There are 8 ways to get from West Melbourne to Key West by car, plane, bus (Greyhound), shuttle, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Drive to Orlando Sanford, fly
best- Drive from West Melbourne to Orlando-Sanford-Airport-SFBcar
- Fly from Orlando Sanford (SFB) to Key West International Airport (EYW)plane SFB - EYW
2h 52m$59–282Bus via Fort Pierce South
- Take the bus from Sebastian to Fort Piercebus
- Take the bus from Fort Pierce to Miami Airportbus
- Take the bus from Miami Airport Station to Big Pine Keybus
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus Lks
11h 23m$139–212Drive 330.9 mi
- Drive from West Melbourne to Key Westcar 330.9 mi
6h 21m$61–88Shuttle, bus
- Take a shuttle bus from Melbourne, FL - Mobil Gas to Orlando Airport
- Take the bus from Orlando to Fort Lauderdale International Airportbus
- Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key West, FL
14h 14m$270–348Line 20 bus, shuttle to Orlando, fly
- Take the bus from West New Haven/ E Laila Dr NE Corner to West New Haven Ave @ Goodwillbus
- Take a shuttle bus from Melbourne, FL - Mobil Gas to Orlando Airport
- Fly from Orlando (MCO) to Key West International Airport (EYW)plane MCO - EYW
4h 55m$132–730Fly from Melbourne International Airport
- Fly from Melbourne International Airport (MLB) to Key West International Airport (EYW)plane MLB - EYW
6h 5m$98–404Drive, train, bus
- Drive from West Melbourne to Orlandocar
- Take the train from Orlando to Miamitrain
- Take the bus from Miami Airport Station to Big Pine Keybus
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus Lks
12h 13m$75–232Bus
- Take the bus from Sebastian to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Big Pine Keybus
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus Lks
12h 42m$132–192
West Melbourne to Key West by bus, shuttle, and foot
Questions & Answers
The cheapest way to get from West Melbourne to Key West is to drive which costs $60 - $90 and takes 6h 21m.
The fastest way to get from West Melbourne to Key West is to drive and fly which takes 2h 52m and costs $55 - $290.
No, there is no direct bus from West Melbourne to Key West. However, there are services departing from Sebastian and arriving at N Roosevelt & 3rd Street via Fort Pierce, Miami Airport Station and Big Pine Key - CVS / MM30. The journey, including transfers, takes approximately 11h 23m.
The distance between West Melbourne and Key West is 370 miles. The road distance is 332.8 miles.
The best way to get from West Melbourne to Key West without a car is to bus via Fort Pierce South which takes 11h 23m and costs $130 - $220.
It takes approximately 2h 52m to get from West Melbourne to Key West, including transfers.
West Melbourne to Key West bus services, operated by Greyhound USA, depart from Sebastian station.
The best way to get from West Melbourne to Key West is to bus via Fort Pierce South which takes 11h 23m and costs $130 - $220. Alternatively, you can fly, which costs $95 - $410 and takes 6h 5m.
West Melbourne to Key West bus services, operated by Greyhound USA, arrive at Fort Pierce station.
Yes, the driving distance between West Melbourne to Key West is 333 miles. It takes approximately 6h 21m to drive from West Melbourne to Key West.
What companies run services between West Melbourne, FL, USA and Key West, FL, USA?
You can take a vehicle from West Melbourne to N Roosevelt & 3rd Street via Sebastian, Fort Pierce, Miami Airport, Miami International Airport, Miami, Airport Intermodal Station, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 11h 23m. Alternatively, Delta and American Airlines fly from Melbourne International Airport (MLB) to Key West International Airport (EYW) 4 times a day.
- Website
- aa.com
Flights from Orlando to Key West International Airport via Miami
- Ave. Duration
- 3h 10m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $35–230
Flights from Melbourne International Airport to Key West International Airport via Charlotte
- Ave. Duration
- 6h 45m
- When
- Every day
- Estimated price
- $90–410
- Website
- delta.com
Flights from Melbourne International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 5h 19m
- When
- Every day
- Estimated price
- $85–390
- Website
- allegiantair.com
Flights from Orlando Sanford to Key West International Airport
- Ave. Duration
- 1h 18m
- When
- Thursday, Sunday, Monday, and Friday
- Estimated price
- $35–250
- Website
- flybreeze.com
Flights from Orlando to Key West International Airport
- Ave. Duration
- 1h 15m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $65–650
- Phone
- +1 831-539-2901
- [email protected]
- Website
- gobrightline.com
Train from Orlando to Miami
- Ave. Duration
- 3h 34m
- Frequency
- Every 2 hours
- Estimated price
- $40–170
- Book at
- https://www.gobrightline.com
- Smart
- $40–90
- Premium
- $110–170
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Sebastian to Fort Pierce
- Ave. Duration
- 40 min
- Frequency
- Once daily
- Estimated price
- $4–10
- Website
- https://www.greyhound.com/
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a day
- Estimated price
- $20–40
- Website
- https://www.greyhound.com/
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a day
- Estimated price
- $20–40
- Website
- https://www.greyhound.com/
Bus from Sebastian to Miami Airport Station
- Ave. Duration
- 5h 20m
- Frequency
- Once daily
- Estimated price
- $27–50
- Website
- https://www.greyhound.com/
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a day
- Estimated price
- $20–40
- Website
- https://www.greyhound.com/
- Phone
- +1 877 733 0724
- Website
- redcoachusa.com
Bus from Fort Pierce to Miami Airport
- Ave. Duration
- 2h 15m
- Frequency
- 3 times a day
- Estimated price
- $30–60
- Website
- https://www.redcoachusa.com
- Phone
- +1 305-809-3700
- Website
- cityofkeywest-fl.gov
Bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Street
- Ave. Duration
- 1h 9m
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- https://www.cityofkeywest-fl.gov/595/Schedules-and-Route-Maps
Bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Street
- Ave. Duration
- 1h 9m
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- https://www.cityofkeywest-fl.gov/595/Schedules-and-Route-Maps
Bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Street
- Ave. Duration
- 1h 9m
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- https://www.cityofkeywest-fl.gov/595/Schedules-and-Route-Maps
- Phone
- +1 772-343-0217
- Website
- smartshuttleline.com
Shuttle from Melbourne, FL - Mobil Gas to Orlando Airport
- Ave. Duration
- 56 min
- Frequency
- 4 times a day
- Estimated price
- $55–65
- Schedules at
- smartshuttleline.com
- one passenger
- $55–65
Shuttle from Melbourne, FL - Mobil Gas to Orlando Airport
- Ave. Duration
- 56 min
- Frequency
- 4 times a day
- Estimated price
- $55–65
- Schedules at
- smartshuttleline.com
- one passenger
- $55–65
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Orlando to Fort Lauderdale International Airport
- Ave. Duration
- 3h 20m
- Frequency
- Twice daily
- Estimated price
- $30–55
- Schedules at
- flixbus.com
- Phone
- +1 (305) 289-9997
- [email protected]
- Website
- keysshuttle.com
Shuttle from Fort Lauderdale, FL - International Airport to Key West, FL
- Ave. Duration
- 4h 30m
- Frequency
- 3 times a day
- Estimated price
- $180–220
- Website
- https://www.keysshuttle.com
- Phone
- +1 321-633-1878
- Website
- 321transit.com
Bus from West New Haven/ E Laila Dr NE Corner to West New Haven Ave @ Goodwill
- Ave. Duration
- 39 min
- Frequency
- Every 2 hours
- Estimated price
- $2
- Website
- https://321transit.com/
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