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How to get fromWest Lafayette to Pittsburghby bus (Flixbus), train (Amtrak), car, plane, bus (Greyhound), shuttle, or bus

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There are 8 ways to get from West Lafayette to Pittsburgh by bus (Flixbus), train (Amtrak), car, plane, bus (Greyhound), shuttle, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Lafayette Bus Stop to Pittsburgh Intermodal Stationbus bus FlixBus N2642 / ...
    8h 20m
    $65–120

  2. Train (Amtrak)

    1. Take the train from Lafayette Amtrak Station to Chicago Union Stationtrain train Cardinal
    2. Take the train from Chicago Union Station to Pittsburgh Amtrak Stationtrain train Floridian
    13h 49m
    $189–399

  3. Drive 418.3 mi

    1. Drive from West Lafayette to Pittsburghcar car 418.3 mi
    7h 17m
    $77–111

  4. Fly from Purdue University Airport

    1. Fly from Purdue University Airport (LAF) to Pittsburgh International Airport (PIT)plane plane LAF - PIT
    7h
    $71–401

  5. Bus via Indianapolis

    1. Take the bus from Lafayette Bus Stop to Indianapolis Union Stationbus bus Greyhound US0100 / ...
    2. Take the bus from Indianapolis Union Station to Pittsburgh Intermodal Stationbus bus Greyhound US0421
    10h 15m
    $65–129

  6. Shuttle to Indianapolis, fly

    1. Take a shuttle bus from Purdue Mem Union - State Street to Indianapolis Airportshuttle bus
    2. Fly from Indianapolis (IND) to Pittsburgh International Airport (PIT)plane plane IND - PIT
    7h 19m
    $95–503

  7. Bus to Chicago O'Hare International Airport, fly

    1. Take the bus from Pmu to ORD Airportbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Pittsburgh International Airport (PIT)plane plane ORD - PIT
    6h 11m
    $436–1,271

  8. Bus to Chicago Midway International Airport, fly

    1. Take the bus from Lafayette Bus Stop to Chicagobus bus
    2. Fly from Chicago Midway International Airport (MDW) to Pittsburgh International Airport (PIT)plane plane MDW - PIT
    6h 52m
    $97–504

West Lafayette to Pittsburgh by bus

Calendar17Weekly Buses
Duration8h 20mAverage Duration
Ticket$65Cheapest Price
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Questions & Answers

Map of how to get from West Lafayette to Pittsburgh.ExpandLaunch map view
  • Distance: 420.1 mi
  • Duration: 8h 20m

What companies run services between West Lafayette, IN, USA and Pittsburgh, PA, USA?

Flixbus USA operates a bus from Lafayette Bus Stop to Pittsburgh Intermodal Station once daily. Tickets cost $65–120 and the journey takes 8h 20m. FlixBus-us also services this route once daily. Alternatively, you can take a train from Lafayette Amtrak Station to Pittsburgh Amtrak Station via Chicago Union Station in around 13h 49m.

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