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How to get fromWest Chester to Winston-Salemby bus, plane, train, bus (Greyhound), car, or bus (Flixbus)

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There are 9 ways to get from West Chester to Winston-Salem by bus, plane, train, bus (Greyhound), car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Line 104 bus to Philadelphia International Airport, fly to Piedmont Triad International Airport

    best
    1. Take the bus from Chestnut St & Darlington St to 69th St Transit Centerbus bus
    2. Fly from Philadelphia International Airport (PHL) to Piedmont Triad International Airport (GSO)plane plane PHL - GSO
    5h 42m
    $148–782

  2. Drive 427.9 mi

    cheapest
    1. Drive from West Chester to Winston-Salemcar car 427.9 mi
    8h 25m
    $79–113

  3. Train, bus

    1. Take the train from 30th Street Station to Greensborotrain train Crescent / ...
    2. Take the bus from Greensboro Bus Stop to Winston Salem(Trans Center)bus bus Greyhound US0670 / ...
    12h 32m
    $140–294

  4. Bus (Greyhound)

    1. Take the bus from Philadelphia Bus Station to Winston Salem(Trans Center)bus bus Greyhound US0670
    15h 46m
    $81–156

  5. Fly Philadelphia International Airport to Charlotte Douglas International Airport, bus

    1. Fly from Philadelphia International Airport (PHL) to Charlotte Douglas International Airport (CLT)plane plane PHL - CLT
    2. Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus bus
    7h 54m
    $130–255

  6. Train to Ronald Reagan Washington National Airport, fly to Piedmont Triad International Airport

    1. Take the train from 30th Street Station to Washington Union Stationtrain train
    2. Fly from Ronald Reagan Washington National Airport (DCA) to Piedmont Triad International Airport (GSO)plane plane DCA - GSO
    7h 27m
    $179–1,536

  7. Line 104 bus, train to Newark Liberty International Airport, fly to Piedmont Triad International Airport

    1. Take the bus from Chestnut St & Darlington St to 69th St Transit Centerbus bus
    2. Take the train from 30th Street Station to Newark Liberty International Airporttrain train
    3. Fly from Newark Liberty International Airport (EWR) to Piedmont Triad International Airport (GSO)plane plane EWR - GSO
    7h 20m
    $145–634

  8. Line 104 bus to Philadelphia International Airport, fly to Raleigh-Durham International Airport, line 700 bus, bus

    1. Take the bus from Chestnut St & Darlington St to 69th St Transit Centerbus bus
    2. Fly from Philadelphia International Airport (PHL) to Raleigh-Durham International Airport (RDU)plane plane PHL - RDU
    3. Take the bus from Regional Transit Center to Durham Stationbus bus
    4. Take the bus from Durham to Winston Salem(Trans Center)bus bus
    8h 29m
    $97–419

  9. Bus via Fredericksburg (Flixbus)

    1. Take the bus from Philadelphia Bus Station to Fredericksburgbus bus FlixBus N2605 / ...
    2. Take the bus from Fredericksburg to Greensboro Bus Stopbus bus FlixBus 2605
    17h 24m
    $97–162

West Chester to Winston-Salem by bus, subway, and train

Calendar14Weekly Services
Duration12h 32mAverage Duration
Ticket$140Cheapest Price
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Questions & Answers

Map of how to get from West Chester to Winston-Salem.ExpandLaunch map view
  • Distance: 421.4 mi
  • Duration: 5h 42m

What companies run services between West Chester, PA, USA and Winston-Salem, NC, USA?

Greyhound USA operates a bus from Philadelphia Bus Station to Winston Salem(Trans Center) once daily. Tickets cost $75–150 and the journey takes 12h 55m.

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