Rome2Rio

How to get fromWest Lafayette to Cape Girardeauby bus, plane, bus (Greyhound), train, taxi, or car

Find Transport to Cape Girardeau

See all options

There are 10 ways to get from West Lafayette to Cape Girardeau by bus, plane, bus (Greyhound), train, taxi, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Chicago O'Hare International Airport, fly to Cape Girardeau Municipal Airport

    best
    1. Take the bus from Purdue Memorial Union to O'Hare Multi-Modal Facilitybus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Cape Girardeau Municipal Airport (CGI)plane plane ORD - CGI
    5h 22m
    $174–319

  2. Drive 315.6 mi

    cheapest
    1. Drive from West Lafayette to Cape Girardeaucar car 315.6 mi
    6h 4m
    $58–84

  3. Bus (Greyhound)

    1. Take the bus from Lafayette Bus Stop to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis Union Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    9h 34m
    $69–132

  4. Train, taxi

    1. Take the train from Lafayette Amtrak Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Carbondaletrain train
    3. Take the taxi from Carbondale to Cape Girardeautaxi taxi
    10h 54m
    $233–419

  5. Bus to Chicago O'Hare International Airport, fly to Williamson County Regional Airport, taxi

    1. Take the bus from Purdue Memorial Union to O'Hare Multi-Modal Facilitybus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Williamson County Regional Airport (MWA)plane plane ORD - MWA
    3. Take the taxi from Williamson County Regional Airport (MWA) to Cape Girardeautaxi taxi
    6h 3m
    $266–451

  6. Bus to Chicago O'Hare International Airport, fly to Barkley Regional Airport, taxi

    1. Take the bus from Purdue Memorial Union to O'Hare Multi-Modal Facilitybus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Barkley Regional Airport (PAH)plane plane ORD - PAH
    3. Take the taxi from Barkley Regional Airport (PAH) to Cape Girardeautaxi taxi
    6h 29m
    $241–551

  7. Fly Purdue University Airport to Cape Girardeau Municipal Airport

    1. Fly from Purdue University Airport (LAF) to Cape Girardeau Municipal Airport (CGI)plane plane LAF - CGI
    9h 49m
    $164–579

  8. Bus to Chicago O'Hare International Airport, fly to Lambert–St. Louis International Airport, bus

    1. Take the bus from Purdue Memorial Union to O'Hare Multi-Modal Facilitybus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Lambert–St. Louis International Airport (STL)plane plane ORD - STL
    3. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    8h 36m
    $353–818

  9. Fly Purdue University Airport to Williamson County Regional Airport, taxi

    1. Fly from Purdue University Airport (LAF) to Williamson County Regional Airport (MWA)plane plane LAF - MWA
    2. Take the taxi from Williamson County Regional Airport (MWA) to Cape Girardeautaxi taxi
    7h 50m
    $181–481

  10. Train, bus

    1. Take the train from Lafayette Amtrak Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to St. Louistrain train
    3. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    12h 19m
    $147–313

Chicago O'Hare International Airport (ORD) to Cape Girardeau Municipal Airport (CGI) flights

Calendar7Weekly Planes
Duration1h 40mAverage Duration
Ticket$99Cheapest Price
See schedules

Questions & Answers

Map of how to get from West Lafayette to Cape Girardeau.ExpandLaunch map view
  • Distance: 488.8 mi
  • Duration: 5h 22m

What companies run services between West Lafayette, IN, USA and Cape Girardeau, MO, USA?

You can take a bus from Lafayette Bus Stop to Cape Girardeau via Indianapolis Union Station, St Louis Bus Station, and Cape Girardeau in around 9h 34m. Alternatively, United Airlines and Corporate Flight Management Inc fly from Purdue University Airport (LAF) to Cape Girardeau Municipal Airport (CGI) 3 times a day.

Airlines
Train operators
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers