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How to get fromWest Lafayette to Hannibalby bus, train, car, plane, taxi, or train (Amtrak)

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There are 6 ways to get from West Lafayette to Hannibal by bus, train, car, plane, taxi, or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, train via Chicago (Amtrak)

    best
    1. Take the bus from Lafayette Amtrak Station to Chicago Union Stationbus bus Nashville
    2. Take the train from Chicago Union Station to Quincy Amtrak Stationtrain train Carl Sandburg / ...
    8h 11m
    $244–384

  2. Drive  279.8 mi

    cheapest
    1. Drive from West Lafayette to Hannibalcar car 279.8 mi
    4h 43m
    $48–70

  3. Bus, train

    1. Take the bus from Lafayette Bus Stop to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis Union Station to Galesburgbus bus
    3. Take the train from Galesburg Amtrak Station to Quincy Amtrak Stationtrain train
    10h 8m
    $197–297

  4. Bus, fly, taxi

    1. Take the bus from Purdue Memorial Union to O'Hare Multi-Modal Facilitybus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Quincy Regional Airport (UIN)plane plane ORD - UIN
    3. Take the taxi from Quincy Regional Airport (UIN) to Hannibaltaxi taxi
    5h 25m
    $216–441

  5. Bus, train via Chicago #2

    1. Take the bus from Lafayette Bus Stop to Chicago Bus Stationbus bus FlixBus 2515 / ...
    2. Take the train from Chicago Union Station to Quincy Amtrak Stationtrain train Carl Sandburg / ...
    8h 15m
    $240–373

  6. Train (Amtrak)

    1. Take the train from Lafayette Amtrak Station to Chicago Union Stationtrain train Cardinal
    2. Take the train from Chicago Union Station to Quincy Amtrak Stationtrain train Carl Sandburg / ...
    9h 15m
    $287–442

Chicago O'Hare International Airport (ORD) to Quincy Regional Airport (UIN) flights

Calendar7Weekly Planes
Duration1h 25mAverage Duration
Ticket$88Cheapest Price
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Comparing Your Travel Options

Map of how to get from West Lafayette to Hannibal.ExpandLaunch map view
  • Distance: 450.8 mi
  • Duration: 8h 11m

What companies run services between West Lafayette, IN, USA and Hannibal, MO, USA?

You can take a train from Lafayette Amtrak Station to Hannibal via Chicago Union Station and Quincy Amtrak Station in around 9h 15m.

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