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How to get fromWest Lafayette to Carlisleby plane, bus (Flixbus), car, bus, shuttle, train, or bus (Greyhound)

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There are 7 ways to get from West Lafayette to Carlisle by plane, bus (Flixbus), car, bus, shuttle, train, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Purdue University Airport to Harrisburg International Airport

    best
    1. Fly from Purdue University Airport (LAF) to Harrisburg International Airport (MDT)plane plane LAF - MDT
    8h 6m
    $78–405

  2. Bus (Flixbus)

    1. Take the bus from Lafayette Bus Stop to Harrisburg Bus Stationbus bus FlixBus N2642 / ...
    15h 6m
    $98–157

  3. Drive 584.8 mi

    1. Drive from West Lafayette to Carlislecar car 584.8 mi
    10h 15m
    $107–155

  4. Bus to Chicago O'Hare International Airport, fly to Harrisburg International Airport

    1. Take the bus from Purdue Memorial Union to O'Hare Multi-Modal Facilitybus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Harrisburg International Airport (MDT)plane plane ORD - MDT
    8h
    $118–425

  5. Shuttle to Indianapolis, fly to Philadelphia International Airport, train

    1. Take a shuttle bus from Purdue Mem Union - State Street to Indianapolis Airportshuttle bus
    2. Fly from Indianapolis (IND) to Philadelphia International Airport (PHL)plane plane IND - PHL
    3. Take the train from 30th Street Station to Harrisburgtrain train
    9h 48m
    $159–903

  6. Bus to Chicago O'Hare International Airport, fly to Penn State University Park Airport, bus

    1. Take the bus from Purdue Memorial Union to O'Hare Multi-Modal Facilitybus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Penn State University Park Airport (SCE)plane plane ORD - SCE
    3. Take the bus from State College Regional Airport to Harrisburg Bus Stationbus bus
    9h 59m
    $125–436

  7. Bus via Indianapolis (Greyhound)

    1. Take the bus from Lafayette Bus Stop to Indianapolis Union Stationbus bus Greyhound US0120S / ...
    2. Take the bus from Indianapolis Union Station to Harrisburg Bus Stationbus bus Greyhound US0421
    18h 41m
    $91–180

West Lafayette to Carlisle by bus and foot (Flixbus)

Calendar10Weekly Services
Duration15h 6mAverage Duration
Ticket$98Cheapest Price
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Questions & Answers

Map of how to get from West Lafayette to Carlisle.ExpandLaunch map view
  • Distance: 568.5 mi
  • Duration: 8h 6m

What companies run services between West Lafayette, IN, USA and Carlisle, PA, USA?

United Airlines flies from Purdue University Airport (LAF) to Harrisburg International Airport (MDT) 4 times a day. Alternatively, Flixbus USA operates a bus from Lafayette Bus Stop to Harrisburg Bus Station once daily. Tickets cost $95–160 and the journey takes 13h 15m.

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