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How to get fromWest Melbourne to Key Westby car, plane, bus, train, shuttle, or bus (Greyhound)

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There are 8 ways to get from West Melbourne to Key West by car, plane, bus, train, shuttle, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Orlando Sanford, fly

    best
    1. Drive from West Melbourne to Orlando-Sanford-Airport-SFBcar car
    2. Fly from Orlando Sanford (SFB) to Key West International Airport (EYW)plane plane SFB - EYW
    2h 55m
    $58–271

  2. Drive  330.9 mi

    cheapest
    1. Drive from West Melbourne to Key Westcar car 330.9 mi
    6h 21m
    $57–82

  3. Bus, train

    1. Take the bus from Sebastian to Fort Piercebus bus
    2. Take the bus from Fort Pierce to West Palm Beach, FLbus bus
    3. Take the train from West Palm Beach Station to Miami Airport Stationtrain train
    4. Take the bus from Miami Airport Station to Big Pine Keybus bus
    5. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    12h 13m
    $128–176

  4. Fly from Melbourne International Airport

    1. Fly from Melbourne International Airport (MLB) to Key West International Airport (EYW)plane plane MLB - EYW
    6h 3m
    $82–354

  5. Line 20 bus, shuttle to Orlando, fly

    1. Take the bus from West New Haven/ E Laila Dr NE Corner to West New Haven Ave @ Goodwillbus bus
    2. Take a shuttle bus from Melbourne, FL - Mobil Gas to Orlando Airportshuttle bus
    3. Fly from Orlando (MCO) to Key West International Airport (EYW)plane plane MCO - EYW
    5h 3m
    $132–780

  6. Drive, train, bus

    1. Drive from West Melbourne to Orlandocar car
    2. Take the train from Orlando to Miamitrain train
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    4. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    12h 15m
    $78–226

  7. Bus

    1. Take the bus from Sebastian to Miami Airport Stationbus bus
    2. Take the bus from Miami Airport Station to Big Pine Keybus bus
    3. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    12h 42m
    $138–187

  8. Shuttle, bus

    1. Take a shuttle bus from Melbourne, FL - Mobil Gas to Orlando Airportshuttle bus
    2. Take the bus from Orlando - RedCoach Station, FL to Miami Airportbus bus
    3. Take a shuttle bus from Miami, FL - International Airport to Key West, FLshuttle bus
    14h 30m
    $286–352

West Melbourne to Key West by bus and shuttle

Calendar21Weekly Services
Duration14h 30mAverage Duration
Ticket$286Cheapest Price
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Comparing Your Travel Options

Map of how to get from West Melbourne to Key West.ExpandLaunch map view
  • Distance: 367.9 mi
  • Duration: 2h 55m

What companies run services between West Melbourne, FL, USA and Key West, FL, USA?

Delta and American Airlines fly from Melbourne International Airport (MLB) to Key West International Airport (EYW) 5 times a day. Alternatively, you can take a vehicle from West Melbourne to N Roosevelt & 3rd Street via Sebastian, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 12h 42m.

Airlines
Train operators
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