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How to get fromWest Palm Beach to Des Moinesby plane, bus (Flixbus, Greyhound), train, bus, or car

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There are 6 ways to get from West Palm Beach to Des Moines by plane, bus (Flixbus, Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from President Donald J. Trump International Airport

    best
    1. Fly from President Donald J. Trump International Airport (PBI) to Des Moines (DSM)plane plane PBI - DSM
    5h 26m
    $236–976

  2. Train to Miami International Airport, fly

    cheapest
    1. Take the train from West Palm Beach Station to Miami Airport Stationtrain train
    2. Fly from Miami International Airport (MIA) to Des Moines (DSM)plane plane MIA - DSM
    6h 42m
    $202–832

  3. Bus

    1. Take the bus from West Palm Beach Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    3. Take the bus from St Louis Bus Station to Des Moinesbus bus
    33h 20m
    $243–452

  4. Train, bus

    1. Take the train from West Palm Beach Amtrak Station to Chicago Union Stationtrain train Floridian
    2. Take the bus from Chicago Bus Station to Des Moinesbus bus Greyhound US0123S / ...
    2d 4h
    $692–1,408

  5. Drive 1,478.4 mi

    1. Drive from West Palm Beach to Des Moinescar car 1,478.4 mi
    25h 27m
    $270–390

  6. Train to Fort Lauderdale–Hollywood International Airport, fly

    1. Take the train from West Palm Beach to Fort Lauderdaletrain train
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Des Moines (DSM)plane plane FLL - DSM
    5h 58m
    $229–927

West Palm Beach to Des Moines by bus

Calendar7Weekly Buses
Duration33h 20mAverage Duration
Ticket$243Cheapest Price
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Questions & Answers

Map of how to get from West Palm Beach to Des Moines.ExpandLaunch map view
  • Distance: 1,288.9 mi
  • Duration: 5h 26m

What companies run services between West Palm Beach, FL, USA and Des Moines, IA, USA?

Delta, American Airlines, and United Airlines fly from President Donald J. Trump International Airport (PBI) to Des Moines (DSM) every 3 hours. Alternatively, you can take a bus from West Palm Beach Bus Station to Des Moines via Atlanta Bus Station and St Louis Bus Station in around 33h 20m.

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