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How to get fromWentzville to Knoxvilleby taxi, plane, bus (Greyhound), train, bus, or car

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There are 6 ways to get from Wentzville to Knoxville by taxi, plane, bus (Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi, fly

    best
    1. Take the taxi from Wentzville to St-Louis-Airport-STLtaxi taxi
    2. Fly from Lambert–St. Louis International Airport (STL) to Mcghee Tyson Airport (TYS)plane plane STL - TYS
    4h 48m
    $245–903

  2. Drive 510.3 mi

    cheapest
    1. Drive from Wentzville to Knoxvillecar car 510.3 mi
    9h 8m
    $94–135

  3. Bus via Farragut

    1. Take the bus from St Louis Bus Station to Port Authority Bus Terminalbus bus Greyhound US0421
    2. Take the bus from New York to Knoxvillebus bus Nyc
    41h 8m
    $378–606

  4. Train, bus

    1. Take the train from Washington Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the bus from New York to Knoxvillebus bus Nyc
    42h 17m
    $645–1,196

  5. Bus

    1. Take the bus from St Louis Bus Station to Port Authority Bus Terminalbus bus Greyhound US0421
    2. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    41h 9m
    $333–516

  6. Train, bus via Ossining

    1. Take the train from Washington Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Croton-Harmon Amtrak Stationtrain train
    3. Take the train from Croton-Harmon to 125th Street - Harlemtrain train
    4. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    42h 47m
    $600–1,123

Lambert–St. Louis International Airport (STL) to Mcghee Tyson Airport (TYS) flights

Calendar113Weekly Planes
Duration5h 2mAverage Duration
Ticket$128Cheapest Price
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Questions & Answers

Map of how to get from Wentzville to Knoxville.ExpandLaunch map view
  • Distance: 445.6 mi
  • Duration: 4h 48m

What companies run services between Wentzville, MO, USA and Knoxville, TN, USA?

You can take a vehicle from Wentzville to Knoxville via St Louis Premium Outlets, Clayton Transit Center, CLAYTON station, CIVIC CENTER station, St Louis Bus Station, Port Authority Bus Terminal, 34 St-Herald Sq, East Broadway, New York, and Knoxville in around 41h 8m.

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