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How to get fromWest Lafayette to Chicagoby bus, plane, bus (Flixbus, Greyhound), train, car, or taxi

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There are 10 ways to get from West Lafayette to Chicago by bus, plane, bus (Flixbus, Greyhound), train, car, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Cleveland-Hopkins International Airport, fly to Chicago Midway International Airport

    best
    1. Take the bus from Newcomerstown Bus Stop to Cleveland Ohio Greyhound Stationbus bus
    2. Fly from Cleveland-Hopkins International Airport (CLE) to Chicago Midway International Airport (MDW)plane plane CLE - MDW
    6h 17m
    $107–478

  2. Drive 363 mi

    cheapest
    1. Drive from West Lafayette to Chicagocar car 363 mi
    7h 27m
    $67–96

  3. Bus

    1. Take the bus from Newcomerstown to Robert K Pfaff Transit Center - Akronbus bus Charleston
    2. Take the bus from Robert K Pfaff Transit Center - Akron to Chicago Bus Stationbus bus FlixBus N2641
    10h 42m
    $98–197

  4. Bus, train

    1. Take the bus from Newcomerstown Bus Stop to Cleveland Ohio Greyhound Stationbus bus 385
    2. Take the train from Cleveland Amtrak to Chicago Union Stationtrain train Floridian / ...
    10h 55m
    $147–310

  5. Bus to Cleveland-Hopkins International Airport, fly to Chicago O'Hare International Airport

    1. Take the bus from Newcomerstown Bus Stop to Cleveland Ohio Greyhound Stationbus bus
    2. Fly from Cleveland-Hopkins International Airport (CLE) to Chicago O'Hare International Airport (ORD)plane plane CLE - ORD
    6h 42m
    $412–898

  6. Bus to Akron, fly to Chicago O'Hare International Airport

    1. Take the bus from Newcomerstown Bus Stop to Canton Ohio Sarta Transit Stationbus bus
    2. Fly from Akron (CAK) to Chicago O'Hare International Airport (ORD)plane plane CAK - ORD
    6h 7m
    $81–362

  7. Taxi, bus to John Glenn Columbus International Airport, fly to Chicago Midway International Airport

    1. Take the taxi from West Lafayette to Cambridge, OHtaxi taxi
    2. Take the bus from Cambridge, OH to Columbusbus bus
    3. Fly from John Glenn Columbus International Airport (CMH) to Chicago Midway International Airport (MDW)plane plane CMH - MDW
    6h 14m
    $144–536

  8. Taxi, bus to John Glenn Columbus International Airport, fly to Chicago O'Hare International Airport

    1. Take the taxi from West Lafayette to Cambridge, OHtaxi taxi
    2. Take the bus from Cambridge, OH to Columbusbus bus
    3. Fly from John Glenn Columbus International Airport (CMH) to Chicago O'Hare International Airport (ORD)plane plane CMH - ORD
    6h 37m
    $634–1,046

  9. Taxi, bus to Pittsburgh International Airport, fly to Chicago Midway International Airport

    1. Take the taxi from West Lafayette to Cambridge, OHtaxi taxi
    2. Take the bus from Cambridge, OH to Pittsburgh Intermodal Stationbus bus
    3. Fly from Pittsburgh International Airport (PIT) to Chicago Midway International Airport (MDW)plane plane PIT - MDW
    7h 25m
    $147–498

  10. Bus via Cleveland

    1. Take the bus from Newcomerstown Bus Stop to Cleveland Ohio Greyhound Stationbus bus 385
    2. Take the bus from Cleveland to Chicagobus bus Cleveland
    11h 10m
    $79–172

Cleveland-Hopkins International Airport (CLE) to Chicago Midway International Airport (MDW) flights

Calendar33Weekly Planes
Duration1h 27mAverage Duration
Ticket$59Cheapest Price
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Questions & Answers

Map of how to get from West Lafayette to Chicago.ExpandLaunch map view
  • Distance: 440.8 mi
  • Duration: 6h 17m

What companies run services between West Lafayette, OH, USA and Chicago, IL, USA?

You can take a vehicle from West Lafayette to Chicago Bus Station via Newcomerstown and Robert K Pfaff Transit Center - Akron in around 10h 42m.

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