There are 7 ways to get from West Des Moines to Milwaukee by plane, bus (Greyhound, Flixbus), car, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to General Mitchell International Airport
best- Fly from Des Moines (DSM) to General Mitchell International Airport (MKE)plane DSM - MKE
4h 18m$92–486Drive 361.6 mi
cheapest- Drive from West Des Moines to Milwaukeecar 361.6 mi
6h 32m$62–90Bus
- Take the bus from Des Moines to Chicago Bus Stationbus Greyhound US0155S / ...
- Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus Greyhound US0150
10h 54m$96–147Fly to Chicago O'Hare International Airport, bus
- Fly from Des Moines (DSM) to Chicago O'Hare International Airport (ORD)plane DSM - ORD
- Take the bus from Chicago to Milwaukee Intermodal Stationbus
4h 19m$70–300Bus, train
- Take the bus from Des Moines to Chicago Bus Stationbus Greyhound US0155S / ...
- Take the train from Chicago Union Station to Milwaukeetrain Hiawatha Service / ...
10h 58m$127–197Bus, train via Galesburg
- Take the bus from Des Moines to Galesburgbus
- Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Milwaukeetrain
11h 9m$187–302Bus via Milwaukee Mitchell Airport
- Take the bus from Des Moines to Chicago Bus Stationbus Greyhound US0155S / ...
- Take the bus from Chicago Bus Station to Milwaukee Mitchell Airportbus FlixBus 2548 / ...
11h 36m$98–145
Des Moines (DSM) to General Mitchell International Airport (MKE) flights
Comparing Your Travel Options
The cheapest way to get from West Des Moines to Milwaukee is to drive which costs $60 - $90 and takes 6h 32m.
The fastest way to get from West Des Moines to Milwaukee is to fly which takes 4h 18m and costs $90 - $490.
No, there is no direct bus from West Des Moines to Milwaukee station. However, there are services departing from Des Moines and arriving at Milwaukee Intermodal Station via Chicago Bus Station. The journey, including transfers, takes approximately 10h 54m.
The distance between West Des Moines and Milwaukee is 325 miles. The road distance is 363.7 miles.
The best way to get from West Des Moines to Milwaukee without a car is to bus which takes 10h 54m and costs $95 - $150.
It takes approximately 4h 18m to get from West Des Moines to Milwaukee, including transfers.
West Des Moines to Milwaukee bus services, operated by Greyhound USA, depart from Des Moines station.
The best way to get from West Des Moines to Milwaukee is to fly which takes 4h 18m and costs $90 - $490. Alternatively, you can bus, which costs $95 - $150 and takes 10h 54m.
West Des Moines to Milwaukee bus services, operated by Greyhound USA, arrive at Chicago Bus Station.
Yes, the driving distance between West Des Moines to Milwaukee is 364 miles. It takes approximately 6h 32m to drive from West Des Moines to Milwaukee.
What companies run services between West Des Moines, IA, USA and Milwaukee, WI, USA?
United Airlines, American Airlines, and two other airlines fly from Des Moines (DSM) to General Mitchell International Airport (MKE) hourly. Alternatively, you can take a vehicle from West Des Moines to Milwaukee Intermodal Station via Des Moines and Chicago Bus Station in around 10h 54m.
- Website
- united.com
Flights from Des Moines to General Mitchell International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 3h 46m
- When
- Every day
- Estimated price
- $70–460
Flights from Des Moines to General Mitchell International Airport via Denver
- Ave. Duration
- 7h 32m
- When
- Every day
- Estimated price
- $160–750
Flights from Des Moines to Chicago O'Hare International Airport
- Ave. Duration
- 1h 38m
- When
- Every day
- Estimated price
- $35–250
- Website
- delta.com
Flights from Des Moines to General Mitchell International Airport via Minneapolis
- Ave. Duration
- 4h 46m
- When
- Every day
- Estimated price
- $85–500
Flights from Des Moines to General Mitchell International Airport via Atlanta
- Ave. Duration
- 5h 46m
- When
- Every day
- Estimated price
- $150–750
Flights from Des Moines to General Mitchell International Airport via Detroit
- Ave. Duration
- 5h 59m
- When
- Every day
- Estimated price
- $100–600
- Website
- aa.com
Flights from Des Moines to General Mitchell International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 4h 22m
- When
- Every day
- Estimated price
- $70–460
Flights from Des Moines to General Mitchell International Airport via Charlotte
- Ave. Duration
- 6h 23m
- When
- Thursday, Friday, and Sunday
- Estimated price
- $160–750
Flights from Des Moines to Chicago O'Hare International Airport
- Ave. Duration
- 1h 46m
- When
- Every day
- Estimated price
- $35–250
- Website
- southwest.com
Flights from Des Moines to General Mitchell International Airport via Chicago Midway
- Ave. Duration
- 6h 2m
- When
- Every day
- Estimated price
- $75–470
Flights from Des Moines to General Mitchell International Airport via Nashville
- Ave. Duration
- 6h 20m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $120–650
Flights from Des Moines to General Mitchell International Airport via Denver
- Ave. Duration
- 7h 15m
- When
- Every day
- Estimated price
- $160–750
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Chicago Union Station to Milwaukee
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $45–75
- Website
- Amtrak
Train from Galesburg Amtrak Station to Chicago Union Station
- Ave. Duration
- 2h 55m
- Frequency
- 3 times a day
- Estimated price
- $85–140
- Website
- Amtrak
Train from Chicago Union Station to Milwaukee
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $45–75
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Des Moines to Chicago Bus Station
- Ave. Duration
- 8h 5m
- Frequency
- 5 times a day
- Estimated price
- $60–95
- Website
- Greyhound
Bus from Chicago Bus Station to Milwaukee Intermodal Station
- Ave. Duration
- 1h 40m
- Frequency
- Every 4 hours
- Estimated price
- $16–25
- Website
- Greyhound
Bus from Chicago to Milwaukee Intermodal Station
- Ave. Duration
- 1h 20m
- Frequency
- Twice daily
- Estimated price
- $14–22
- Website
- Greyhound
Bus from Des Moines to Chicago Bus Station
- Ave. Duration
- 8h 5m
- Frequency
- 5 times a day
- Estimated price
- $60–95
- Website
- Greyhound
Bus from Des Moines to Galesburg
- Ave. Duration
- 4h 30m
- Frequency
- Twice daily
- Estimated price
- $35–60
- Website
- Greyhound
Bus from Des Moines to Chicago Bus Station
- Ave. Duration
- 8h 5m
- Frequency
- 5 times a day
- Estimated price
- $60–95
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Chicago Bus Station to Milwaukee Intermodal Station
- Ave. Duration
- 1h 55m
- Frequency
- 5 times a day
- Estimated price
- $14–21
- Schedules at
- Flixbus USA
Bus from Chicago Bus Station to Milwaukee Mitchell Airport
- Ave. Duration
- 1h 35m
- Frequency
- 5 times a day
- Estimated price
- $13–20
- Schedules at
- Flixbus USA
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Booking & Getting There
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