There are 5 ways to get from Washington University in St. Louis to Chicago by plane, train (Amtrak), bus (Flixbus), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Chicago Midway International Airport
best- Fly from Lambert–St. Louis International Airport (STL) to Chicago Midway International Airport (MDW)plane STL - MDW
3h 24m$60–378Bus (Flixbus)
cheapest- Take the bus from St Louis Bus Station to Chicago Bus Stationbus FlixBus 2510 / ...
7h 24m$52–88Train (Amtrak)
- Take the train from St. Louis to Chicago Union Stationtrain Lincoln Service / ...
6h 14m$92–192Drive 299.6 mi
- Drive from Washington University in St. Louis to Chicagocar 299.6 mi
5h 13m$55–79Fly to Chicago O'Hare International Airport
- Fly from Lambert–St. Louis International Airport (STL) to Chicago O'Hare International Airport (ORD)plane STL - ORD
3h 47m$274–708
Washington University in St. Louis to Chicago by foot and train (Amtrak)
Questions & Answers
The cheapest way to get from Washington University in St. Louis to Chicago is to bus which costs $50 - $90 and takes 7h 24m.
The fastest way to get from Washington University in St. Louis to Chicago is to fly which takes 3h 24m and costs $55 - $380.
No, there is no direct bus from Washington University in St. Louis station to Chicago station. However, there are services departing from St Louis Bus Station and arriving at Chicago Bus Station via . The journey, including transfers, takes approximately 7h 24m.
No, there is no direct train from Washington University in St. Louis station to Chicago station. However, there are services departing from SKINKER station and arriving at Chicago Union Station via St. Louis. The journey, including transfers, takes approximately 6h 14m.
The distance between Washington University in St. Louis and Chicago is 274 miles. The road distance is 301.3 miles.
The best way to get from Washington University in St. Louis to Chicago without a car is to train which takes 6h 14m and costs $90 - $200.
It takes approximately 3h 24m to get from Washington University in St. Louis to Chicago, including transfers.
Washington University in St. Louis to Chicago bus services, operated by Flixbus USA, depart from St Louis Bus Station.
Washington University in St. Louis to Chicago train services, operated by Amtrak, depart from St. Louis station.
The best way to get from Washington University in St. Louis to Chicago is to fly which takes 3h 24m and costs $55 - $380. Alternatively, you can train, which costs $90 - $200 and takes 6h 14m, you could also bus, which costs $50 - $90 and takes 7h 24m.
What companies run services between Washington University in St. Louis, MO, USA and Chicago, IL, USA?
Southwest Airlines flies from Lambert–St. Louis International Airport (STL) to Chicago Midway International Airport (MDW) 5 times a day. Alternatively, Amtrak operates a train from St. Louis to Chicago Union Station 5 times a day. Tickets cost $90–190 and the journey takes 4h 55m.
- Website
- southwest.com
Flights from Lambert–St. Louis International Airport to Chicago Midway International Airport
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- $55–370
- Website
- united.com
Flights from Lambert–St. Louis International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $45–310
- Website
- aa.com
Flights from Lambert–St. Louis International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 32m
- When
- Every day
- Estimated price
- $45–310
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from St. Louis to Chicago Union Station
- Ave. Duration
- 4h 55m
- Frequency
- 5 times a day
- Estimated price
- $90–190
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from St Louis Bus Station to Chicago Bus Station
- Ave. Duration
- 6h 5m
- Frequency
- Twice daily
- Estimated price
- $50–85
- Schedules at
- flixbus.com
Want to know more about travelling around United States
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More Questions & Answers
Washington University in St. Louis to Chicago bus services, operated by Flixbus USA, arrive at Chicago Bus Station.
Washington University in St. Louis to Chicago train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Washington University in St. Louis to Chicago is 301 miles. It takes approximately 5h 13m to drive from Washington University in St. Louis to Chicago.
There are 1302+ hotels available in Chicago.