There are 11 ways to get from West Lafayette to Durham by shuttle, plane, bus (Flixbus, Greyhound), train (Amtrak), car, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Shuttle to Indianapolis, fly to Raleigh-Durham International Airport
best- Take a shuttle bus from Purdue Mem Union - State Street to Indianapolis Airport
- Fly from Indianapolis (IND) to Raleigh-Durham International Airport (RDU)plane IND - RDU
5h 53m$106–519Fly Purdue University Airport to Raleigh-Durham International Airport
cheapest- Fly from Purdue University Airport (LAF) to Raleigh-Durham International Airport (RDU)plane LAF - RDU
7h 36m$97–457Bus
- Take the bus from Lafayette Bus Stop to Columbusbus
- Take the bus from Columbus to Winston Salem(Trans Center)bus
- Take the bus from Winston Salem(Trans Center) to Durhambus
18h 33m$188–274Train (Amtrak)
- Take the train from Lafayette Amtrak Station to Charlottesvilletrain
- Take the train from Charlottesville to Greensborotrain
- Take the train from Greensboro to Durham Amtrak Stationtrain
24h 13m$294–605Drive 650.5 mi
- Drive from West Lafayette to Durhamcar 650.5 mi
11h 35m$119–172Bus to Chicago O'Hare International Airport, fly to Raleigh-Durham International Airport
- Take the bus from Pmu to ORD Airportbus
- Fly from Chicago O'Hare International Airport (ORD) to Raleigh-Durham International Airport (RDU)plane ORD - RDU
6h 37m$242–577Bus to Chicago Midway International Airport, fly to Raleigh-Durham International Airport
- Take the bus from Lafayette Bus Stop to Chicagobus
- Fly from Chicago Midway International Airport (MDW) to Raleigh-Durham International Airport (RDU)plane MDW - RDU
7h 47m$178–351Bus to Chicago O'Hare International Airport, fly to Piedmont Triad International Airport, train
- Take the bus from Pmu to ORD Airportbus
- Fly from Chicago O'Hare International Airport (ORD) to Piedmont Triad International Airport (GSO)plane ORD - GSO
- Take the train from Greensboro to Durham Amtrak Stationtrain
7h 24m$212–746Bus to Covington, fly to Raleigh-Durham International Airport
- Take the bus from Lafayette Bus Stop to Cincinnatibus
- Fly from Covington (CVG) to Raleigh-Durham International Airport (RDU)plane CVG - RDU
8h 44m$267–518Train via Arlington (Amtrak)
- Take the train from Lafayette Amtrak Station to Alexandriatrain Cardinal
- Take the train from Alexandria to Durham Amtrak Stationtrain Carolinian
28h 3m$356–733Bus, train (Amtrak)
- Take the bus from Lafayette Amtrak Station to Chicago Union Stationbus
- Take the train from Chicago Union Station to Carytrain Floridian
29h 33m$380–800
West Lafayette to Durham by bus and foot
Questions & Answers
The cheapest way to get from West Lafayette to Durham is to drive which costs $110 - $180 and takes 11h 35m.
The fastest way to get from West Lafayette to Durham is to shuttle and fly which takes 5h 53m and costs $100 - $550.
No, there is no direct bus from West Lafayette to Durham. However, there are services departing from Lafayette Bus Stop and arriving at Durham via E Main St & S 5Th St, Columbus and Winston Salem(Trans Center). The journey, including transfers, takes approximately 18h 33m.
No, there is no direct train from West Lafayette station to Durham station. However, there are services departing from Lafayette Amtrak Station and arriving at Durham Amtrak Station via Charlottesville and Greensboro. The journey, including transfers, takes approximately 24h 13m.
The distance between West Lafayette and Durham is 578 miles. The road distance is 654.3 miles.
The best way to get from West Lafayette to Durham without a car is to bus which takes 18h 33m and costs $180 - $280.
It takes approximately 5h 53m to get from West Lafayette to Durham, including transfers.
West Lafayette to Durham bus services, operated by Flixbus USA, depart from Lafayette Bus Stop station.
West Lafayette to Durham train services, operated by Amtrak, depart from Lafayette Amtrak Station.
The best way to get from West Lafayette to Durham is to bus which takes 18h 33m and costs $180 - $280. Alternatively, you can train, which costs $290 - $650 and takes 24h 13m, you could also fly, which costs $95 - $460 and takes 7h 36m.
What companies run services between West Lafayette, IN, USA and Durham, NC, USA?
You can take a bus from Lafayette Bus Stop to Durham via Columbus, E Main St & S 5Th St, S Grant Ave & E Mound St, Columbus, and Winston Salem(Trans Center) in around 18h 33m. Alternatively, you can take a train from Lafayette Amtrak Station to Durham Amtrak Station via Charlottesville and Greensboro in around 24h 13m.
- Website
- southwest.com
Flights from Indianapolis to Raleigh-Durham International Airport via Nashville
- Ave. Duration
- 3h 40m
- When
- Monday to Wednesday
- Estimated price
- $100–550
Flights from Indianapolis to Raleigh-Durham International Airport via Baltimore
- Ave. Duration
- 3h 48m
- When
- Saturday, Tuesday, and Wednesday
- Estimated price
- $110–600
Flights from Indianapolis to Raleigh-Durham International Airport via Chicago Midway International Airport
- Ave. Duration
- 3h 51m
- When
- Saturday, Sunday, Tuesday, and Wednesday
- Estimated price
- $110–600
Flights from Chicago Midway International Airport to Raleigh-Durham International Airport
- Ave. Duration
- 1h 55m
- When
- Every day
- Estimated price
- $100–550
Flights from Covington to Raleigh-Durham International Airport via Nashville
- Ave. Duration
- 3h 40m
- When
- Saturday, Tuesday, and Wednesday
- Estimated price
- $110–600
Flights from Covington to Raleigh-Durham International Airport via Baltimore
- Ave. Duration
- 3h 40m
- When
- Monday, Thursday, and Friday
- Estimated price
- $110–600
- Website
- united.com
Flights from Indianapolis to Raleigh-Durham International Airport via Washington Dulles
- Ave. Duration
- 3h 57m
- When
- Every day
- Estimated price
- $100–550
Flights from Purdue University Airport to Raleigh-Durham International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 5h 50m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $90–450
Flights from Chicago O'Hare International Airport to Raleigh-Durham International Airport
- Ave. Duration
- 2h 16m
- When
- Every day
- Estimated price
- $80–410
Flights from Chicago O'Hare International Airport to Piedmont Triad International Airport
- Ave. Duration
- 2h 5m
- When
- Every day
- Estimated price
- $110–600
Flights from Chicago O'Hare International Airport to Piedmont Triad International Airport via Washington Dulles
- Ave. Duration
- 4h 28m
- When
- Every day
- Estimated price
- $130–700
Flights from Covington to Raleigh-Durham International Airport via Washington Dulles
- Ave. Duration
- 3h 43m
- When
- Saturday
- Estimated price
- $110–600
- Website
- aa.com
Flights from Indianapolis to Raleigh-Durham International Airport via Charlotte
- Ave. Duration
- 3h 33m
- When
- Every day
- Estimated price
- $90–500
Flights from Chicago O'Hare International Airport to Raleigh-Durham International Airport
- Ave. Duration
- 2h 13m
- When
- Every day
- Estimated price
- $80–410
Flights from Chicago O'Hare International Airport to Piedmont Triad International Airport
- Ave. Duration
- 2h 2m
- When
- Every day
- Estimated price
- $110–600
Flights from Chicago O'Hare International Airport to Piedmont Triad International Airport via Charlotte
- Ave. Duration
- 4h 15m
- When
- Every day
- Estimated price
- $120–650
Flights from Covington to Raleigh-Durham International Airport via Charlotte
- Ave. Duration
- 3h 27m
- When
- Every day
- Estimated price
- $95–550
- Website
- delta.com
Flights from Indianapolis to Raleigh-Durham International Airport
- Ave. Duration
- 1h 50m
- When
- Every day
- Estimated price
- $85–480
Flights from Indianapolis to Raleigh-Durham International Airport via Atlanta
- Ave. Duration
- 4h 2m
- When
- Every day
- Estimated price
- $110–600
Flights from Indianapolis to Raleigh-Durham International Airport via Detroit
- Ave. Duration
- 4h 2m
- When
- Every day
- Estimated price
- $110–550
Flights from Chicago O'Hare International Airport to Piedmont Triad International Airport via Atlanta
- Ave. Duration
- 4h 26m
- When
- Every day
- Estimated price
- $140–700
Flights from Covington to Raleigh-Durham International Airport
- Ave. Duration
- 1h 30m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $85–500
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Lafayette Amtrak Station to Charlottesville
- Ave. Duration
- 17h 39m
- Frequency
- 3 times a week
- Estimated price
- $220–450
- Website
- https://www.amtrak.com/home.html
Train from Charlottesville to Greensboro
- Ave. Duration
- 3h 33m
- Frequency
- Once daily
- Estimated price
- $55–120
- Website
- https://www.amtrak.com/home.html
Train from Greensboro to Durham Amtrak Station
- Ave. Duration
- 1h 1m
- Frequency
- 5 times a day
- Estimated price
- $17–40
- Website
- https://www.amtrak.com/home.html
Train from Greensboro to Durham Amtrak Station
- Ave. Duration
- 1h 1m
- Frequency
- 5 times a day
- Estimated price
- $17–40
- Website
- https://www.amtrak.com/home.html
Train from Lafayette Amtrak Station to Alexandria
- Ave. Duration
- 20h 31m
- Frequency
- 3 times a week
- Estimated price
- $250–550
- Website
- https://www.amtrak.com/home.html
Train from Alexandria to Durham Amtrak Station
- Ave. Duration
- 6h 32m
- Frequency
- Once daily
- Estimated price
- $100–220
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Cary
- Ave. Duration
- 24h 26m
- Frequency
- Once daily
- Estimated price
- $350–750
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 800-589-6004
- [email protected]
- Website
- goexpresstravel.com
Shuttle from Purdue Mem Union - State Street to Indianapolis Airport
- Ave. Duration
- 1h 35m
- Frequency
- On demand
- Estimated price
- $33
- Schedules at
- goexpresstravel.com
- Phone
- +1(765)4973828
- Website
- lafayettelimo.com
Shuttle from Purdue Mem Union - State Street to Indianapolis Airport
- Ave. Duration
- 1h 52m
- Frequency
- Every 3 hours
- Estimated price
- $15–28
- Schedules at
- lafayettelimo.com
- Child
- $15–24
- Adult
- $25–28
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Lafayette Bus Stop to Columbus
- Ave. Duration
- 4h 55m
- Frequency
- Twice daily
- Estimated price
- $35–65
- Schedules at
- flixbus.com
Bus from Lafayette Bus Stop to Chicago
- Ave. Duration
- 2h 10m
- Frequency
- 3 times a day
- Estimated price
- $18–30
- Schedules at
- flixbus.com
Bus from Lafayette Bus Stop to Cincinnati
- Ave. Duration
- 3h 25m
- Frequency
- Twice daily
- Estimated price
- $28–50
- Schedules at
- flixbus.com
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Lafayette Bus Stop to Columbus
- Ave. Duration
- 4h 55m
- Frequency
- Twice daily
- Estimated price
- $60–90
- Book at
- https://www.jeffersonlines.com
- Adult
- $60–90
Bus from Columbus to Winston Salem(Trans Center)
- Ave. Duration
- 9h 25m
- Frequency
- Once daily
- Estimated price
- $95–140
- Book at
- https://www.jeffersonlines.com
- Adult
- $95–140
Bus from Winston Salem(Trans Center) to Durham
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- $29–45
- Book at
- https://www.jeffersonlines.com
- Adult
- $29–45
Bus from Lafayette Bus Stop to Chicago
- Ave. Duration
- 2h 25m
- Frequency
- 5 times a day
- Estimated price
- $35–50
- Book at
- https://www.jeffersonlines.com
- Adult
- $35–50
Bus from Lafayette Bus Stop to Cincinnati
- Ave. Duration
- 3h 25m
- Frequency
- Once daily
- Estimated price
- $45–70
- Book at
- https://www.jeffersonlines.com
- Adult
- $45–70
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Columbus to Winston Salem(Trans Center)
- Ave. Duration
- 9h 20m
- Frequency
- Once daily
- Estimated price
- $65–130
- Website
- https://www.greyhound.com/
Bus from Winston Salem(Trans Center) to Durham
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- $13–25
- Website
- https://www.greyhound.com/
Bus from Lafayette Bus Stop to Chicago
- Ave. Duration
- 2h 25m
- Frequency
- Once daily
- Estimated price
- $18–35
- Website
- https://www.greyhound.com/
- Phone
- +1 765-637-5124
- [email protected]
- Website
- reindeershuttle.com
Bus from Pmu to ORD Airport
- Ave. Duration
- 2h
- Frequency
- Twice daily
- Estimated price
- $56–75
- Website
- https://www.reindeershuttle.com
- Online Advance
- $56–61
- Walk up Cash
- $65–75
Bus from Pmu to ORD Airport
- Ave. Duration
- 2h
- Frequency
- Twice daily
- Estimated price
- $56–75
- Website
- https://www.reindeershuttle.com
- Online Advance
- $56–61
- Walk up Cash
- $65–75
Rome2Rio's guide to Amtrak Thruway
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Lafayette Amtrak Station to Chicago Union Station
- Ave. Duration
- 2h 20m
- Frequency
- Twice daily
- Estimated price
- $24–45
- Website
- https://www.amtrak.com/home.html
- Adult
- $24–45
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
West Lafayette to Durham bus services, operated by Flixbus USA, arrive at Columbus station.
West Lafayette to Durham train services, operated by Amtrak, arrive at Charlottesville station.
Yes, the driving distance between West Lafayette to Durham is 654 miles. It takes approximately 11h 35m to drive from West Lafayette to Durham.
Book your West Lafayette to Durham train tickets online with Omio.
Book your West Lafayette to Durham bus tickets online with Omio and FlixBus.
There are 404+ hotels available in Durham.












