What is the cheapest way to get from West Des Moines to St. Louis?

The cheapest way to get from West Des Moines to St. Louis is to drive which costs $60 - $90 and takes 6h 46m.

What is the fastest way to get from West Des Moines to St. Louis?

The fastest way to get from West Des Moines to St. Louis is to fly which takes 4h 42m and costs $160 - $850.

Is there a direct bus between West Des Moines and St. Louis?

No, there is no direct bus from West Des Moines to St. Louis station. However, there are services departing from Des Moines and arriving at St Louis Bus Station via . The journey, including transfers, takes approximately 8h 35m.

How far is it from West Des Moines to St. Louis?

The distance between West Des Moines and St. Louis is 282 miles. The road distance is 337.9 miles.

How do I travel from West Des Moines to St. Louis without a car?

The best way to get from West Des Moines to St. Louis without a car is to bus which takes 8h 35m and costs $80 - $150.

How long does it take to get from West Des Moines to St. Louis?

It takes approximately 4h 42m to get from West Des Moines to St. Louis, including transfers.

Where do I catch the West Des Moines to St. Louis bus from?

West Des Moines to St. Louis bus services, operated by Greyhound USA, depart from Des Moines station.

Bus or fly from West Des Moines to St. Louis?

The best way to get from West Des Moines to St. Louis is to fly which takes 4h 42m and costs $160 - $850. Alternatively, you can bus, which costs $80 - $150 and takes 8h 35m.

Where does the West Des Moines to St. Louis bus arrive?

West Des Moines to St. Louis bus services, operated by Greyhound USA, arrive at St Louis Bus Station.

Can I drive from West Des Moines to St. Louis?

Yes, the driving distance between West Des Moines to St. Louis is 338 miles. It takes approximately 6h 46m to drive from West Des Moines to St. Louis.

How do I get a bus ticket from West Des Moines to St. Louis?

Book your West Des Moines to St. Louis bus tickets online with Omio.

Where can I stay near St. Louis?

There are 526+ hotels available in St. Louis.

West Des Moines to St. Louis - 4 ways to travel via plane, bus, and car

How to get fromWest Des Moines to St. Louis

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There are 4 ways to get from West Des Moines to St. Louis by plane, bus (Greyhound), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Fly
best
1. Fly from Des Moines (DSM) to Lambert–St. Louis International Airport (STL)plane DSM - STL
4h 42m
$161–824
Drive 335.9 mi
cheapest
1. Drive from West Des Moines to St. Louiscar 335.9 mi
6h 46m
$62–89
Bus (Greyhound)
1. Take the bus from Des Moines to St Louis Bus Stationbus Greyhound US0153S
8h 35m
$83–147
Bus via Iowa City
1. Take the bus from Des Moines to Iowa Citybus Btw 1208 / ...
2. Take the bus from Iowa City to Saint Louisbus Btw 1489
10h 14m

Des Moines (DSM) to Lambert–St. Louis International Airport (STL) flights

134Weekly Planes

5h 27mAverage Duration

$149Cheapest Price

See schedules

Questions & Answers

Map of how to get from West Des Moines to St. Louis.

Launch map view

Distance: 279.9 mi
Duration: 4h 42m

What companies run services between West Des Moines, IA, USA and St. Louis, MO, USA?

Delta, United Airlines, and two other airlines fly from Des Moines (DSM) to Lambert–St. Louis International Airport (STL) hourly. Alternatively, Greyhound USA operates a bus from Des Moines to St Louis Bus Station once daily. Tickets cost $60–120 and the journey takes 8h 20m.

Airlines

Bus operators

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How to get fromWest Des Moines to St. Louisby plane, bus (Greyhound), car, or bus

There are 4 ways to get from West Des Moines to St. Louis by plane, bus (Greyhound), car, or bus

Fly

Drive 335.9 mi

Bus (Greyhound)

Bus via Iowa City