Rome2Rio

How to get fromWest Lafayette to Durhamby shuttle, plane, bus (Flixbus, Greyhound), train (Amtrak), car, bus, or train

Find Transport to Durham

See all options

There are 10 ways to get from West Lafayette to Durham by shuttle, plane, bus (Flixbus, Greyhound), train (Amtrak), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Shuttle to Indianapolis, fly to Raleigh-Durham International Airport

    best
    1. Take a shuttle bus from Purdue Mem Union - State Street to Indianapolis Airportshuttle bus
    2. Fly from Indianapolis (IND) to Raleigh-Durham International Airport (RDU)plane plane IND - RDU
    5h 46m
    $181–409

  2. Fly Purdue University Airport to Raleigh-Durham International Airport

    cheapest
    1. Fly from Purdue University Airport (LAF) to Raleigh-Durham International Airport (RDU)plane plane LAF - RDU
    7h 48m
    $97–497

  3. Bus

    1. Take the bus from Lafayette Bus Stop to Columbusbus bus
    2. Take the bus from Columbus to Winston Salem(Trans Center)bus bus
    3. Take the bus from Winston Salem(Trans Center) to Durhambus bus
    18h 33m
    $115–186

  4. Train via Charlottesville (Amtrak)

    1. Take the train from Lafayette Amtrak Station to Charlottesvilletrain train
    2. Take the train from Charlottesville to Greensborotrain train
    3. Take the train from Greensboro to Durham Amtrak Stationtrain train
    24h 13m
    $230–522

  5. Drive  650.5 mi

    1. Drive from West Lafayette to Durhamcar car 650.5 mi
    11h 35m
    $119–172

  6. Bus to Chicago O'Hare International Airport, fly to Raleigh-Durham International Airport

    1. Take the bus from Purdue Memorial Union to O'Hare Multi-Modal Facilitybus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Raleigh-Durham International Airport (RDU)plane plane ORD - RDU
    7h 1m
    $232–827

  7. Bus to Chicago Midway International Airport, fly to Raleigh-Durham International Airport

    1. Take the bus from Lafayette Bus Stop to Chicagobus bus
    2. Fly from Chicago Midway International Airport (MDW) to Raleigh-Durham International Airport (RDU)plane plane MDW - RDU
    7h 37m
    $177–264

  8. Bus to Chicago O'Hare International Airport, fly to Piedmont Triad International Airport, train

    1. Take the bus from Purdue Memorial Union to O'Hare Multi-Modal Facilitybus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Piedmont Triad International Airport (GSO)plane plane ORD - GSO
    3. Take the train from Greensboro to Durham Amtrak Stationtrain train
    7h 44m
    $209–791

  9. Train, bus

    1. Take the train from Lafayette Amtrak Station to Ashland Amtrak Stationtrain train
    2. Take the bus from Ashland Bus Station to Winston Salem(Trans Center)bus bus
    3. Take the bus from Coble Transportation Center to N Columbia St at W Franklin Stbus bus 4
    21h 42m
    $143–280

  10. Train (Amtrak)

    1. Take the train from Lafayette Amtrak Station to Chicago Union Stationtrain train Cardinal
    2. Take the train from Chicago Union Station to Raleigh Union Stationtrain train Floridian
    30h 3m
    $304–721

West Lafayette to Durham by bus and foot

Calendar7Weekly Services
Duration18h 33mAverage Duration
Ticket$115Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from West Lafayette to Durham.ExpandLaunch map view
  • Distance: 574.2 mi
  • Duration: 5h 46m

What companies run services between West Lafayette, IN, USA and Durham, NC, USA?

You can take a bus from Lafayette Bus Stop to Durham via Columbus, E Main St & S 5Th St, S Grant Ave & E Mound St, Columbus, and Winston Salem(Trans Center) in around 18h 33m. Alternatively, you can take a train from Lafayette Amtrak Station to Durham Amtrak Station via Charlottesville and Greensboro in around 24h 13m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There