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How to get fromWest Chester to Louisvilleby bus, plane, bus (Greyhound, Amtrak), train, car, or bus (Flixbus, Amtrak)

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There are 9 ways to get from West Chester to Louisville by bus, plane, bus (Greyhound, Amtrak), train, car, or bus (Flixbus, Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Line 104 bus to Philadelphia International Airport, fly to Louisville International Airport

    best
    1. Take the bus from Chestnut St & Darlington St to 69th St Transit Centerbus bus
    2. Fly from Philadelphia International Airport (PHL) to Louisville International Airport (SDF)plane plane PHL - SDF
    6h 15m
    $158–915

  2. Line 104 bus to Philadelphia International Airport, fly to Blue Grass Airport, drive

    cheapest
    1. Take the bus from Chestnut St & Darlington St to 69th St Transit Centerbus bus
    2. Fly from Philadelphia International Airport (PHL) to Blue Grass Airport (LEX)plane plane PHL - LEX
    3. Drive from Lexington-Airport-LEX to Louisvillecar car
    6h 10m
    $100–511

  3. Bus

    1. Take the bus from King of Prussia Park & Ride to Indianapolis Union Stationbus bus Greyhound US0421
    2. Take the bus from Indianapolis Union Station to Louisville, KYbus bus Chicago
    20h 29m
    $137–223

  4. Train, bus (Amtrak)

    1. Take the train from 30th Street Station to Indianapolistrain train Cardinal
    2. Take the bus from Indianapolis Union Station to Louisville, KYbus bus Chicago
    26h 50m
    $497–803

  5. Drive  644 mi

    1. Drive from West Chester to Louisvillecar car 644 mi
    11h 2m
    $118–170

  6. Line 104 bus, train to Baltimore-Washington International Airport, fly to Louisville International Airport

    1. Take the bus from Chestnut St & Darlington St to 69th St Transit Centerbus bus
    2. Take the train from 30th Street Station to BWI Thurgood Marshalltrain train
    3. Fly from Baltimore-Washington International Airport (BWI) to Louisville International Airport (SDF)plane plane BWI - SDF
    7h 11m
    $160–1,411

  7. Train to Ronald Reagan Washington National Airport, fly to Louisville International Airport

    1. Take the train from 30th Street Station to Washington Union Stationtrain train
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Louisville International Airport (SDF)plane plane DCA - SDF
    8h 5m
    $200–1,668

  8. Train to Newark Liberty International Airport, fly to Louisville International Airport

    1. Take the train from 30th Street Station to Newark Liberty International Airporttrain train
    2. Fly from Newark Liberty International Airport (EWR) to Louisville International Airport (SDF)plane plane EWR - SDF
    7h 54m
    $176–831

  9. Bus via Reading

    1. Take the bus from Philadelphia Bus Station to Cincinnatibus bus
    2. Take the bus from Cincinnati to Indianapolisbus bus
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    23h 48m
    $136–283

West Chester to Louisville by bus

Calendar7Weekly Buses
Duration20h 29mAverage Duration
Ticket$137Cheapest Price
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Comparing Your Travel Options

Map of how to get from West Chester to Louisville.ExpandLaunch map view
  • Distance: 614.6 mi
  • Duration: 6h 15m

What companies run services between West Chester, PA, USA and Louisville, KY, USA?

You can take a bus from High St & Washington St - FS to Louisville, KY via Plaza at King of Prussia, South Gulph Rd & Bill Smith Blvd - FS, King of Prussia Park & Ride, and Indianapolis Union Station in around 20h 29m.

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