Rome2Rio

How to get fromWesley Chapel to Greenvilleby bus, plane, bus (Flixbus), train, car, or taxi

Find Transport to Greenville

See all options

There are 6 ways to get from Wesley Chapel to Greenville by bus, plane, bus (Flixbus), train, car, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Tampa, fly to Greenville–Spartanburg International Airport

    best
    1. Take the bus from SR 54 & Saddlebrook Way to Wiregrass Park and Ridebus bus
    2. Fly from Tampa (TPA) to Greenville–Spartanburg International Airport (GSP)plane plane TPA - GSP
    5h 51m
    $154–418

  2. Drive 510.7 mi

    cheapest
    1. Drive from Wesley Chapel to Greenvillecar car 510.7 mi
    10h 38m
    $94–135

  3. Bus

    1. Take the bus from University of South Florida to Atlanta Bus Stationbus bus FlixBus N2467
    2. Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus bus Charlotte
    16h 35m
    $138–298

  4. Train, bus

    1. Take the train from Tampa to Carytrain train
    2. Take the train from Cary to Charlotte Amtrak Stationtrain train
    3. Take the bus from Charlotte to Taqueria Guadalajara - Greenvillebus bus
    24h 5m
    $392–830

  5. Drive to Orlando Sanford, fly to Asheville Regional Airport, taxi

    1. Drive from Wesley Chapel to Orlando-Sanford-Airport-SFBcar car
    2. Fly from Orlando Sanford (SFB) to Asheville Regional Airport (AVL)plane plane SFB - AVL
    3. Take the taxi from Asheville-Airport-AVL to Greenvilletaxi taxi
    4h 53m
    $213–535

  6. Drive to Orlando Sanford, fly to Greenville–Spartanburg International Airport

    1. Drive from Wesley Chapel to Orlando-Sanford-Airport-SFBcar car
    2. Fly from Orlando Sanford (SFB) to Greenville–Spartanburg International Airport (GSP)plane plane SFB - GSP
    4h 2m
    $133–560

Tampa (TPA) to Greenville–Spartanburg International Airport (GSP) flights

Calendar79Weekly Planes
Duration3h 41mAverage Duration
Ticket$75Cheapest Price
See schedules

Questions & Answers

Map of how to get from Wesley Chapel to Greenville.ExpandLaunch map view
  • Distance: 526.1 mi
  • Duration: 5h 51m

What companies run services between Wesley Chapel, FL, USA and Greenville, SC, USA?

You can take a bus from SR 54 & Saddlebrook Way to Greenville via Wiregrass Park n Ride, University Area Transit Center, UATC to Mall/ Library, University of South Florida, Atlanta Bus Station, Garnett Station, Doraville Station, Atlanta, and Taqueria Guadalajara - Greenville in around 16h 35m.

Airlines
Train operators
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides