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How to get fromWesley Chapel to South Carolinaby bus, plane, train (Amtrak), car, taxi, or train

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There are 7 ways to get from Wesley Chapel to South Carolina by bus, plane, train (Amtrak), car, taxi, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, fly to Greenville–Spartanburg International Airport

    best
    1. Take the bus from SR 54 & Saddlebrook Way to Wiregrass Park and Ridebus bus
    2. Fly from Tampa (TPA) to Greenville–Spartanburg International Airport (GSP)plane plane TPA - GSP
    5h 51m
    $154–418

  2. Drive 405.9 mi

    cheapest
    1. Drive from Wesley Chapel to Charlestoncar car 405.9 mi
    7h 16m
    $75–107

  3. Train (Amtrak)

    1. Take the train from Tampa to Kissimmee Amtrak Stationtrain train Floridian
    2. Take the train from Kissimmee Amtrak Station to Charleston Amtrak Stationtrain train Silver Meteor
    11h 27m
    $249–448

  4. Bus, fly to Charleston International Airport

    1. Take the bus from SR 54 & Saddlebrook Way to Wiregrass Park and Ridebus bus
    2. Fly from Tampa (TPA) to Charleston International Airport (CHS)plane plane TPA - CHS
    6h 27m
    $172–386

  5. Fly to Charlotte Douglas International Airport, taxi

    1. Fly from Tampa (TPA) to Charlotte Douglas International Airport (CLT)plane plane TPA - CLT
    2. Take the taxi from Charlotte-Airport-CLT to Rock Hilltaxi taxi
    6h 16m
    $204–694

  6. Drive, train (Amtrak)

    1. Drive from Wesley Chapel to Kissimmee Amtrak Stationcar car
    2. Take the train from Kissimmee Amtrak Station to Charleston Amtrak Stationtrain train Silver Meteor
    11h 47m
    $147–303

  7. Train, taxi, drive

    1. Take the train from Tampa to Savannah Stationtrain train
    2. Take the taxi from Savannah Station to Trolley Stop 10 - Coligny Beach Parktaxi taxi
    3. Drive from Trolley Stop 1 - Shelter Cove Towne Centre to Charlestoncar car
    16h 6m
    $304–494

Tampa (TPA) to Greenville–Spartanburg International Airport (GSP) flights

Calendar79Weekly Planes
Duration3h 41mAverage Duration
Ticket$75Cheapest Price
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Questions & Answers

Map of how to get from Wesley Chapel to South Carolina.ExpandLaunch map view
  • Distance: 526.1 mi
  • Duration: 5h 51m

What companies run services between Wesley Chapel, FL, USA and South Carolina, USA?

You can take a vehicle from Wesley Chapel to Charleston via Tampa, Kissimmee Amtrak Station, and Charleston Amtrak Station in around 11h 27m.

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