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How to get fromWest Lafayette to Charlestonby shuttle, plane, bus (Flixbus, Greyhound), train (Amtrak), car, or bus

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There are 8 ways to get from West Lafayette to Charleston by shuttle, plane, bus (Flixbus, Greyhound), train (Amtrak), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Shuttle to Indianapolis, fly

    best
    1. Take a shuttle bus from Purdue Mem Union - State Street to Indianapolis Airportshuttle bus
    2. Fly from Indianapolis (IND) to Charleston International Airport (CHS)plane plane IND - CHS
    7h 48m
    $102–505

  2. Fly from Purdue University Airport

    cheapest
    1. Fly from Purdue University Airport (LAF) to Charleston International Airport (CHS)plane plane LAF - CHS
    7h 52m
    $93–443

  3. Bus

    1. Take the bus from Lafayette Bus Stop to Atlanta Bus Stationbus bus FlixBus 2512
    2. Take the bus from Atlanta Bus Station to Charleston Bus Stationbus bus Greyhound US0641S
    26h 49m
    $169–322

  4. Train (Amtrak)

    1. Take the train from Lafayette Amtrak Station to Alexandriatrain train Cardinal
    2. Take the train from Alexandria to Charleston Amtrak Stationtrain train Silver Meteor / ...
    30h 47m
    $430–886

  5. Drive 756.9 mi

    1. Drive from West Lafayette to Charlestoncar car 756.9 mi
    14h
    $139–200

  6. Bus to Chicago O'Hare International Airport, fly

    1. Take the bus from Purdue Memorial Union to O'Hare Multi-Modal Facilitybus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Charleston International Airport (CHS)plane plane ORD - CHS
    7h 24m
    $138–483

  7. Bus to Chicago Midway International Airport, fly

    1. Take the bus from Lafayette Bus Stop to Chicagobus bus
    2. Fly from Chicago Midway International Airport (MDW) to Charleston International Airport (CHS)plane plane MDW - CHS
    7h 52m
    $123–595

  8. Bus to Covington, fly

    1. Take the bus from Lafayette Bus Stop to Cincinnatibus bus
    2. Fly from Covington (CVG) to Charleston International Airport (CHS)plane plane CVG - CHS
    8h 57m
    $112–1,052

West Lafayette to Charleston by bus

Calendar14Weekly Buses
Duration26h 49mAverage Duration
Ticket$169Cheapest Price
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Questions & Answers

Map of how to get from West Lafayette to Charleston.ExpandLaunch map view
  • Distance: 670.2 mi
  • Duration: 7h 48m

What companies run services between West Lafayette, IN, USA and Charleston, SC, USA?

You can take a bus from Lafayette Bus Stop to Transit Mall via Atlanta Bus Station, Charleston Bus Station, North Charleston Transit Center, N. Charleston SuperStop, and Rivers Ave / Cosgrove Ave in around 26h 49m. Alternatively, you can take a train from Lafayette Amtrak Station to Charleston via Alexandria and Charleston Amtrak Station in around 30h 47m.

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