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How to get fromWayne to Charlestonby train, plane, train (Amtrak), bus (Greyhound), or car

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There are 7 ways to get from Wayne to Charleston by train, plane, train (Amtrak), bus (Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Philadelphia International Airport, fly

    best
    1. Take the train from Wayne to Gray 30th St Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Charleston International Airport (CHS)plane plane PHL - CHS
    5h 48m
    $338–908

  2. Drive 633.7 mi

    cheapest
    1. Drive from Wayne to Charlestoncar car 633.7 mi
    12h 3m
    $116–167

  3. Train (Amtrak)

    1. Take the train from 30th Street Station to Charleston Amtrak Stationtrain train Silver Meteor / ...
    14h 23m
    $233–463

  4. Bus (Greyhound)

    1. Take the bus from Philadelphia Bus Station to Raleigh Bus Stationbus bus Greyhound US0670
    2. Take the bus from Raleigh Bus Station to Charleston Bus Stationbus bus Greyhound US0645S
    22h 32m
    $120–230

  5. Train to Baltimore-Washington International Airport, fly

    1. Take the train from 30th Street Station to BWI Thurgood Marshalltrain train
    2. Fly from Baltimore-Washington International Airport (BWI) to Charleston International Airport (CHS)plane plane BWI - CHS
    6h 50m
    $419–1,855

  6. Train to John F. Kennedy International Airport, fly

    1. Take the train from 30th Street Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Fly from John F. Kennedy International Airport (JFK) to Charleston International Airport (CHS)plane plane JFK - CHS
    7h 34m
    $689–1,824

  7. Train to Newark Liberty International Airport, fly

    1. Take the train from 30th Street Station to Newark Liberty International Airporttrain train
    2. Fly from Newark Liberty International Airport (EWR) to Charleston International Airport (CHS)plane plane EWR - CHS
    7h 31m
    $400–1,160

Wayne to Charleston by bus and foot (Greyhound)

Calendar14Weekly Services
Duration22h 32mAverage Duration
Ticket$120Cheapest Price
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Questions & Answers

Map of how to get from Wayne to Charleston.ExpandLaunch map view
  • Distance: 587.3 mi
  • Duration: 5h 48m

What companies run services between Wayne, PA, USA and Charleston, SC, USA?

Amtrak operates a train from 30th Street Station to Charleston Amtrak Station twice daily. Tickets cost $200–420 and the journey takes 12h 33m. Alternatively, you can take a bus from Lancaster Av & Wayne Av to Transit Mall via 69th St Transit Center North Terminal, 69th St Transit Center South Terminal, Chestnut St & 12th St, Philadelphia Bus Station, Raleigh Bus Station, Charleston Bus Station, North Charleston Transit Center, N. Charleston SuperStop, and Rivers Ave / Cosgrove Ave in around 22h 32m.

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