There are 9 ways to get from West Chester to Greenville by bus, plane, train, bus (Greyhound, Flixbus), car, or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Line 104 bus to Philadelphia International Airport, fly to Greenville–Spartanburg International Airport
best- Take the bus from Chestnut St & Darlington St to 69th St Transit Centerbus
- Fly from Philadelphia International Airport (PHL) to Greenville–Spartanburg International Airport (GSP)plane PHL - GSP
5h 11m$174–804Drive 596.8 mi
cheapest- Drive from West Chester to Greenvillecar 596.8 mi
11h 8m$109–158Train, bus
- Take the train from 30th Street Station to Charlotte Amtrak Stationtrain Crescent / ...
- Take the bus from Charlotte to Taqueria Guadalajara - Greenvillebus Charlotte
17h 12m$222–508Bus
- Take the bus from Philadelphia Bus Station to Charlotte Bus Stationbus Greyhound US0670
- Take the bus from Charlotte to Taqueria Guadalajara - Greenvillebus Charlotte
21h 40m$148–341Line 104 bus to Philadelphia International Airport, fly to Asheville Regional Airport, taxi
- Take the bus from Chestnut St & Darlington St to 69th St Transit Centerbus
- Fly from Philadelphia International Airport (PHL) to Asheville Regional Airport (AVL)plane PHL - AVL
- Take the taxi from Asheville-Airport-AVL to Greenvilletaxi
5h 59m$234–669Line 104 bus, train to Baltimore-Washington International Airport, fly to Greenville–Spartanburg International Airport
- Take the bus from Chestnut St & Darlington St to 69th St Transit Centerbus
- Take the train from 30th Street Station to BWI Thurgood Marshalltrain
- Fly from Baltimore-Washington International Airport (BWI) to Greenville–Spartanburg International Airport (GSP)plane BWI - GSP
6h 3m$160–1,301Fly Philadelphia International Airport to Columbia, drive
- Fly from Philadelphia International Airport (PHL) to Columbia (CAE)plane PHL - CAE
- Drive from Columbia-Airport-CAE to Greenvillecar
6h 48m$247–1,337Train to Ronald Reagan Washington National Airport, fly to Greenville–Spartanburg International Airport
- Take the train from 30th Street Station to Washington Union Stationtrain
- Fly from Ronald Reagan Washington National Airport (DCA) to Greenville–Spartanburg International Airport (GSP)plane DCA - GSP
6h 55m$205–1,558Line 104 bus, train to Newark Liberty International Airport, fly to Greenville–Spartanburg International Airport
- Take the bus from Chestnut St & Darlington St to 69th St Transit Centerbus
- Take the train from 30th Street Station to Newark Liberty International Airporttrain
- Fly from Newark Liberty International Airport (EWR) to Greenville–Spartanburg International Airport (GSP)plane EWR - GSP
6h 50m$486–1,206
Philadelphia International Airport (PHL) to Greenville–Spartanburg International Airport (GSP) flights
Questions & Answers
The cheapest way to get from West Chester to Greenville is to drive which costs $100 - $160 and takes 11h 8m.
The fastest way to get from West Chester to Greenville is to line 104 bus and fly which takes 5h 11m and costs $170 - $850.
No, there is no direct bus from West Chester to Greenville. However, there are services departing from Chestnut St & Darlington St and arriving at Taqueria Guadalajara - Greenville via 69th St Transit Center South Terminal, Philadelphia Bus Station, Trade St & Graham St, Transit Center- Bay O and Charlotte. The journey, including transfers, takes approximately 21h 40m.
The distance between West Chester and Greenville is 564 miles. The road distance is 600.3 miles.
The best way to get from West Chester to Greenville without a car is to train and bus which takes 17h 12m and costs $220 - $550.
It takes approximately 5h 11m to get from West Chester to Greenville, including transfers.
West Chester to Greenville bus services, operated by Greyhound USA, depart from Philadelphia Bus Station.
West Chester to Greenville bus services, operated by Greyhound USA, arrive at Charlotte Bus Station.
Yes, the driving distance between West Chester to Greenville is 600 miles. It takes approximately 11h 8m to drive from West Chester to Greenville.
There are 226+ hotels available in Greenville.
What companies run services between West Chester, PA, USA and Greenville, SC, USA?
You can take a bus from Chestnut St & Darlington St to Greenville via 69th St Transit Center, 69th St Transit Center South Terminal, Chestnut St & 12th St, Philadelphia Bus Station, Charlotte Bus Station, Trade St & Graham St, Transit Center- Bay A, Transit Center- Bay O, Tryon St & Dorton St, Charlotte, and Taqueria Guadalajara - Greenville in around 21h 40m.
- Website
- aa.com
Flights from Philadelphia International Airport to Greenville–Spartanburg International Airport
- Ave. Duration
- 2h
- When
- Every day
- Estimated price
- $130–750
Flights from Philadelphia International Airport to Greenville–Spartanburg International Airport via Charlotte
- Ave. Duration
- 3h 59m
- When
- Every day
- Estimated price
- $130–750
Flights from Philadelphia International Airport to Asheville Regional Airport
- Ave. Duration
- 2h 5m
- When
- Every day
- Estimated price
- $85–490
Flights from Philadelphia International Airport to Asheville Regional Airport via Charlotte
- Ave. Duration
- 4h 10m
- When
- Every day
- Estimated price
- $90–500
Flights from Philadelphia International Airport to Asheville Regional Airport via Ronald Reagan Washington National Airport
- Ave. Duration
- 3h 54m
- When
- Monday to Friday
- Estimated price
- $85–490
Flights from Baltimore-Washington International Airport to Greenville–Spartanburg International Airport via Charlotte
- Ave. Duration
- 3h 41m
- When
- Every day
- Estimated price
- $95–600
Flights from Philadelphia International Airport to Columbia
- Ave. Duration
- 2h 3m
- When
- Every day
- Estimated price
- $220–1,300
Flights from Philadelphia International Airport to Columbia via Charlotte
- Ave. Duration
- 4h 42m
- When
- Every day
- Estimated price
- $230–1,300
Flights from Ronald Reagan Washington National Airport to Greenville–Spartanburg International Airport
- Ave. Duration
- 1h 41m
- When
- Every day
- Estimated price
- $130–850
Flights from Ronald Reagan Washington National Airport to Greenville–Spartanburg International Airport via Charlotte
- Ave. Duration
- 3h 50m
- When
- Every day
- Estimated price
- $130–850
Flights from Newark Liberty International Airport to Greenville–Spartanburg International Airport via Charlotte
- Ave. Duration
- 4h 41m
- When
- Every day
- Estimated price
- $100–550
- Website
- delta.com
Flights from Philadelphia International Airport to Greenville–Spartanburg International Airport via Atlanta
- Ave. Duration
- 4h 28m
- When
- Every day
- Estimated price
- $170–900
Flights from Philadelphia International Airport to Asheville Regional Airport via Atlanta
- Ave. Duration
- 4h 40m
- When
- Every day
- Estimated price
- $110–600
Flights from Baltimore-Washington International Airport to Greenville–Spartanburg International Airport via Atlanta
- Ave. Duration
- 3h 41m
- When
- Every day
- Estimated price
- $130–700
Flights from Philadelphia International Airport to Columbia via Atlanta
- Ave. Duration
- 4h 38m
- When
- Every day
- Estimated price
- $300–1,500
Flights from Ronald Reagan Washington National Airport to Greenville–Spartanburg International Airport via Atlanta
- Ave. Duration
- 3h 51m
- When
- Every day
- Estimated price
- $180–1,000
Flights from Newark Liberty International Airport to Greenville–Spartanburg International Airport via Atlanta
- Ave. Duration
- 4h 25m
- When
- Every day
- Estimated price
- $130–650
- Website
- united.com
Flights from Philadelphia International Airport to Greenville–Spartanburg International Airport via Washington Dulles
- Ave. Duration
- 3h 54m
- When
- Every day
- Estimated price
- $130–750
Flights from Philadelphia International Airport to Columbia via Washington Dulles
- Ave. Duration
- 3h 56m
- When
- Every day
- Estimated price
- $230–1,300
Flights from Newark Liberty International Airport to Greenville–Spartanburg International Airport
- Ave. Duration
- 2h 12m
- When
- Every day
- Estimated price
- $100–550
Flights from Newark Liberty International Airport to Greenville–Spartanburg International Airport via Washington Dulles
- Ave. Duration
- 3h 57m
- When
- Every day
- Estimated price
- $100–550
- Website
- southwest.com
Flights from Baltimore-Washington International Airport to Greenville–Spartanburg International Airport
- Ave. Duration
- 1h 32m
- When
- Every day
- Estimated price
- $95–600
Flights from Ronald Reagan Washington National Airport to Greenville–Spartanburg International Airport via Nashville
- Ave. Duration
- 3h 50m
- When
- Tuesday and Wednesday
- Estimated price
- $210–1,100
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from 30th Street Station to Charlotte Amtrak Station
- Ave. Duration
- 10h 52m
- Frequency
- Twice daily
- Estimated price
- $160–340
- Website
- Amtrak
Train from 30th Street Station to BWI Thurgood Marshall
- Ave. Duration
- 1h 25m
- Frequency
- Hourly
- Estimated price
- $30–70
- Website
- Amtrak
Train from 30th Street Station to Washington Union Station
- Ave. Duration
- 1h 58m
- Frequency
- Hourly
- Estimated price
- $40–90
- Website
- Amtrak
Train from 30th Street Station to Newark Liberty International Airport
- Ave. Duration
- 56 min
- Frequency
- Every 3 hours
- Estimated price
- $25–55
- Website
- Amtrak
Rome2Rio's guide to Amtrak Acela
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from 30th Street Station to BWI Thurgood Marshall
- Ave. Duration
- 1h 22m
- Frequency
- 5 times a day
- Estimated price
- $24–650
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $24–460
- First Class
- $140–650
Train from 30th Street Station to Washington Union Station
- Ave. Duration
- 1h 49m
- Frequency
- Hourly
- Estimated price
- $30–650
- Schedules at
- Amtrak Acela
- Website
- Amtrak
- Business Class
- $30–470
- First Class
- $150–650
- Phone
- +1 215-580-7800
- Website
- SEPTA
Bus from Chestnut St & Darlington St to 69th St Transit Center
- Ave. Duration
- 58 min
- Frequency
- Hourly
- Estimated price
- $3
- Website
- SEPTA
- Schedules at
- SEPTA: World Cup 2026
Bus from Chestnut St & Darlington St to 69th St Transit Center
- Ave. Duration
- 58 min
- Frequency
- Hourly
- Estimated price
- $3
- Website
- SEPTA
- Schedules at
- SEPTA: World Cup 2026
Bus from Chestnut St & Darlington St to 69th St Transit Center
- Ave. Duration
- 58 min
- Frequency
- Hourly
- Estimated price
- $3
- Website
- SEPTA
- Schedules at
- SEPTA: World Cup 2026
Bus from Chestnut St & Darlington St to 69th St Transit Center
- Ave. Duration
- 58 min
- Frequency
- Hourly
- Estimated price
- $3
- Website
- SEPTA
- Schedules at
- SEPTA: World Cup 2026
- Phone
- +1 888 358 6762
- [email protected]
- Website
- Tornado Bus Company
Bus from Charlotte to Taqueria Guadalajara - Greenville
- Ave. Duration
- 2h 27m
- Frequency
- Once daily
- Estimated price
- $40–140
- Schedules at
- Tornado Bus Company
- Adults 11-59
- $40–140
Bus from Charlotte to Taqueria Guadalajara - Greenville
- Ave. Duration
- 2h 27m
- Frequency
- Once daily
- Estimated price
- $40–140
- Schedules at
- Tornado Bus Company
- Adults 11-59
- $40–140
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Philadelphia Bus Station to Charlotte Bus Station
- Ave. Duration
- 14h 30m
- Frequency
- Twice daily
- Estimated price
- $85–170
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Philadelphia Bus Station to Charlotte Bus Station
- Ave. Duration
- 14h 15m
- Frequency
- Once daily
- Estimated price
- $90–160
- Schedules at
- Flixbus USA
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