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How to get fromWest Melbourne to Key Westby bus, shuttle, plane, bus (Greyhound), car, or train

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There are 8 ways to get from West Melbourne to Key West by bus, shuttle, plane, bus (Greyhound), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Line 20 bus, shuttle to Orlando, fly

    best
    1. Take the bus from West New Haven/ E Laila Dr NE Corner to West New Haven Ave @ Goodwillbus bus
    2. Take a shuttle bus from Melbourne, FL - Mobil Gas to Orlando Airportshuttle bus
    3. Fly from Orlando (MCO) to Key West International Airport (EYW)plane plane MCO - EYW
    5h 3m
    $132–730

  2. Drive to Orlando Sanford, fly

    cheapest
    1. Drive from West Melbourne to Orlando-Sanford-Airport-SFBcar car
    2. Fly from Orlando Sanford (SFB) to Key West International Airport (EYW)plane plane SFB - EYW
    2h 55m
    $59–272

  3. Bus via Fort Pierce South

    1. Take the bus from Sebastian to Fort Piercebus bus
    2. Take the bus from Fort Pierce to Miami Airportbus bus
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    4. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    11h 23m
    $136–206

  4. Drive 330.9 mi

    1. Drive from West Melbourne to Key Westcar car 330.9 mi
    6h 21m
    $61–88

  5. Shuttle, bus

    1. Take a shuttle bus from Melbourne, FL - Mobil Gas to Orlando Airportshuttle bus
    2. Take the bus from Orlando to Fort Lauderdale International Airportbus bus
    3. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key West, FLshuttle bus
    14h 14m
    $268–342

  6. Fly from Melbourne International Airport

    1. Fly from Melbourne International Airport (MLB) to Key West International Airport (EYW)plane plane MLB - EYW
    6h 2m
    $88–384

  7. Drive, train, bus

    1. Drive from West Melbourne to Orlandocar car
    2. Take the train from Orlando to Miamitrain train
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    4. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    12h 15m
    $72–227

  8. Bus

    1. Take the bus from Sebastian to Miami Airport Stationbus bus
    2. Take the bus from Miami Airport Station to Big Pine Keybus bus
    3. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus bus Lks
    12h 42m
    $125–182

West Melbourne to Key West by bus, shuttle, and foot

Calendar14Weekly Services
Duration14h 14mAverage Duration
Ticket$268Cheapest Price
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Questions & Answers

Map of how to get from West Melbourne to Key West.ExpandLaunch map view
  • Distance: 347.3 mi
  • Duration: 5h 3m

What companies run services between West Melbourne, FL, USA and Key West, FL, USA?

You can take a vehicle from West Melbourne to N Roosevelt & 3rd Street via Sebastian, Fort Pierce, Miami Airport, Miami International Airport, Miami, Airport Intermodal Station, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 11h 23m. Alternatively, Delta and American Airlines fly from Melbourne International Airport (MLB) to Key West International Airport (EYW) 5 times a day.

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