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How to get fromWesley Chapel to Panama City Beachby bus (Flixbus, Greyhound), car, plane, bus (Greyhound), or bus

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There are 6 ways to get from Wesley Chapel to Panama City Beach by bus (Flixbus, Greyhound), car, plane, bus (Greyhound), or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus via Gainesville

    best
    1. Take the bus from University of South Florida to Gainesvillebus bus
    2. Take the bus from Gainesville to Tallahasseebus bus
    3. Take the bus from Tallahassee to Panama City Beach Bus Stationbus bus
    9h 20m
    $111–170

  2. Drive 320.8 mi

    cheapest
    1. Drive from Wesley Chapel to Panama City Beachcar car 320.8 mi
    6h 29m
    $59–85

  3. Fly to Northwest Florida Beaches International Airport

    1. Fly from Tampa (TPA) to Northwest Florida Beaches International Airport (ECP)plane plane TPA - ECP
    7h 51m
    $154–498

  4. Bus (Greyhound)

    1. Take the bus from Tampa Bus Station to Tallahasseebus bus Greyhound US0780s
    2. Take the bus from Tallahassee to Panama City Beach Bus Stationbus bus Greyhound US0799 / ...
    12h 21m
    $64–118

  5. Fly to Destin–Fort Walton Beach Airport, drive

    1. Fly from Tampa (TPA) to Destin–Fort Walton Beach Airport (VPS)plane plane TPA - VPS
    2. Drive from Destin–Fort Walton Beach Airport (VPS) to Panama City Beachcar car
    8h 50m
    $114–460

  6. Fly to Pensacola International Airport, bus

    1. Fly from Tampa (TPA) to Pensacola International Airport (PNS)plane plane TPA - PNS
    2. Take the bus from Pensacola Airport to Panama City Beach Bus Stationbus bus
    8h 52m
    $212–544

Tampa (TPA) to Northwest Florida Beaches International Airport (ECP) flights

Calendar86Weekly Planes
Duration5h 28mAverage Duration
Ticket$75Cheapest Price
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Questions & Answers

Map of how to get from Wesley Chapel to Panama City Beach.ExpandLaunch map view
  • Distance: 392.1 mi
  • Duration: 9h 20m

What companies run services between Wesley Chapel, FL, USA and Panama City Beach, FL, USA?

You can take a vehicle from Wesley Chapel to Panama City Beach via University of South Florida, Gainesville, Tallahassee, and Panama City Beach Bus Station in around 9h 20m. Alternatively, Delta, Southwest Airlines, and two other airlines fly from Tampa (TPA) to Northwest Florida Beaches International Airport (ECP) every 2 hours.

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Bus operators

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