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How to get fromWest Des Moines to Chicagoby plane, bus (Greyhound), car, bus, or train

Find Transport to Chicago

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There are 5 ways to get from West Des Moines to Chicago by plane, bus (Greyhound), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Chicago O'Hare International Airport

    best
    1. Fly from Des Moines (DSM) to Chicago O'Hare International Airport (ORD)plane plane DSM - ORD
    2h 33m
    $56–278
  2. Bus (Greyhound)

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus Greyhound US0123S / ...
    7h 20m
    $77–117
  3. Drive  336.9 mi

    1. Drive from West Des Moines to Chicagocar car 336.9 mi
    5h 41m
    $62–89
  4. Fly to Chicago Midway International Airport

    1. Fly from Des Moines (DSM) to Chicago Midway International Airport (MDW)plane plane DSM - MDW
    2h 13m
    $66–348
  5. Bus, train

    1. Take the bus from Des Moines to Galesburgbus bus Greyhound US0157S
    2. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain train Carl Sandburg / ...
    8h 40m
    $147–222

Des Moines (DSM) to Chicago O'Hare International Airport (ORD) flights

Calendar83Weekly Planes
Duration1h 56mAverage Duration
Ticket$37Cheapest Price
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Comparing Your Travel Options

What companies run services between West Des Moines, IA, USA and Chicago, IL, USA?

American Airlines, United Airlines, and Delta fly from Des Moines (DSM) to Chicago O'Hare International Airport (ORD) every 2 hours. Alternatively, Greyhound USA operates a bus from Des Moines to Chicago Bus Station 3 times a day. Tickets cost $55–90 and the journey takes 7h 5m.

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