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How to get fromWest Lafayette to Missouriby bus, plane, train, bus (Greyhound), car, shuttle, or train (Amtrak)

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There are 9 ways to get from West Lafayette to Missouri by bus, plane, train, bus (Greyhound), car, shuttle, or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Chicago O'Hare International Airport, fly to Lambert–St. Louis International Airport

    best
    1. Take the bus from Purdue Memorial Union to O'Hare Multi-Modal Facilitybus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Lambert–St. Louis International Airport (STL)plane plane ORD - STL
    5h 29m
    $379–774

  2. Drive  487 mi

    cheapest
    1. Drive from West Lafayette to Kansas Citycar car 487 mi
    8h 15m
    $86–125

  3. Bus, train (Amtrak)

    1. Take the bus from Lafayette Amtrak Station to Chicago Union Stationbus bus Nashville
    2. Take the train from Chicago Union Station to Kansas Citytrain train Southwest Chief / ...
    10h 55m
    $264–414

  4. Bus (Greyhound)

    1. Take the bus from Lafayette Bus Stop to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis Union Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Kansas City Bus Stationbus bus
    11h 25m
    $102–157

  5. Shuttle to Indianapolis, fly to Kansas City

    1. Take a shuttle bus from Purdue Mem Union - State Street to Indianapolis Airportshuttle bus
    2. Fly from Indianapolis (IND) to Kansas City (MCI)plane plane IND - MCI
    5h 55m
    $125–733

  6. Bus to Chicago Midway International Airport, fly to Lambert–St. Louis International Airport

    1. Take the bus from Lafayette Bus Stop to Chicago Bus Stationbus bus
    2. Fly from Chicago Midway International Airport (MDW) to Lambert–St. Louis International Airport (STL)plane plane MDW - STL
    6h 12m
    $110–641

  7. Bus to Chicago Midway International Airport, fly to Kansas City

    1. Take the bus from Lafayette Bus Stop to Chicago Bus Stationbus bus
    2. Fly from Chicago Midway International Airport (MDW) to Kansas City (MCI)plane plane MDW - MCI
    7h 29m
    $132–788

  8. Bus, train via Naperville

    1. Take the bus from Lafayette Bus Stop to Chicago Bus Stationbus bus
    2. Take the train from Chicago Union Station to Napervilletrain train
    3. Take the train from Naperville Amtrak Station to Kansas Citytrain train
    11h 50m
    $245–389

  9. Train (Amtrak)

    1. Take the train from Lafayette Amtrak Station to Chicago Union Stationtrain train Cardinal
    2. Take the train from Chicago Union Station to Kansas Citytrain train Southwest Chief / ...
    11h 59m
    $307–472

West Lafayette to Missouri by bus, train, and tram (Amtrak)

Calendar14Weekly Services
Duration10h 55mAverage Duration
Ticket$264Cheapest Price
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Comparing Your Travel Options

Map of how to get from West Lafayette to Missouri.ExpandLaunch map view
  • Distance: 413.4 mi
  • Duration: 5h 29m

What companies run services between West Lafayette, IN, USA and Missouri, USA?

You can take a bus from Lafayette Bus Stop to Kansas City Bus Station via Indianapolis Union Station and St Louis Bus Station in around 11h 25m. Alternatively, you can take a train from Lafayette Amtrak Station to Metro Center via Chicago Union Station, Kansas City, and Union Station in around 11h 59m.

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