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How to get fromWest Lafayette to Buffaloby plane, bus (Flixbus), bus, train, car, shuttle, or bus (Greyhound)

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There are 9 ways to get from West Lafayette to Buffalo by plane, bus (Flixbus), bus, train, car, shuttle, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Purdue University Airport to Buffalo Niagara International Airport

    best
    1. Fly from Purdue University Airport (LAF) to Buffalo Niagara International Airport (BUF)plane plane LAF - BUF
    6h 16m
    $106–629

  2. Bus via Indianapolis

    cheapest
    1. Take the bus from Lafayette Bus Stop to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis Union Station to Columbusbus bus
    3. Take the bus from Columbus to Buffalobus bus
    15h 50m
    $76–147

  3. Bus (Flixbus)

    1. Take the bus from Lafayette Bus Stop to Columbusbus bus FlixBus 2511 / ...
    2. Take the bus from Columbus to Buffalobus bus FlixBus 2526
    12h 20m
    $88–136

  4. Bus, train

    1. Take the bus from Lafayette Bus Stop to Chicago Bus Stationbus bus FlixBus 2511 / ...
    2. Take the train from Chicago Union Station to Buffalo Depew Stationtrain train Lake Shore Limited
    15h 8m
    $311–622

  5. Drive  506.5 mi

    1. Drive from West Lafayette to Buffalocar car 506.5 mi
    9h 3m
    $93–134

  6. Shuttle to Indianapolis, fly to Buffalo Niagara International Airport

    1. Take a shuttle bus from Purdue Mem Union - State Street to Indianapolis Airportshuttle bus
    2. Fly from Indianapolis (IND) to Buffalo Niagara International Airport (BUF)plane plane IND - BUF
    7h 14m
    $120–711

  7. Bus to Chicago O'Hare International Airport, fly to Buffalo Niagara International Airport

    1. Take the bus from Purdue Memorial Union to O'Hare Multi-Modal Facilitybus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Buffalo Niagara International Airport (BUF)plane plane ORD - BUF
    6h 24m
    $231–399

  8. Bus to Chicago Midway International Airport, fly to Buffalo Niagara International Airport

    1. Take the bus from Lafayette Bus Stop to Chicago Bus Stationbus bus
    2. Fly from Chicago Midway International Airport (MDW) to Buffalo Niagara International Airport (BUF)plane plane MDW - BUF
    7h 4m
    $186–435

  9. Shuttle to Indianapolis, fly to Toronto Pearson International Airport, bus

    1. Take a shuttle bus from Purdue Mem Union - State Street to Indianapolis Airportshuttle bus
    2. Fly from Indianapolis (IND) to Toronto Pearson International Airport (YYZ)plane plane IND - YYZ
    3. Take the bus from Toronto Pearson Airport to Buffalobus bus
    9h 17m
    $90–436

West Lafayette to Buffalo by bus (Flixbus)

Calendar7Weekly Buses
Duration12h 20mAverage Duration
Ticket$88Cheapest Price
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Comparing Your Travel Options

Map of how to get from West Lafayette to Buffalo.ExpandLaunch map view
  • Distance: 468.7 mi
  • Duration: 6h 16m

What companies run services between West Lafayette, IN, USA and Buffalo, NY, USA?

United Airlines flies from Purdue University Airport (LAF) to Buffalo Niagara International Airport (BUF) once daily. Alternatively, you can take a bus from Lafayette Bus Stop to Buffalo via Columbus in around 12h 20m.

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