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How to get fromWest Lafayette to Lancasterby bus, plane, bus (Flixbus), train (Amtrak), car, shuttle, train, or bus (Greyhound)

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There are 6 ways to get from West Lafayette to Lancaster by bus, plane, bus (Flixbus), train (Amtrak), car, shuttle, train, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Chicago O'Hare International Airport, fly to Lancaster

    best
    1. Take the bus from Purdue Memorial Union to O'Hare Multi-Modal Facilitybus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Lancaster (LNS)plane plane ORD - LNS
    5h 49m
    $139–453

  2. Bus via Indianapolis (Greyhound)

    cheapest
    1. Take the bus from Lafayette Bus Stop to Indianapolis Union Stationbus bus Greyhound US0120S / ...
    2. Take the bus from Indianapolis Union Station to Harrisburg Bus Stationbus bus Greyhound US0421
    20h 2m
    $100–190

  3. Bus (Flixbus)

    1. Take the bus from Lafayette Bus Stop to Harrisburg Bus Stationbus bus FlixBus N2642 / ...
    16h 27m
    $109–182

  4. Train (Amtrak)

    1. Take the train from Lafayette Amtrak Station to 30th Street Stationtrain train Cardinal
    2. Take the train from 30th Street Station to Elizabethtown Amtrak Stationtrain train Keystone Service / ...
    27h 22m
    $322–669

  5. Drive 634 mi

    1. Drive from West Lafayette to Lancastercar car 634 mi
    11h 7m
    $116–168

  6. Shuttle to Indianapolis, fly to Philadelphia International Airport, train

    1. Take a shuttle bus from Purdue Mem Union - State Street to Indianapolis Airportshuttle bus
    2. Fly from Indianapolis (IND) to Philadelphia International Airport (PHL)plane plane IND - PHL
    3. Take the train from 30th Street Station to Elizabethtown Amtrak Stationtrain train
    9h 35m
    $165–946

West Lafayette to Lancaster by bus and train (Flixbus)

Calendar20Weekly Services
Duration16h 27mAverage Duration
Ticket$109Cheapest Price
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Questions & Answers

Map of how to get from West Lafayette to Lancaster.ExpandLaunch map view
  • Distance: 765.2 mi
  • Duration: 5h 49m

What companies run services between West Lafayette, IN, USA and Lancaster, PA, USA?

Flixbus USA operates a bus from Lafayette Bus Stop to Harrisburg Bus Station 3 times a day. Tickets cost $100–170 and the journey takes 13h 15m. Alternatively, you can take a train from Lafayette Amtrak Station to W. Chestnut & Water St. via 30th Street Station, Elizabethtown Amtrak Station, and AMTRAK ETown in around 27h 22m.

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