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How to get fromWest Des Moines to Milwaukeeby plane, bus (Greyhound, Flixbus), car, bus, or train

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There are 7 ways to get from West Des Moines to Milwaukee by plane, bus (Greyhound, Flixbus), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to General Mitchell International Airport

    best
    1. Fly from Des Moines (DSM) to General Mitchell International Airport (MKE)plane plane DSM - MKE
    4h 3m
    $131–724

  2. Drive 361.6 mi

    cheapest
    1. Drive from West Des Moines to Milwaukeecar car 361.6 mi
    6h 32m
    $66–96

  3. Bus

    1. Take the bus from Des Moines to Chicagobus bus Btw 1202 / ...
    2. Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus bus Greyhound US0150 / ...
    8h 57m

  4. Fly to Chicago O'Hare International Airport, bus

    1. Fly from Des Moines (DSM) to Chicago O'Hare International Airport (ORD)plane plane DSM - ORD
    2. Take the bus from Multi-Modal/Rental Car Facility to Milwaukee Intermodal/Amtrak Stationbus bus
    4h 31m
    $116–497

  5. Bus, train

    1. Take the bus from Des Moines to Chicagobus bus Btw 1202 / ...
    2. Take the train from Chicago Union Station to Milwaukeetrain train Hiawatha Service / ...
    8h 58m

  6. Bus, train via Galesburg

    1. Take the bus from Des Moines to Galesburgbus bus
    2. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Milwaukeetrain train
    11h 3m

  7. Bus via Rochester

    1. Take the bus from Des Moines to Albert Leabus bus
    2. Take the bus from Albert Lea to Rochesterbus bus
    3. Take the bus from Rochester, MN to Milwaukee, WI - Amtrakbus bus
    13h 4m

Des Moines (DSM) to General Mitchell International Airport (MKE) flights

Calendar136Weekly Planes
Duration5h 9mAverage Duration
Ticket$114Cheapest Price
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Questions & Answers

Map of how to get from West Des Moines to Milwaukee.ExpandLaunch map view
  • Distance: 323.2 mi
  • Duration: 4h 3m

What companies run services between West Des Moines, IA, USA and Milwaukee, WI, USA?

Southwest Airlines, Delta, and two other airlines fly from Des Moines (DSM) to General Mitchell International Airport (MKE) hourly. Alternatively, you can take a vehicle from West Des Moines to Milwaukee Intermodal Station via Des Moines and Chicago Bus Station in around 8h 57m.

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