There are 9 ways to get from Wesley Chapel to Florida Keys by car, plane, train, bus, shuttle, or bus (Flixbus, Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Drive to Orlando Sanford, fly to Key West International Airport
best- Drive from Wesley Chapel to Orlando-Sanford-Airport-SFBcar
- Fly from Orlando Sanford (SFB) to Key West International Airport (EYW)plane SFB - EYW
6h 24m$130–369Drive 383 mi
cheapest- Drive from Wesley Chapel to Florida Keyscar 383 mi
7h 49m$70–101Train, bus
- Take the train from Tampa to Delray Beach Amtraktrain
- Take the train from Delray Beach Station to Miami Airport Stationtrain
- Take the bus from Miami Airport Station to Big Pine Keybus
12h 44m$158–271Bus, shuttle
- Take the bus from University of South Florida - 3801 USF Holly Dr to Miami Airportbus Tallahassee
- Take a shuttle bus from Miami, FL - International Airport to Summerland Key - Mote Marine LabTo the Keys
14h 27m$222–320Bus to Tampa, fly to Key West International Airport, bus
- Take the bus from SR 54 & Saddlebrook Way to Wiregrass Park and Ridebus
- Fly from Tampa (TPA) to Key West International Airport (EYW)plane TPA - EYW
- Take the bus from Whitehead & Eaton to Sugarloaf Key - Lower - Opposite Sugarloaf Lodgebus
8h 2m$176–528Fly Tampa to Miami International Airport, shuttle
- Fly from Tampa (TPA) to Miami International Airport (MIA)plane TPA - MIA
- Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FL
10h 31m$932–1,328Fly Tampa to Fort Lauderdale–Hollywood International Airport, shuttle
- Fly from Tampa (TPA) to Fort Lauderdale–Hollywood International Airport (FLL)plane TPA - FLL
- Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FL
10h 56m$312–798Bus, shuttle, line 300 bus to Saint Petersburg–Clearwater International Airport, fly to Key West International Airport
- Take the bus from SR 54 & Saddlebrook Way to Wiregrass Park and Ridebus
- Take a shuttle bus from Gate Gas Station Wesley Chapel to Tampa International Airport - Red Terminal
- Take the bus from Tpa Rental Car Facility to Psta 34Th St Complex - Shelter - Dbus
- Fly from Saint Petersburg–Clearwater International Airport (PIE) to Key West International Airport (EYW)plane PIE - EYW
- Take the bus from Whitehead & Eaton to Sugarloaf Key - Lower - Opposite Sugarloaf Lodgebus
9h 57m$148–384Bus
- Take the bus from Tampa Bus Station to Miami Airport Stationbus FlixBus 2421 / ...
- Take the bus from Miami Airport Station to Big Pine Keybus Greyhound US0720s
15h 57m$72–140
Wesley Chapel to Florida Keys by bus, shuttle, and foot
Questions & Answers
The cheapest way to get from Wesley Chapel to Florida Keys is to drive which costs $70 - $110 and takes 7h 49m.
The fastest way to get from Wesley Chapel to Florida Keys is to drive and fly which takes 6h 24m and costs $130 - $370.
No, there is no direct bus from Wesley Chapel to Florida Keys. However, there are services departing from SR 54 & Saddlebrook Way and arriving at Sugarloaf Key - Lower - Sugarloaf Lodge via Wiregrass Park n Ride, Tampa Bus Station, Miami Airport Station and Big Pine Key - CVS / MM30. The journey, including transfers, takes approximately 15h 57m.
The distance between Wesley Chapel and Florida Keys is 413 miles. The road distance is 385.2 miles.
The best way to get from Wesley Chapel to Florida Keys without a car is to train and bus which takes 12h 44m and costs $150 - $280.
It takes approximately 6h 24m to get from Wesley Chapel to Florida Keys, including transfers.
Wesley Chapel to Florida Keys bus services, operated by Flixbus USA, depart from Tampa Bus Station.
Wesley Chapel to Florida Keys bus services, operated by Flixbus USA, arrive at Miami Airport Station.
Yes, the driving distance between Wesley Chapel to Florida Keys is 385 miles. It takes approximately 7h 49m to drive from Wesley Chapel to Florida Keys.
There are 869+ hotels available in Florida Keys.
What companies run services between Wesley Chapel, FL, USA and Florida Keys, FL, USA?
You can take a bus from SR 54 & Saddlebrook Way to Florida Keys via Wiregrass Park n Ride, Marion Transit Center, Tampa Bus Station, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 15h 57m.
- Website
- aa.com
Flights from Tampa to Miami International Airport
- Ave. Duration
- 1h 11m
- When
- Every day
- Estimated price
- $40–290
- Website
- flybreeze.com
Flights from Tampa to Key West International Airport
- Ave. Duration
- 1h 18m
- When
- Thursday, Sunday, Monday, Wednesday, Friday, and Tuesday
- Estimated price
- $70–390
Flights from Tampa to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 1h 8m
- When
- Every day
- Estimated price
- $100–470
- Website
- allegiantair.com
Flights from Orlando Sanford to Key West International Airport
- Ave. Duration
- 1h 18m
- When
- Thursday, Sunday, Monday, and Friday
- Estimated price
- $35–250
Flights from Saint Petersburg–Clearwater International Airport to Key West International Airport
- Ave. Duration
- 1h 4m
- When
- Wednesday, Thursday, Sunday, Monday, Friday, and Saturday
- Estimated price
- $35–240
- Website
- southwest.com
Flights from Tampa to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 1h 6m
- When
- Every day
- Estimated price
- $40–300
- Website
- jetblue.com
Flights from Tampa to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- $40–300
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Tampa to Delray Beach Amtrak
- Ave. Duration
- 4h 10m
- Frequency
- Once daily
- Estimated price
- $65–140
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 800-874-7245
- [email protected]
- Website
- tri-rail.com
Train from Delray Beach Station to Miami Airport Station
- Ave. Duration
- 1h 24m
- Frequency
- Hourly
- Estimated price
- $5–9
- Website
- https://www.tri-rail.com
- Weekend | Holiday
- $5
- Weekday
- $6–9
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a day
- Estimated price
- $20–40
- Website
- https://www.greyhound.com/
Bus from Tampa Bus Station to Miami Airport Station
- Ave. Duration
- 8h
- Frequency
- Once daily
- Estimated price
- $45–90
- Website
- https://www.greyhound.com/
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a day
- Estimated price
- $20–40
- Website
- https://www.greyhound.com/
- Phone
- +1 877 733 0724
- Website
- redcoachusa.com
Bus from University of South Florida - 3801 USF Holly Dr to Miami Airport
- Ave. Duration
- 5h 25m
- Frequency
- Once daily
- Estimated price
- $65–130
- Website
- https://www.redcoachusa.com
- Phone
- +1 (305) 289-9997
- [email protected]
- Website
- keysshuttle.com
Shuttle from Miami, FL - International Airport to Summerland Key - Mote Marine Lab
- Ave. Duration
- 3h 30m
- Frequency
- 3 times a day
- Estimated price
- $150–180
- Website
- https://www.keysshuttle.com
Shuttle from Miami, FL - International Airport to Big Pine Key, FL
- Ave. Duration
- 3h
- Frequency
- 3 times a day
- Estimated price
- $150–180
- Website
- https://www.keysshuttle.com
Shuttle from Fort Lauderdale, FL - International Airport to Big Pine Key, FL
- Ave. Duration
- 3h 30m
- Frequency
- 3 times a day
- Estimated price
- $170–200
- Website
- https://www.keysshuttle.com
- Phone
- +1 727-834-3322
- [email protected]
- Website
- pascocountyfl.net
Bus from SR 54 & Saddlebrook Way to Wiregrass Park and Ride
- Ave. Duration
- 26 min
- Frequency
- Every 2 hours
- Estimated price
- $2
- Website
- https://www.pascocountyfl.net/services/gopasco/index.php
Bus from SR 54 & Saddlebrook Way to Wiregrass Park and Ride
- Ave. Duration
- 26 min
- Frequency
- Every 2 hours
- Estimated price
- $2
- Website
- https://www.pascocountyfl.net/services/gopasco/index.php
- Phone
- +1 305-809-3700
- Website
- cityofkeywest-fl.gov
Bus from Whitehead & Eaton to Sugarloaf Key - Lower - Opposite Sugarloaf Lodge
- Ave. Duration
- 36 min
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- https://www.cityofkeywest-fl.gov/595/Schedules-and-Route-Maps
Bus from Whitehead & Eaton to Sugarloaf Key - Lower - Opposite Sugarloaf Lodge
- Ave. Duration
- 36 min
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- https://www.cityofkeywest-fl.gov/595/Schedules-and-Route-Maps
- Phone
- +1 352 539 9664
- Website
- groometransportation.com
Shuttle from Gate Gas Station Wesley Chapel to Tampa International Airport - Red Terminal
- Ave. Duration
- 41 min
- Frequency
- Hourly
- Estimated price
- $26–40
- Website
- https://groometransportation.com/the-villages/?&sd_client_id=992f7c93-d719-43a2-9d9e-8c8cbbd08d74
- online discount
- $26–35
- call in
- $30–40
- Phone
- +1 727-540-1900
- [email protected]
- Website
- psta.net
Bus from Tpa Rental Car Facility to Psta 34Th St Complex - Shelter - D
- Ave. Duration
- 32 min
- Frequency
- Every 3 hours
- Estimated price
- $3
- Schedules at
- psta.net
- Adult
- $3
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Tampa Bus Station to Miami Airport Station
- Ave. Duration
- 6h
- Frequency
- 5 times a day
- Estimated price
- $45–75
- Schedules at
- flixbus.com
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