There are 10 ways to get from West Lafayette to Buffalo by bus (Flixbus), bus, train, car, plane, bus (Greyhound), or shuttle
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus (Flixbus)
best- Take the bus from Lafayette Bus Stop to Columbusbus FlixBus 2511 / ...
- Take the bus from Columbus to Buffalobus FlixBus 2526
12h 20m$86–129Bus via Indianapolis
cheapest- Take the bus from Lafayette Bus Stop to Indianapolis Union Stationbus
- Take the bus from Indianapolis Union Station to Columbusbus
- Take the bus from Columbus to Buffalobus
15h 50m$75–146Bus, train
- Take the bus from Lafayette Bus Stop to Chicago Bus Stationbus FlixBus 2511 / ...
- Take the train from Chicago Union Station to Buffalo Depew Stationtrain Lake Shore Limited
15h 8m$310–621Drive 506.5 mi
- Drive from West Lafayette to Buffalocar 506.5 mi
9h 3m$93–134Fly Purdue University Airport to Buffalo Niagara International Airport
- Fly from Purdue University Airport (LAF) to Buffalo Niagara International Airport (BUF)plane LAF - BUF
8h 11m$101–579Shuttle to Indianapolis, fly to Buffalo Niagara International Airport
- Take a shuttle bus from Purdue Mem Union - State Street to Indianapolis Airport
- Fly from Indianapolis (IND) to Buffalo Niagara International Airport (BUF)plane IND - BUF
7h 14m$120–711Bus to Chicago O'Hare International Airport, fly to Buffalo Niagara International Airport
- Take the bus from Purdue Memorial Union to O'Hare Multi-Modal Facilitybus
- Fly from Chicago O'Hare International Airport (ORD) to Buffalo Niagara International Airport (BUF)plane ORD - BUF
6h 24m$231–399Bus to Chicago Midway International Airport, fly to Buffalo Niagara International Airport
- Take the bus from Lafayette Bus Stop to Chicago Bus Stationbus
- Fly from Chicago Midway International Airport (MDW) to Buffalo Niagara International Airport (BUF)plane MDW - BUF
7h 4m$185–374Shuttle to Indianapolis, fly to Toronto Pearson International Airport, bus
- Take a shuttle bus from Purdue Mem Union - State Street to Indianapolis Airport
- Fly from Indianapolis (IND) to Toronto Pearson International Airport (YYZ)plane IND - YYZ
- Take the bus from Toronto Pearson Airport to Buffalobus
9h 17m$89–436Bus to Chicago Midway International Airport, fly to Rochester, bus
- Take the bus from Lafayette Bus Stop to Chicago Bus Stationbus
- Fly from Chicago Midway International Airport (MDW) to Rochester (ROC)plane MDW - ROC
- Take the bus from Rochester Bus Stop to Buffalobus
8h 38m$189–977
West Lafayette to Buffalo by bus (Flixbus)
Comparing Your Travel Options
The cheapest way to get from West Lafayette to Buffalo is to bus which costs $85 - $130 and takes 12h 20m.
The fastest way to get from West Lafayette to Buffalo is to bus and fly which takes 6h 24m and costs $230 - $400.
No, there is no direct bus from West Lafayette to Buffalo. However, there are services departing from Lafayette Bus Stop and arriving at Buffalo via Columbus. The journey, including transfers, takes approximately 12h 20m.
The distance between West Lafayette and Buffalo is 580 miles. The road distance is 509.5 miles.
The best way to get from West Lafayette to Buffalo without a car is to bus which takes 12h 20m and costs $85 - $130.
It takes approximately 12h 20m to get from West Lafayette to Buffalo, including transfers.
West Lafayette to Buffalo bus services, operated by Flixbus USA, depart from Lafayette Bus Stop station.
The best way to get from West Lafayette to Buffalo is to bus which takes 12h 20m and costs $85 - $130. Alternatively, you can fly, which costs $100 - $600 and takes 8h 11m.
West Lafayette to Buffalo bus services, operated by Flixbus USA, arrive at Columbus station.
Yes, the driving distance between West Lafayette to Buffalo is 509 miles. It takes approximately 9h 3m to drive from West Lafayette to Buffalo.
What companies run services between West Lafayette, IN, USA and Buffalo, NY, USA?
You can take a bus from Lafayette Bus Stop to Buffalo via Columbus in around 12h 20m. Alternatively, United Airlines flies from Purdue University Airport (LAF) to Buffalo Niagara International Airport (BUF) 3 times a day.
- Website
- southwest.com
Flights from Indianapolis to Buffalo Niagara International Airport via Chicago Midway International Airport
- Ave. Duration
- 3h 38m
- When
- Sunday, Saturday, Tuesday, and Wednesday
- Estimated price
- $120–700
Flights from Indianapolis to Buffalo Niagara International Airport via Baltimore
- Ave. Duration
- 4h 40m
- When
- Saturday to Wednesday
- Estimated price
- $130–750
Flights from Indianapolis to Buffalo Niagara International Airport via Nashville
- Ave. Duration
- 4h 45m
- When
- Friday
- Estimated price
- $140–750
Flights from Chicago Midway International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 31m
- When
- Every day
- Estimated price
- $100–650
Flights from Chicago Midway International Airport to Rochester
- Ave. Duration
- 1h 42m
- When
- Every day
- Estimated price
- $140–900
Flights from Chicago Midway International Airport to Rochester via Baltimore
- Ave. Duration
- 4h 10m
- When
- Saturday
- Estimated price
- $200–1,100
- Website
- united.com
Flights from Purdue University Airport to Buffalo Niagara International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 8h 1m
- When
- Every day
- Estimated price
- $95–550
Flights from Indianapolis to Buffalo Niagara International Airport via Washington Dulles
- Ave. Duration
- 4h 17m
- When
- Every day
- Estimated price
- $130–750
Flights from Indianapolis to Buffalo Niagara International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 5h 17m
- When
- Every day
- Estimated price
- $120–700
Flights from Chicago O'Hare International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 43m
- When
- Every day
- Estimated price
- $70–430
Flights from Indianapolis to Toronto Pearson International Airport
- Ave. Duration
- 1h 32m
- When
- Every day
- Estimated price
- $60–380
- Website
- aircanada.com
Flights from Indianapolis to Buffalo Niagara International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 5h 17m
- When
- Every day
- Estimated price
- $120–700
Flights from Chicago O'Hare International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 43m
- When
- Every day
- Estimated price
- $70–430
Flights from Indianapolis to Toronto Pearson International Airport
- Ave. Duration
- 1h 32m
- When
- Every day
- Estimated price
- $60–380
- Website
- aa.com
Flights from Indianapolis to Buffalo Niagara International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 4h 13m
- When
- Every day
- Estimated price
- $120–700
Flights from Indianapolis to Buffalo Niagara International Airport via Reagan Washington
- Ave. Duration
- 5h 7m
- When
- Every day
- Estimated price
- $130–750
Flights from Chicago O'Hare International Airport to Buffalo Niagara International Airport
- Ave. Duration
- 1h 45m
- When
- Every day
- Estimated price
- $70–430
- Website
- delta.com
Flights from Indianapolis to Buffalo Niagara International Airport via Detroit
- Ave. Duration
- 4h 28m
- When
- Every day
- Estimated price
- $100–650
Flights from Chicago O'Hare International Airport to Buffalo Niagara International Airport via Detroit
- Ave. Duration
- 3h 52m
- When
- Every day
- Estimated price
- $70–430
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Chicago Union Station to Buffalo Depew Station
- Ave. Duration
- 10h 23m
- Frequency
- Twice daily
- Estimated price
- $290–450
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Lafayette Bus Stop to Columbus
- Ave. Duration
- 4h 55m
- Frequency
- Twice daily
- Estimated price
- $35–55
- Schedules at
- Flixbus USA
Bus from Columbus to Buffalo
- Ave. Duration
- 6h 25m
- Frequency
- Once daily
- Estimated price
- $50–75
- Schedules at
- Flixbus USA
Bus from Lafayette Bus Stop to Chicago Bus Station
- Ave. Duration
- 2h 15m
- Frequency
- Every 4 hours
- Estimated price
- $18–28
- Schedules at
- Flixbus USA
Bus from Lafayette Bus Stop to Chicago Bus Station
- Ave. Duration
- 2h 15m
- Frequency
- Every 4 hours
- Estimated price
- $18–28
- Schedules at
- Flixbus USA
Bus from Toronto Pearson Airport to Buffalo
- Ave. Duration
- 3h 10m
- Frequency
- 5 times a week
- Estimated price
- $14–23
- Schedules at
- Flixbus USA
Bus from Lafayette Bus Stop to Chicago Bus Station
- Ave. Duration
- 2h 15m
- Frequency
- Every 4 hours
- Estimated price
- $18–28
- Schedules at
- Flixbus USA
Bus from Rochester Bus Stop to Buffalo
- Ave. Duration
- 1h 30m
- Frequency
- Every 4 hours
- Estimated price
- $11–17
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Lafayette Bus Stop to Chicago Bus Station
- Ave. Duration
- 3h 15m
- Frequency
- 5 times a day
- Estimated price
- $19–35
- Website
- Greyhound
Bus from Lafayette Bus Stop to Indianapolis Union Station
- Ave. Duration
- 1h 30m
- Frequency
- 3 times a day
- Estimated price
- $10–17
- Website
- Greyhound
Bus from Indianapolis Union Station to Columbus
- Ave. Duration
- 5h 5m
- Frequency
- 3 times a day
- Estimated price
- $29–50
- Website
- Greyhound
Bus from Lafayette Bus Stop to Chicago Bus Station
- Ave. Duration
- 3h 15m
- Frequency
- 5 times a day
- Estimated price
- $19–35
- Website
- Greyhound
Bus from Lafayette Bus Stop to Chicago Bus Station
- Ave. Duration
- 3h 15m
- Frequency
- 5 times a day
- Estimated price
- $19–35
- Website
- Greyhound
Bus from Rochester Bus Stop to Buffalo
- Ave. Duration
- 1h 20m
- Frequency
- 5 times a day
- Estimated price
- $12–19
- Website
- Greyhound
- Phone
- +1 888-378-3823
- [email protected]
- Website
- Barons Bus
Bus from Columbus to Buffalo
- Ave. Duration
- 7h 15m
- Frequency
- Once daily
- Estimated price
- $35–80
- Website
- Barons Bus
- Phone
- +1 800-589-6004
- [email protected]
- Website
- Go Express Travel
Shuttle from Purdue Mem Union - State Street to Indianapolis Airport
- Ave. Duration
- 1h 35m
- Frequency
- On demand
- Estimated price
- $33
- Schedules at
- Go Express Travel
Shuttle from Purdue Mem Union - State Street to Indianapolis Airport
- Ave. Duration
- 1h 35m
- Frequency
- On demand
- Estimated price
- $33
- Schedules at
- Go Express Travel
- Phone
- +1(765)4973828
- Website
- lafayettelimo.com
Shuttle from Purdue Mem Union - State Street to Indianapolis Airport
- Ave. Duration
- 1h 52m
- Frequency
- Every 3 hours
- Estimated price
- $15–28
- Schedules at
- lafayettelimo.com
- Child
- $15–24
- Adult
- $25–28
Shuttle from Purdue Mem Union - State Street to Indianapolis Airport
- Ave. Duration
- 1h 52m
- Frequency
- Every 3 hours
- Estimated price
- $15–28
- Schedules at
- lafayettelimo.com
- Child
- $15–24
- Adult
- $25–28
- Phone
- +1 765-637-5124
- [email protected]
- Website
- Reindeer Shuttle
Bus from Purdue Memorial Union to O'Hare Multi-Modal Facility
- Ave. Duration
- 2h 15m
- Frequency
- 3 times a day
- Estimated price
- $56–75
- Website
- Reindeer Shuttle
- Online Advance
- $56–61
- Walk up Cash
- $65–75
Want to know more about travelling around United States
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Booking & Getting There
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