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How to get fromWayne to Indianapolisby train, plane, bus, train (Amtrak), car, or bus (Greyhound)

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There are 9 ways to get from Wayne to Indianapolis by train, plane, bus, train (Amtrak), car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Philadelphia International Airport, fly

    best
    1. Take the train from Wayne to Gray 30th St Stationtrain train
    2. Fly from Philadelphia International Airport (PHL) to Indianapolis (IND)plane plane PHL - IND
    5h 26m
    $158–858

  2. Bus

    cheapest
    1. Take the bus from Norristown to Indianapolis Union Stationbus bus Greyhound US0421
    18h 3m
    $104–199

  3. Train, bus

    1. Take the train from Paoli Amtrak Station to Harrisburgtrain train Keystone Service / ...
    2. Take the bus from Harrisburg Bus Station to Indianapolisbus bus FlixBus N2640
    15h 54m

  4. Train (Amtrak)

    1. Take the train from 30th Street Station to Indianapolistrain train Cardinal
    23h 17m
    $273–603

  5. Drive 625.4 mi

    1. Drive from Wayne to Indianapoliscar car 625.4 mi
    10h 45m
    $115–165

  6. Train to Baltimore-Washington International Airport, fly

    1. Take the train from 30th Street Station to BWI Thurgood Marshalltrain train
    2. Fly from Baltimore-Washington International Airport (BWI) to Indianapolis (IND)plane plane BWI - IND
    6h 27m
    $429–1,755

  7. Train to John F. Kennedy International Airport, fly

    1. Take the train from 30th Street Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Fly from John F. Kennedy International Airport (JFK) to Indianapolis (IND)plane plane JFK - IND
    7h 25m
    $439–2,224

  8. Train to Newark Liberty International Airport, fly

    1. Take the train from 30th Street Station to Newark Liberty International Airporttrain train
    2. Fly from Newark Liberty International Airport (EWR) to Indianapolis (IND)plane plane EWR - IND
    7h 5m
    $250–1,660

  9. Train to Laguardia Airport, fly

    1. Take the train from 30th Street Station to Ny Moynihan Train Hall At Penn Stationtrain train
    2. Fly from Laguardia Airport (LGA) to Indianapolis (IND)plane plane LGA - IND
    7h 57m
    $163–1,322

Philadelphia International Airport (PHL) to Indianapolis (IND) flights

Calendar69Weekly Planes
Duration3h 11mAverage Duration
Ticket$140Cheapest Price
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Questions & Answers

Map of how to get from Wayne to Indianapolis.ExpandLaunch map view
  • Distance: 622.7 mi
  • Duration: 5h 26m

What companies run services between Wayne, PA, USA and Indianapolis, IN, USA?

Amtrak operates a train from 30th Street Station to Indianapolis 3 times a week. Tickets cost $270–600 and the journey takes 21h 40m. Alternatively, Greyhound-us operates a bus from Norristown to Indianapolis Union Station once daily, and the journey takes 15h. Greyhound USA also services this route once daily.

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