Rome2Rio

How to get fromWest Chester to Louisvilleby plane, car, bus (Greyhound, Amtrak), train, or bus

Find Transport to Louisville

See all options

There are 8 ways to get from West Chester to Louisville by plane, car, bus (Greyhound, Amtrak), train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Philadelphia International Airport to Blue Grass Airport, drive

    best
    1. Fly from Philadelphia International Airport (PHL) to Blue Grass Airport (LEX)plane plane PHL - LEX
    2. Drive from Lexington-Airport-LEX to Louisvillecar car
    6h 14m
    $109–580

  2. Bus

    1. Take the bus from Philadelphia Bus Station to Indianapolis Union Stationbus bus Greyhound US0421
    2. Take the bus from Indianapolis Union Station to Louisville, KYbus bus Chicago
    20h 31m
    $147–243

  3. Train, bus (Amtrak)

    1. Take the train from 30th Street Station to Indianapolistrain train Cardinal
    2. Take the bus from Indianapolis Union Station to Louisville, KYbus bus Chicago
    26h 50m
    $497–803

  4. Drive  644 mi

    1. Drive from West Chester to Louisvillecar car 644 mi
    11h 2m
    $111–159

  5. Line 104 bus to Philadelphia International Airport, fly to Louisville International Airport

    1. Take the bus from Chestnut St & Darlington St to 69th St Transit Centerbus bus
    2. Fly from Philadelphia International Airport (PHL) to Louisville International Airport (SDF)plane plane PHL - SDF
    6h 30m
    $188–1,115

  6. Train to Baltimore-Washington International Airport, fly to Louisville International Airport

    1. Take the train from 30th Street Station to BWI Thurgood Marshalltrain train
    2. Fly from Baltimore-Washington International Airport (BWI) to Louisville International Airport (SDF)plane plane BWI - SDF
    7h 16m
    $160–1,461

  7. Train to Ronald Reagan Washington National Airport, fly to Louisville International Airport

    1. Take the train from 30th Street Station to Washington Union Stationtrain train
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Louisville International Airport (SDF)plane plane DCA - SDF
    8h 10m
    $210–1,768

  8. Train to Newark Liberty International Airport, fly to Louisville International Airport

    1. Take the train from 30th Street Station to Newark Liberty International Airporttrain train
    2. Fly from Newark Liberty International Airport (EWR) to Louisville International Airport (SDF)plane plane EWR - SDF
    8h
    $186–881

West Chester to Louisville by bus and foot

Calendar14Weekly Services
Duration20h 31mAverage Duration
Ticket$147Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from West Chester to Louisville.ExpandLaunch map view
  • Distance: 623.1 mi
  • Duration: 6h 14m

What companies run services between West Chester, PA, USA and Louisville, KY, USA?

You can take a bus from Chestnut St & Darlington St to Louisville, KY via 69th St Transit Center, 69th St Transit Center South Terminal, Chestnut St & 12th St, Philadelphia Bus Station, and Indianapolis Union Station in around 20h 31m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound