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How to get fromWest Lafayette to Pittsburghby bus (Flixbus), train (Amtrak), car, plane, bus (Greyhound), shuttle, or bus

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There are 8 ways to get from West Lafayette to Pittsburgh by bus (Flixbus), train (Amtrak), car, plane, bus (Greyhound), shuttle, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus (Flixbus)

    best
    1. Take the bus from Lafayette Bus Stop to Pittsburgh Intermodal Stationbus bus FlixBus N2642 / ...
    8h 20m
    $60–95

  2. Train (Amtrak)

    1. Take the train from Lafayette Amtrak Station to Chicago Union Stationtrain train Cardinal
    2. Take the train from Chicago Union Station to Pittsburgh Amtrak Stationtrain train Floridian
    13h 49m
    $163–424

  3. Drive  418.3 mi

    1. Drive from West Lafayette to Pittsburghcar car 418.3 mi
    7h 17m
    $77–111

  4. Fly from Purdue University Airport

    1. Fly from Purdue University Airport (LAF) to Pittsburgh International Airport (PIT)plane plane LAF - PIT
    6h 29m
    $76–441

  5. Bus via Indianapolis (Greyhound)

    1. Take the bus from Lafayette Bus Stop to Indianapolis Union Stationbus bus Greyhound US0120S / ...
    2. Take the bus from Indianapolis Union Station to Pittsburgh Intermodal Stationbus bus Greyhound US0421
    11h 20m
    $65–111

  6. Shuttle to Indianapolis, fly

    1. Take a shuttle bus from Purdue Mem Union - State Street to Indianapolis Airportshuttle bus
    2. Fly from Indianapolis (IND) to Pittsburgh International Airport (PIT)plane plane IND - PIT
    7h 19m
    $455–1,033

  7. Bus to Chicago O'Hare International Airport, fly

    1. Take the bus from Purdue Memorial Union to O'Hare Multi-Modal Facilitybus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Pittsburgh International Airport (PIT)plane plane ORD - PIT
    6h 35m
    $436–1,271

  8. Bus to Chicago Midway International Airport, fly

    1. Take the bus from Lafayette Bus Stop to Chicago Bus Stationbus bus
    2. Fly from Chicago Midway International Airport (MDW) to Pittsburgh International Airport (PIT)plane plane MDW - PIT
    7h 8m
    $100–535

West Lafayette to Pittsburgh by bus (Flixbus)

Calendar10Weekly Buses
Duration8h 20mAverage Duration
Ticket$60Cheapest Price
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Comparing Your Travel Options

Map of how to get from West Lafayette to Pittsburgh.ExpandLaunch map view
  • Distance: 420.1 mi
  • Duration: 8h 20m

What companies run services between West Lafayette, IN, USA and Pittsburgh, PA, USA?

Flixbus USA operates a bus from Lafayette Bus Stop to Pittsburgh Intermodal Station once daily. Tickets cost $60–95 and the journey takes 8h 20m. Alternatively, you can take a train from Lafayette Amtrak Station to Pittsburgh Amtrak Station via Chicago Union Station in around 13h 49m.

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