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How to get fromWest Lafayette to Muscatineby bus, taxi, train, car, or plane

Find Transport to Muscatine

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There are 9 ways to get from West Lafayette to Muscatine by bus, taxi, train, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, taxi

    best
    1. Take the bus from Lafayette Bus Stop to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to Moline Center Stationbus bus
    3. Take the taxi from Moline Center Station to Muscatinetaxi taxi
    8h 18m
    $146–195

  2. Drive  267.9 mi

    cheapest
    1. Drive from West Lafayette to Muscatinecar car 267.9 mi
    5h 26m
    $49–71

  3. Train, drive (Amtrak)

    1. Take the train from Lafayette Amtrak Station to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain train
    3. Drive from Galesburg Amtrak Station to Muscatinecar car
    8h 44m
    $85–222

  4. Fly Purdue University Airport to Quad City International Airport, taxi

    1. Fly from Purdue University Airport (LAF) to Quad City International Airport (MLI)plane plane LAF - MLI
    2. Take the taxi from Moline-Airport-MLI to Muscatinetaxi taxi
    6h 58m
    $146–431

  5. Bus, taxi via Davenport

    1. Take the bus from Lafayette Amtrak Station to Chicago Union Stationbus bus
    2. Take the bus from Chicago Bus Station to Moline Center Stationbus bus
    3. Take the taxi from Miller Container to Muscatinetaxi taxi
    9h 32m
    $133–190

  6. Train, bus, taxi

    1. Take the train from Lafayette Amtrak Station to Chicago Union Stationtrain train
    2. Take the bus from Chicago Bus Station to Moline Center Stationbus bus
    3. Take the taxi from Miller Container to Muscatinetaxi taxi
    10h 36m
    $142–230

  7. Bus to Chicago O'Hare International Airport, fly to Quad City International Airport, taxi

    1. Take the bus from Purdue Memorial Union to O'Hare Multi-Modal Facilitybus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Quad City International Airport (MLI)plane plane ORD - MLI
    3. Take the taxi from Moline-Airport-MLI to Muscatinetaxi taxi
    5h 27m
    $186–441

  8. Bus to Chicago O'Hare International Airport, fly to The Eastern Iowa Airport, drive

    1. Take the bus from Purdue Memorial Union to O'Hare Multi-Modal Facilitybus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to The Eastern Iowa Airport (CID)plane plane ORD - CID
    3. Drive from Cedar-Rapids-Airport-CID to Muscatinecar car
    6h 3m
    $101–347

  9. Bus to Chicago O'Hare International Airport, fly to Burlington Municipal Airport, drive

    1. Take the bus from Purdue Memorial Union to O'Hare Multi-Modal Facilitybus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Burlington Municipal Airport (BRL)plane plane ORD - BRL
    3. Drive from Burlington Municipal Airport (BRL) to Muscatinecar car
    6h 4m
    $155–215

Purdue University Airport (LAF) to Quad City International Airport (MLI) flights

Calendar22Weekly Planes
Duration6h 29mAverage Duration
Ticket$46Cheapest Price
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Comparing Your Travel Options

Map of how to get from West Lafayette to Muscatine.ExpandLaunch map view
  • Distance: 327.5 mi
  • Duration: 8h 18m

What companies run services between West Lafayette, IN, USA and Muscatine, IA, USA?

There is no direct connection from West Lafayette to Muscatine. However, you can take the bus to Chicago Bus Station, take the bus to Moline Center Station, then take the taxi to Muscatine. Alternatively, you can take a train from Lafayette Amtrak Station to Muscatine via Chicago Union Station and Galesburg Amtrak Station in around 8h 44m.

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