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How to get fromWest Lafayette to Jefferson Cityby bus, train, bus (Greyhound), car, plane, train (Amtrak), or shuttle

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There are 8 ways to get from West Lafayette to Jefferson City by bus, train, bus (Greyhound), car, plane, train (Amtrak), or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, train (Amtrak)

    best
    1. Take the bus from Lafayette Amtrak Station to Chicago Union Stationbus bus
    2. Take the train from Chicago Union Station to Jefferson City Stationtrain train Lincoln Service Missouri River Runner
    11h 6m
    $144–314

  2. Drive 370.2 mi

    cheapest
    1. Drive from West Lafayette to Jefferson Citycar car 370.2 mi
    6h 33m
    $68–98

  3. Bus (Greyhound)

    1. Take the bus from Lafayette Bus Stop to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis Union Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Jefferson Citybus bus
    11h 33m
    $78–149

  4. Fly from Purdue University Airport

    1. Fly from Purdue University Airport (LAF) to Columbia Regional Airport (COU)plane plane LAF - COU
    7h 23m
    $146–441

  5. Bus, train via Chicago

    1. Take the bus from Lafayette Bus Stop to Chicago Bus Stationbus bus FlixBus 2511 / ...
    2. Take the train from Chicago Union Station to Jefferson City Stationtrain train Lincoln Service Missouri River Runner
    11h 10m
    $138–304

  6. Train (Amtrak)

    1. Take the train from Lafayette Amtrak Station to Chicago Union Stationtrain train Cardinal
    2. Take the train from Chicago Union Station to Jefferson City Stationtrain train Lincoln Service Missouri River Runner
    12h 10m
    $158–349

  7. Bus to Chicago O'Hare International Airport, fly

    1. Take the bus from Purdue Memorial Union to O'Hare Multi-Modal Facilitybus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Columbia Regional Airport (COU)plane plane ORD - COU
    5h 23m
    $191–481

  8. Shuttle to Indianapolis, fly

    1. Take a shuttle bus from Purdue Mem Union - State Street to Indianapolis Airportshuttle bus
    2. Fly from Indianapolis (IND) to Columbia Regional Airport (COU)plane plane IND - COU
    6h 52m
    $180–563

West Lafayette to Jefferson City by bus and train (Amtrak)

Calendar7Weekly Services
Duration11h 6mAverage Duration
Ticket$144Cheapest Price
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Questions & Answers

Map of how to get from West Lafayette to Jefferson City.ExpandLaunch map view
  • Distance: 523.8 mi
  • Duration: 11h 6m

What companies run services between West Lafayette, IN, USA and Jefferson City, MO, USA?

You can take a bus from Lafayette Bus Stop to Jefferson City via Indianapolis Union Station, St Louis Bus Station, and Jefferson City in around 11h 33m. Alternatively, United Airlines flies from Purdue University Airport (LAF) to Columbia Regional Airport (COU) 3 times a day.

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