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How to get fromWest Lafayette to Muscatineby bus, taxi, train, car, or plane

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There are 10 ways to get from West Lafayette to Muscatine by bus, taxi, train, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, taxi

    best
    1. Take the bus from Lafayette Bus Stop to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to Davenportbus bus
    3. Take the taxi from Davenport to Muscatinetaxi taxi
    6h 55m
    $135–201

  2. Drive 267.9 mi

    cheapest
    1. Drive from West Lafayette to Muscatinecar car 267.9 mi
    5h 26m
    $49–71

  3. Train, drive (Amtrak)

    1. Take the train from Lafayette Amtrak Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain train
    3. Drive from Galesburg Amtrak Station to Muscatinecar car
    8h 44m
    $101–207

  4. Fly Purdue University Airport to Quad City International Airport, taxi

    1. Fly from Purdue University Airport (LAF) to Quad City International Airport (MLI)plane plane LAF - MLI
    2. Take the taxi from Moline-Airport-MLI to Muscatinetaxi taxi
    5h 51m
    $146–411

  5. Bus, taxi via Chicago

    1. Take the bus from Lafayette Amtrak Station to Chicago Union Stationbus bus
    2. Take the bus from Chicago Bus Station to Davenportbus bus
    3. Take the taxi from Davenport to Muscatinetaxi taxi
    7h 9m
    $140–209

  6. Bus, train, taxi

    1. Take the bus from Lafayette Bus Stop to Chicago Bus Stationbus bus
    2. Take the train from Chicago Union Station to Napervilletrain train
    3. Take the bus from Naperville to Molinebus bus
    4. Take the taxi from Moline to Muscatinetaxi taxi
    7h 46m

  7. Train, bus, taxi

    1. Take the train from Lafayette Amtrak Station to Chicago Union Stationtrain train
    2. Take the bus from Chicago Bus Station to Davenportbus bus
    3. Take the taxi from Davenport to Muscatinetaxi taxi
    8h 13m
    $155–244

  8. Bus to Chicago O'Hare International Airport, fly to Quad City International Airport, taxi

    1. Take the bus from Pmu to ORD Airportbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Quad City International Airport (MLI)plane plane ORD - MLI
    3. Take the taxi from Moline-Airport-MLI to Muscatinetaxi taxi
    5h 1m
    $191–451

  9. Bus to Chicago O'Hare International Airport, fly to Burlington Municipal Airport, drive

    1. Take the bus from Pmu to ORD Airportbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Burlington Municipal Airport (BRL)plane plane ORD - BRL
    3. Drive from Burlington Municipal Airport (BRL) to Muscatinecar car
    5h 36m
    $120–215

  10. Bus to Chicago O'Hare International Airport, fly to The Eastern Iowa Airport, taxi

    1. Take the bus from Pmu to ORD Airportbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to The Eastern Iowa Airport (CID)plane plane ORD - CID
    3. Take the taxi from Iowa City to Muscatinetaxi taxi
    6h 57m
    $226–501

Purdue University Airport (LAF) to Quad City International Airport (MLI) flights

Calendar20Weekly Planes
Duration5h 37mAverage Duration
Ticket$45Cheapest Price
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Questions & Answers

Map of how to get from West Lafayette to Muscatine.ExpandLaunch map view
  • Distance: 318.3 mi
  • Duration: 6h 55m

What companies run services between West Lafayette, IN, USA and Muscatine, IA, USA?

There is no direct connection from West Lafayette to Muscatine. However, you can take the bus to Chicago Bus Station, take the bus to Davenport, then take the taxi to Muscatine. Alternatively, you can take a train from Lafayette Amtrak Station to Muscatine via Chicago Union Station and Galesburg Amtrak Station in around 8h 44m.

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