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How to get fromWest Des Moines to North Carolinaby plane, bus (Greyhound, Flixbus, Amtrak), bus, train, car, or bus (Greyhound, Flixbus)

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There are 10 ways to get from West Des Moines to North Carolina by plane, bus (Greyhound, Flixbus, Amtrak), bus, train, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Charlotte Douglas International Airport

    best
    1. Fly from Des Moines (DSM) to Charlotte Douglas International Airport (CLT)plane plane DSM - CLT
    3h 15m
    $201–974

  2. Fly to Fayetteville Municipal Airport

    cheapest
    1. Fly from Des Moines (DSM) to Fayetteville Municipal Airport (FAY)plane plane DSM - FAY
    4h 45m
    $164–740

  3. Bus via Carbondale

    1. Take the bus from Des Moines to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Carbondale Intermodal Stationbus bus
    3. Take the bus from Carbondale Intermodal Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Downtown to Charlotte Bus Stationbus bus
    25h 49m
    $206–380

  4. Bus, train

    1. Take the bus from Des Moines to Chicago Bus Stationbus bus
    2. Take the train from Chicago Union Station to Carytrain train
    3. Take the train from Cary to Charlotte Amtrak Stationtrain train
    37h 19m
    $466–985

  5. Drive 1,035.6 mi

    1. Drive from West Des Moines to Charlottecar car 1,035.6 mi
    17h 47m
    $189–273

  6. Fly to Piedmont Triad International Airport

    1. Fly from Des Moines (DSM) to Piedmont Triad International Airport (GSO)plane plane DSM - GSO
    4h 44m
    $256–1,156

  7. Fly to Raleigh-Durham International Airport

    1. Fly from Des Moines (DSM) to Raleigh-Durham International Airport (RDU)plane plane DSM - RDU
    5h 44m
    $181–824

  8. Bus

    1. Take the bus from Des Moines to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Charlotte Bus Stationbus bus
    25h 52m
    $203–377

  9. Bus, train via Ironville

    1. Take the bus from Des Moines to Indianapolis Union Stationbus bus
    2. Take the train from Indianapolis to Ashland Amtrak Stationtrain train
    3. Take the bus from Ashland to Wythevillebus bus
    4. Take the bus from Wytheville to Charlotte Bus Stationbus bus
    26h 20m
    $209–457

  10. Bus, train via Galesburg

    1. Take the bus from Des Moines to Galesburgbus bus
    2. Take the train from Galesburg Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Raleigh Union Stationtrain train
    4. Take the train from Raleigh Union Station to Charlotte Amtrak Stationtrain train
    38h 15m
    $501–1,070

Des Moines (DSM) to Charlotte Douglas International Airport (CLT) flights

Calendar74Weekly Planes
Duration4h 14mAverage Duration
Ticket$188Cheapest Price
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Questions & Answers

Map of how to get from West Des Moines to North Carolina.ExpandLaunch map view
  • Distance: 827.6 mi
  • Duration: 3h 15m

What companies run services between West Des Moines, IA, USA and North Carolina, USA?

American Airlines, Southwest Airlines, and two other airlines fly from Des Moines (DSM) to Charlotte Douglas International Airport (CLT) every 2 hours. Alternatively, you can take a vehicle from West Des Moines to Charlotte Bus Station via Des Moines, St Louis Bus Station, Carbondale Intermodal Station, Atlanta Bus Station, Garnett Station, Civic Center Station, and Atlanta Downtown in around 25h 49m.

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