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How to get fromWaterville to Louisvilleby bus, plane, train, bus (Greyhound, Amtrak), car, taxi, or bus (Flixbus, Amtrak)

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There are 10 ways to get from Waterville to Louisville by bus, plane, train, bus (Greyhound, Amtrak), car, taxi, or bus (Flixbus, Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Portland, fly

    best
    1. Take the bus from Waterville to City of Portlandbus bus
    2. Fly from Portland (PWM) to Louisville International Airport (SDF)plane plane PWM - SDF
    9h 28m
    $206–990

  2. Bus to Bangor, fly

    cheapest
    1. Take the bus from Waterville to Bangor Park & Ridebus bus
    2. Fly from Bangor (BGR) to Louisville International Airport (SDF)plane plane BGR - SDF
    9h 13m
    $179–886

  3. Bus, train via Toledo

    1. Take the bus from Colby College Museum of Art to Boston, MA - South Stationbus bus
    2. Take the train from Boston to Toledotrain train
    3. Take the bus from Toledo to Indianapolisbus bus
    4. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    30h 12m
    $521–874

  4. Bus

    1. Take the bus from Colby College Museum of Art to Boston, MA - South Stationbus bus
    2. Take the bus from Boston to New Yorkbus bus
    3. Take the bus from Port Authority Bus Terminal to Indianapolis Union Stationbus bus
    4. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    30h 27m
    $250–404

  5. Drive  1,109.6 mi

    1. Drive from Waterville to Louisvillecar car 1,109.6 mi
    19h 50m
    $203–293

  6. Bus to Boston Logan Airport, fly

    1. Take the bus from Colby College Museum of Art to Logan International Airportbus bus
    2. Fly from Boston Logan Airport (BOS) to Louisville International Airport (SDF)plane plane BOS - SDF
    8h 49m
    $209–967

  7. Fly from Augusta State Airport

    1. Fly from Augusta State Airport (AUG) to Louisville International Airport (SDF)plane plane AUG - SDF
    6h 45m
    $234–939

  8. Taxi to Rockland, fly

    1. Take the taxi from Waterville to Rockland (RKD)taxi taxi
    2. Fly from Rockland (RKD) to Louisville International Airport (SDF)plane plane RKD - SDF
    8h 20m
    $304–1,060

  9. Bus via Reading

    1. Take the bus from Colby College Museum of Art to Boston, MA - South Stationbus bus
    2. Take the bus from Boston to New York Midtownbus bus
    3. Take the bus from New York Midtown to Cincinnatibus bus
    4. Take the bus from Cincinnati to Indianapolisbus bus
    5. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    33h 57m
    $234–419

  10. Bus, train

    1. Take the bus from Colby College Museum of Art to Boston, MA - South Stationbus bus
    2. Take the train from Boston to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the train from Ny Moynihan Train Hall At Penn Station to Indianapolistrain train
    4. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    35h 44m
    $620–1,659

Portland (PWM) to Louisville International Airport (SDF) flights

Calendar60Weekly Planes
Duration6h 13mAverage Duration
Ticket$187Cheapest Price
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Comparing Your Travel Options

Map of how to get from Waterville to Louisville.ExpandLaunch map view
  • Distance: 986.8 mi
  • Duration: 9h 28m

What companies run services between Waterville, ME, USA and Louisville, KY, USA?

You can take a vehicle from Waterville to Louisville, KY via Colby College Museum of Art, Boston, MA - South Station, Boston, New York, Port Authority Bus Terminal, and Indianapolis Union Station in around 30h 27m. Alternatively, Cape Air, Delta, and three other airlines fly from Augusta State Airport (AUG) to Louisville International Airport (SDF) 3 times a day.

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