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How to get fromWest Chicago to St. Louisby train (Amtrak), train, bus, car, or plane

Find Transport to St. Louis

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There are 5 ways to get from West Chicago to St. Louis by train (Amtrak), train, bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from West Chicago to Chicago OTCtrain train Up-W
    2. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    6h 58m
    $98–199

  2. Drive 279.2 mi

    cheapest
    1. Drive from West Chicago to St. Louiscar car 279.2 mi
    4h 49m
    $51–74

  3. Train, bus

    1. Take the train from West Chicago to Chicago OTCtrain train Up-W
    2. Take the bus from Chicago Bus Station to St Louis Bus Stationbus bus FlixBus 2510 / ...
    8h 13m
    $58–94

  4. Train to Chicago O'Hare International Airport, fly

    1. Take the train from West Chicago to Chicago OTCtrain train
    2. Fly from Chicago O'Hare International Airport (ORD) to Lambert–St. Louis International Airport (STL)plane plane ORD - STL
    5h 6m
    $280–714

  5. Train to Chicago Midway International Airport, fly

    1. Take the train from West Chicago to Chicago OTCtrain train
    2. Fly from Chicago Midway International Airport (MDW) to Lambert–St. Louis International Airport (STL)plane plane MDW - STL
    4h 59m
    $90–564

West Chicago to St. Louis by train and bus

Calendar38Weekly Services
Duration6h 58mAverage Duration
Ticket$98Cheapest Price
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Questions & Answers

Map of how to get from West Chicago to St. Louis.ExpandLaunch map view
  • Distance: 311.1 mi
  • Duration: 6h 58m

What companies run services between West Chicago, IL, USA and St. Louis, MO, USA?

You can take a train from West Chicago to St. Louis via Chicago OTC, Madison & Canal, Clinton & Jackson, and Chicago Union Station in around 6h 58m.

Airlines
Train operators
Bus operators

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