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How to get fromWest Chester to St. Louisby taxi, bus, car, or plane

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There are 7 ways to get from West Chester to St. Louis by taxi, bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Taxi, bus (Greyhound)

    best
    1. Take the taxi from West Chester to Cambridge, OHtaxi taxi
    2. Take the bus from Cambridge, OH to St Louis Bus Stationbus bus Greyhound US0421
    11h 20m
    $154–243

  2. Drive 519.6 mi

    cheapest
    1. Drive from West Chester to St. Louiscar car 519.6 mi
    9h 2m
    $95–137

  3. Bus to Cleveland-Hopkins International Airport, fly

    1. Take the bus from Newcomerstown Bus Stop to Cleveland Ohio Greyhound Stationbus bus
    2. Fly from Cleveland-Hopkins International Airport (CLE) to Lambert–St. Louis International Airport (STL)plane plane CLE - STL
    6h 57m
    $563–1,019

  4. Taxi, bus to John Glenn Columbus International Airport, fly

    1. Take the taxi from West Chester to Cambridge, OHtaxi taxi
    2. Take the bus from Cambridge, OH to Columbusbus bus
    3. Fly from John Glenn Columbus International Airport (CMH) to Lambert–St. Louis International Airport (STL)plane plane CMH - STL
    6h 33m
    $894–1,054

  5. Taxi, bus to Pittsburgh International Airport, fly

    1. Take the taxi from West Chester to Cambridge, OHtaxi taxi
    2. Take the bus from Cambridge, OH to Pittsburgh Intermodal Stationbus bus
    3. Fly from Pittsburgh International Airport (PIT) to Lambert–St. Louis International Airport (STL)plane plane PIT - STL
    7h 49m
    $197–726

  6. Bus to Akron, fly

    1. Take the bus from Newcomerstown Bus Stop to Canton Ohio Sarta Transit Stationbus bus
    2. Fly from Akron (CAK) to Lambert–St. Louis International Airport (STL)plane plane CAK - STL
    8h 48m
    $162–703

  7. Drive to North Central West Virginia Airport, fly

    1. Drive from West Chester to North Central West Virginia Airport (CKB)car car
    2. Fly from North Central West Virginia Airport (CKB) to Lambert–St. Louis International Airport (STL)plane plane CKB - STL
    8h 43m
    $125–635

Cleveland-Hopkins International Airport (CLE) to Lambert–St. Louis International Airport (STL) flights

Calendar63Weekly Planes
Duration3h 17mAverage Duration
Ticket$107Cheapest Price
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Questions & Answers

Map of how to get from West Chester to St. Louis.ExpandLaunch map view
  • Distance: 525.2 mi
  • Duration: 11h 20m

What companies run services between West Chester, OH, USA and St. Louis, MO, USA?

There is no direct connection from West Chester to St. Louis. However, you can take the taxi to Cambridge, OH then take the bus to St Louis Bus Station. Alternatively, you can drive from West Chester to St. Louis in around 9h 2m.

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