpandLaunch map view
  • Distance: 410.1 mi
  • Duration: 9h 3m

What companies run services between Washington DC, USA and Florence, SC, USA?

Amtrak operates a train from Alexandria to Florence Station twice daily. Tickets cost $220–340 and the journey takes 7h 29m. Alternatively, you can take a vehicle from Washington DC to Florence Bus Station via 11 St NW+F St NW, Massachusetts Av NE+1 St NE, Washington Union Station, and Raleigh Bus Station in around 9h 58m.

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