Rome2Rio

How to get fromWaterloo to St. Louisby plane, bus, train, car, or bus (Greyhound, Flixbus)

Find Transport to St. Louis

See all options

There are 7 ways to get from Waterloo to St. Louis by plane, bus, train, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Waterloo Municipal Airport

    best
    1. Fly from Waterloo Municipal Airport (ALO) to Lambert–St. Louis International Airport (STL)plane plane ALO - STL
    6h 6m
    $103–507

  2. Drive  336.7 mi

    cheapest
    1. Drive from Waterloo to St. Louiscar car 336.7 mi
    5h 57m
    $62–89

  3. Bus, train via Chicago

    1. Take the bus from Waterloo to Chicago Bus Stationbus bus Greyhound US0154S
    2. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    12h 55m
    $123–268

  4. Drive to The Eastern Iowa Airport, fly

    1. Drive from Waterloo to Cedar-Rapids-Airport-CIDcar car
    2. Fly from The Eastern Iowa Airport (CID) to Lambert–St. Louis International Airport (STL)plane plane CID - STL
    5h 37m
    $89–490

  5. Drive to Mason City, fly

    1. Drive from Waterloo to Mason-City-Airport-MCWcar car
    2. Fly from Mason City (MCW) to Lambert–St. Louis International Airport (STL)plane plane MCW - STL
    6h 20m
    $104–516

  6. Bus

    1. Take the bus from Waterloo to Chicago Bus Stationbus bus Greyhound US0154S
    2. Take the bus from Chicago Bus Station to St Louis Bus Stationbus bus FlixBus 2510 / ...
    13h 55m
    $98–173

  7. Bus, train

    1. Take the bus from Waterloo to Des Moinesbus bus
    2. Take the bus from Des Moines to Galesburgbus bus
    3. Take the bus from Galesburg Amtrak Station to Springfieldbus bus
    4. Take the train from Springfield to St. Louistrain train
    14h 28m
    $104–205

Waterloo to St. Louis by bus, foot, and train

Calendar5Weekly Services
Duration12h 55mAverage Duration
Ticket$123Cheapest Price
See schedules

Questions & Answers

Map of how to get from Waterloo to St. Louis.ExpandLaunch map view
  • Distance: 303.8 mi
  • Duration: 6h 6m

What companies run services between Waterloo, IA, USA and St. Louis, MO, USA?

American Airlines flies from Waterloo Municipal Airport (ALO) to Lambert–St. Louis International Airport (STL) 4 times a day. Alternatively, you can take a bus from Waterloo to St Louis Bus Station via Chicago Bus Station in around 13h 55m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers