There are 10 ways to get from Washington to Mayo Clinic by plane, bus (Greyhound, Flixbus), train, bus, car, or subway
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Ronald Reagan Washington National Airport to Rochester
best- Fly from Ronald Reagan Washington National Airport (DCA) to Rochester (RST)plane DCA - RST
5h 58m$153–759Subway to Washington Dulles International Airport, fly to Rochester
cheapest- Take the subway from Farragut West, Blue/Orange/Silver Line Track 2 Platform to Washington Dulles International Airport, Silver Line Center Platformsubway
- Fly from Washington Dulles International Airport (IAD) to Rochester (RST)plane IAD - RST
7h 26m$88–463Bus
- Take the bus from Washington Union Station to Chicago Bus Stationbus
- Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus
- Take the bus from Milwaukee to Rochesterbus
26h 38m$201–345Train, bus via Madison
- Take the train from Washington Union Station to Chicago Union Stationtrain
- Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus
- Take the bus from Madison to Rochesterbus
27h 54m$326–633Drive 1,033.4 mi
- Drive from Washington to Mayo Cliniccar 1,033.4 mi
17h 39m$189–273Fly Ronald Reagan Washington National Airport to Minneapolis–Saint Paul International Airport, bus
- Fly from Ronald Reagan Washington National Airport (DCA) to Minneapolis–Saint Paul International Airport (MSP)plane DCA - MSP
- Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus
5h 28m$220–1,038Train to Baltimore-Washington International Airport, fly to Rochester
- Take the train from Washington Union Station to BWI Thurgood Marshalltrain
- Fly from Baltimore-Washington International Airport (BWI) to Rochester (RST)plane BWI - RST
7h 43m$103–1,085Subway to Washington Dulles International Airport, fly to Minneapolis–Saint Paul International Airport, bus
- Take the subway from Farragut West, Blue/Orange/Silver Line Track 2 Platform to Washington Dulles International Airport, Silver Line Center Platformsubway
- Fly from Washington Dulles International Airport (IAD) to Minneapolis–Saint Paul International Airport (MSP)plane IAD - MSP
- Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus
7h 17m$164–605Train to Baltimore-Washington International Airport, fly to Minneapolis–Saint Paul International Airport, bus
- Take the train from Washington Union Station to BWI Thurgood Marshalltrain
- Fly from Baltimore-Washington International Airport (BWI) to Minneapolis–Saint Paul International Airport (MSP)plane BWI - MSP
- Take the bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochesterbus
7h 10m$194–1,497Train, bus
- Take the train from Rockville Amtrak to Chicago Union Stationtrain
- Take the train from Chicago Union Station to St. Paul-Minneapolistrain
- Take the bus from St. Paul to Rochester, MNbus
30h 1m$400–813
Washington to Mayo Clinic by subway, train, bus, and foot
Questions & Answers
The cheapest way to get from Washington to Mayo Clinic is to drive which costs $180 - $280 and takes 17h 39m.
The fastest way to get from Washington to Mayo Clinic is to fly and bus which takes 5h 28m and costs $220 - $1,100.
No, there is no direct bus from Washington station to Mayo Clinic. However, there are services departing from Washington Union Station and arriving at Rochester via Chicago Bus Station and Milwaukee. The journey, including transfers, takes approximately 26h 38m.
The distance between Washington and Mayo Clinic is 886 miles. The road distance is 1039.5 miles.
The best way to get from Washington to Mayo Clinic without a car is to bus which takes 26h 38m and costs $200 - $350.
It takes approximately 5h 58m to get from Washington to Mayo Clinic, including transfers.
Washington to Mayo Clinic bus services, operated by Greyhound USA, depart from Washington Union Station.
The best way to get from Washington to Mayo Clinic is to fly which takes 5h 58m and costs $150 - $800. Alternatively, you can bus, which costs $200 - $350 and takes 26h 38m.
Washington to Mayo Clinic bus services, operated by Greyhound USA, arrive at Chicago Bus Station.
Yes, the driving distance between Washington to Mayo Clinic is 1039 miles. It takes approximately 17h 39m to drive from Washington to Mayo Clinic.
What companies run services between Washington, DC, USA and Mayo Clinic, MN, USA?
United Airlines, American Airlines, and Delta fly from Ronald Reagan Washington National Airport (DCA) to Rochester (RST) every 4 hours. Alternatively, you can take a bus from Washington Union Station to Mayo Clinic via Chicago Bus Station, Milwaukee Intermodal Station, Milwaukee, and Rochester in around 26h 38m.
- Website
- delta.com
Flights from Ronald Reagan Washington National Airport to Rochester via Minneapolis–Saint Paul International Airport
- Ave. Duration
- 6h 26m
- When
- Every day
- Estimated price
- $160–800
Flights from Ronald Reagan Washington National Airport to Rochester via Detroit, Minneapolis–Saint Paul International Airport
- Ave. Duration
- 7h 25m
- When
- Every day
- Estimated price
- $160–800
Flights from Ronald Reagan Washington National Airport to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 2h 43m
- When
- Every day
- Estimated price
- $190–950
Flights from Ronald Reagan Washington National Airport to Minneapolis–Saint Paul International Airport via Detroit
- Ave. Duration
- 5h 4m
- When
- Every day
- Estimated price
- $190–950
Flights from Ronald Reagan Washington National Airport to Minneapolis–Saint Paul International Airport via Madison
- Ave. Duration
- 5h 18m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $190–950
Flights from Baltimore-Washington International Airport to Rochester via Minneapolis–Saint Paul International Airport
- Ave. Duration
- 5h 43m
- When
- Every day
- Estimated price
- $110–550
Flights from Baltimore-Washington International Airport to Rochester via Detroit, Minneapolis–Saint Paul International Airport
- Ave. Duration
- 7h 5m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $110–550
Flights from Washington Dulles International Airport to Rochester via Minneapolis–Saint Paul International Airport
- Ave. Duration
- 5h 12m
- When
- Every day
- Estimated price
- $95–450
Flights from Washington Dulles International Airport to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 3h 1m
- When
- Every day
- Estimated price
- $110–550
Flights from Washington Dulles International Airport to Minneapolis–Saint Paul International Airport via Detroit
- Ave. Duration
- 5h 13m
- When
- Every day
- Estimated price
- $110–550
Flights from Baltimore-Washington International Airport to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 2h 40m
- When
- Every day
- Estimated price
- $130–650
Flights from Baltimore-Washington International Airport to Minneapolis–Saint Paul International Airport via Detroit
- Ave. Duration
- 4h 58m
- When
- Every day
- Estimated price
- $130–650
- Website
- aa.com
Flights from Ronald Reagan Washington National Airport to Rochester via Chicago O'Hare
- Ave. Duration
- 5h 31m
- When
- Every day
- Estimated price
- $150–750
Flights from Ronald Reagan Washington National Airport to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 2h 55m
- When
- Every day
- Estimated price
- $190–950
Flights from Baltimore-Washington International Airport to Rochester via Chicago O'Hare
- Ave. Duration
- 6h 27m
- When
- Every day
- Estimated price
- $100–500
Flights from Washington Dulles International Airport to Rochester via Chicago O'Hare
- Ave. Duration
- 6h 22m
- When
- Every day
- Estimated price
- $85–420
- Website
- southwest.com
Flights from Ronald Reagan Washington National Airport to Minneapolis–Saint Paul International Airport via Chicago Midway
- Ave. Duration
- 4h 50m
- When
- Monday, Thursday, Friday, and Saturday
- Estimated price
- $190–950
Flights from Baltimore-Washington International Airport to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 2h 35m
- When
- Every day
- Estimated price
- $130–650
- Website
- united.com
Flights from Ronald Reagan Washington National Airport to Rochester via Chicago O'Hare
- Ave. Duration
- 4h 43m
- When
- Every day
- Estimated price
- $150–750
Flights from Baltimore-Washington International Airport to Rochester via Chicago O'Hare
- Ave. Duration
- 5h 8m
- When
- Every day
- Estimated price
- $100–500
Flights from Washington Dulles International Airport to Rochester via Chicago O'Hare
- Ave. Duration
- 4h 58m
- When
- Every day
- Estimated price
- $85–420
Flights from Washington Dulles International Airport to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 2h 43m
- When
- Every day
- Estimated price
- $110–550
- Website
- suncountry.com
Flights from Washington Dulles International Airport to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 2h 37m
- When
- Sunday and Thursday
- Estimated price
- $110–550
Flights from Baltimore-Washington International Airport to Minneapolis–Saint Paul International Airport
- Ave. Duration
- 2h 40m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $130–650
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Washington Union Station to Chicago Union Station
- Ave. Duration
- 17h 48m
- Frequency
- Once daily
- Estimated price
- $250–550
- Website
- https://www.amtrak.com/home.html
Train from Washington Union Station to BWI Thurgood Marshall
- Ave. Duration
- 35 min
- Frequency
- Every 30 minutes
- Estimated price
- $9–20
- Website
- https://www.amtrak.com/home.html
Train from Washington Union Station to BWI Thurgood Marshall
- Ave. Duration
- 35 min
- Frequency
- Every 30 minutes
- Estimated price
- $9–20
- Website
- https://www.amtrak.com/home.html
Train from Rockville Amtrak to Chicago Union Station
- Ave. Duration
- 17h 24m
- Frequency
- Once daily
- Estimated price
- $240–500
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to St. Paul-Minneapolis
- Ave. Duration
- 7h 31m
- Frequency
- 3 times a day
- Estimated price
- $130–270
- Website
- https://www.amtrak.com/home.html
- Phone
- 1-866-743-3682
- Website
- mta.maryland.gov
Train from Washington Union Station to BWI Thurgood Marshall
- Ave. Duration
- 35 min
- Frequency
- Hourly
- Estimated price
- $2–9
- Website
- https://www.mta.maryland.gov
- Standard Fare
- $2–9
Train from Washington Union Station to BWI Thurgood Marshall
- Ave. Duration
- 35 min
- Frequency
- Hourly
- Estimated price
- $2–9
- Website
- https://www.mta.maryland.gov
- Standard Fare
- $2–9
Rome2Rio's guide to Amtrak Acela
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Washington Union Station to BWI Thurgood Marshall
- Ave. Duration
- 20 min
- Frequency
- Every 4 hours
- Estimated price
- $6–550
- Schedules at
- https://www.amtrak.com/acela-train
- Website
- https://www.amtrak.com/home.html
- Business Class
- $6–440
- First Class
- $100–550
Train from Washington Union Station to BWI Thurgood Marshall
- Ave. Duration
- 20 min
- Frequency
- Every 4 hours
- Estimated price
- $6–550
- Schedules at
- https://www.amtrak.com/acela-train
- Website
- https://www.amtrak.com/home.html
- Business Class
- $6–440
- First Class
- $100–550
- Phone
- +1 202 466 3876
- Website
- wmata.com
Subway from Farragut West, Blue/Orange/Silver Line Track 2 Platform to Washington Dulles International Airport, Silver Line Center Platform
- Ave. Duration
- 47 min
- Frequency
- Every 15 minutes
- Estimated price
- $2–3
- Website
- https://www.wmata.com
- standard fare after 9:30 p.m
- $2–3
Subway from Farragut West, Blue/Orange/Silver Line Track 2 Platform to Washington Dulles International Airport, Silver Line Center Platform
- Ave. Duration
- 47 min
- Frequency
- Every 15 minutes
- Estimated price
- $2–3
- Website
- https://www.wmata.com
- standard fare after 9:30 p.m
- $2–3
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Washington Union Station to Chicago Bus Station
- Ave. Duration
- 17h 10m
- Frequency
- Twice daily
- Estimated price
- $110–220
- Website
- https://www.greyhound.com/
Bus from Chicago Bus Station to Milwaukee Intermodal Station
- Ave. Duration
- 1h 40m
- Frequency
- 4 times a day
- Estimated price
- $14–28
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Chicago Bus Station to Milwaukee Intermodal Station
- Ave. Duration
- 1h 55m
- Frequency
- 3 times a day
- Estimated price
- $14–24
- Schedules at
- flixbus.com
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Milwaukee to Rochester
- Ave. Duration
- 5h 40m
- Frequency
- Twice daily
- Estimated price
- $70–100
- Book at
- https://www.jeffersonlines.com
- Adult
- $70–100
Bus from Madison to Rochester
- Ave. Duration
- 4h 20m
- Frequency
- Twice daily
- Estimated price
- $50–75
- Book at
- https://www.jeffersonlines.com
- Adult
- $50–75
Bus from St. Paul to Rochester, MN
- Ave. Duration
- 1h 30m
- Frequency
- Twice daily
- Estimated price
- $28–40
- Book at
- https://www.jeffersonlines.com
- Adult
- $28–40
- Phone
- +1 (866) 912 - 6224
- [email protected]
- Website
- coachusa.com
Bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campus
- Ave. Duration
- 3h 50m
- Frequency
- Hourly
- Estimated price
- $25–55
- Schedules at
- coachusa.com
- Adult
- $25–55
- Phone
- + 1 507-280-9270
- Website
- groometransportation.com
Bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochester
- Ave. Duration
- 1h 30m
- Frequency
- Every 4 hours
- Estimated price
- $40–50
- Website
- https://groometransportation.com/minneapolis-st-paul-airport/rochester
Bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochester
- Ave. Duration
- 1h 30m
- Frequency
- Every 4 hours
- Estimated price
- $40–50
- Website
- https://groometransportation.com/minneapolis-st-paul-airport/rochester
Bus from Minneapolis / St Paul Airport to Groome Transportation Office - Rochester
- Ave. Duration
- 1h 30m
- Frequency
- Every 4 hours
- Estimated price
- $40–50
- Website
- https://groometransportation.com/minneapolis-st-paul-airport/rochester
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
There are 73+ hotels available in Mayo Clinic.

















