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How to get fromWest Chester to Durhamby bus, plane, train (Amtrak), car, train, or bus (Greyhound)

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There are 9 ways to get from West Chester to Durham by bus, plane, train (Amtrak), car, train, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Line 104 bus to Philadelphia International Airport, fly to Raleigh-Durham International Airport

    best
    1. Take the bus from Chestnut St & Darlington St to 69th St Transit Centerbus bus
    2. Fly from Philadelphia International Airport (PHL) to Raleigh-Durham International Airport (RDU)plane plane PHL - RDU
    5h 53m
    $85–395

  2. Bus via Washington

    cheapest
    1. Take the bus from Philadelphia to Union Stationbus bus New York
    2. Take the bus from Washington, DC - 2305 Pennsylvania Ave to Durham, NC - 3446 Hillsborough Rdbus bus New York
    13h 31m
    $64–145

  3. Train (Amtrak)

    1. Take the train from 30th Street Station to Washington Union Stationtrain train Northeast Regional / ...
    2. Take the train from Washington Union Station to Durham Amtrak Stationtrain train Carolinian
    11h 21m
    $146–876

  4. Drive 377.6 mi

    1. Drive from West Chester to Durhamcar car 377.6 mi
    6h 51m
    $69–100

  5. Line 104 bus to Philadelphia International Airport, fly to Piedmont Triad International Airport, train

    1. Take the bus from Chestnut St & Darlington St to 69th St Transit Centerbus bus
    2. Fly from Philadelphia International Airport (PHL) to Piedmont Triad International Airport (GSO)plane plane PHL - GSO
    3. Take the train from Greensboro to Durham Amtrak Stationtrain train
    6h 53m
    $176–834

  6. Line 104 bus, train to Baltimore-Washington International Airport, fly to Raleigh-Durham International Airport

    1. Take the bus from Chestnut St & Darlington St to 69th St Transit Centerbus bus
    2. Take the train from 30th Street Station to BWI Thurgood Marshalltrain train
    3. Fly from Baltimore-Washington International Airport (BWI) to Raleigh-Durham International Airport (RDU)plane plane BWI - RDU
    6h 53m
    $236–1,052

  7. Line 104 bus, train to Ronald Reagan Washington National Airport, fly to Raleigh-Durham International Airport, line 700 bus

    1. Take the bus from Chestnut St & Darlington St to 69th St Transit Centerbus bus
    2. Take the train from 30th Street Station to Washington Union Stationtrain train
    3. Fly from Ronald Reagan Washington National Airport (DCA) to Raleigh-Durham International Airport (RDU)plane plane DCA - RDU
    4. Take the bus from Regional Transit Center to Duke St at Jackson Stbus bus
    7h 37m
    $596–2,069

  8. Line 104 bus, train to Newark Liberty International Airport, fly to Raleigh-Durham International Airport, line 700 bus

    1. Take the bus from Chestnut St & Darlington St to 69th St Transit Centerbus bus
    2. Take the train from 30th Street Station to Newark Liberty International Airporttrain train
    3. Fly from Newark Liberty International Airport (EWR) to Raleigh-Durham International Airport (RDU)plane plane EWR - RDU
    4. Take the bus from Regional Transit Center to Duke St at Jackson Stbus bus
    7h 33m
    $278–1,267

  9. Bus (Greyhound)

    1. Take the bus from Philadelphia Bus Station to Durhambus bus Greyhound US0670
    13h 51m
    $71–136

West Chester to Durham by bus, subway, and train (Amtrak)

Calendar7Weekly Services
Duration11h 21mAverage Duration
Ticket$146Cheapest Price
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Questions & Answers

Map of how to get from West Chester to Durham.ExpandLaunch map view
  • Distance: 387.4 mi
  • Duration: 5h 53m

What companies run services between West Chester, PA, USA and Durham, NC, USA?

You can take a bus from Chestnut St & Darlington St to Durham Amtrak Station via 69th St Transit Center, 69th St Transit Center, Drexel Station at 30th St, 30th Street Station, and Washington Union Station in around 11h 21m. Alternatively, you can take a bus from Chestnut St & Darlington St to Durham Station via 69th St Transit Center, 69th St Transit Center, Drexel Station at 30th St, Philadelphia, Union Station, Massachusetts Av NE+1 St NE, Pennsylvania Av SE+L'Enfant Sq SE, Washington, DC - 2305 Pennsylvania Ave, Durham, NC - 3446 Hillsborough Rd, and Hillsborough Rd at LaSalle St in around 13h 31m.

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