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How to get fromWest Palm Beach to Mayo Clinic Floridaby train, plane, taxi, train (Amtrak), bus (Flixbus, Greyhound), car, or bus (Flixbus)

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There are 6 ways to get from West Palm Beach to Mayo Clinic Florida by train, plane, taxi, train (Amtrak), bus (Flixbus, Greyhound), car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Fort Lauderdale–Hollywood International Airport, fly, taxi

    best
    1. Take the train from West Palm Beach to Fort Lauderdaletrain train
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Jacksonville (JAX)plane plane FLL - JAX
    3. Take the taxi from Jacksonville-Airport-JAX to Mayo Clinic Floridataxi taxi
    4h 17m
    $212–796

  2. Drive 276.5 mi

    cheapest
    1. Drive from West Palm Beach to Mayo Clinic Floridacar car 276.5 mi
    4h 34m
    $51–73

  3. Train (Amtrak)

    1. Take the train from West Palm Beach Amtrak Station to Jacksonvilletrain train Silver Meteor / ...
    7h 42m
    $162–294

  4. Bus

    1. Take the bus from West Palm Beach Bus Station to Jacksonvillebus bus FlixBus 2431
    8h 4m
    $55–102

  5. Train to Miami International Airport, fly, taxi

    1. Take the train from West Palm Beach Station to Miami Airport Stationtrain train
    2. Fly from Miami International Airport (MIA) to Jacksonville (JAX)plane plane MIA - JAX
    3. Take the taxi from Jacksonville-Airport-JAX to Mayo Clinic Floridataxi taxi
    4h 52m
    $125–431

  6. Bus via Daytona Beach (Flixbus)

    1. Take the bus from West Palm Beach Bus Station to Daytona Beachbus bus FlixBus 2431
    2. Take the bus from Daytona Beach to Jacksonvillebus bus FlixBus 2433 / ...
    8h 40m
    $55–89

Fort Lauderdale–Hollywood International Airport (FLL) to Jacksonville (JAX) flights

Calendar21Weekly Planes
Duration1h 22mAverage Duration
Ticket$55Cheapest Price
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Questions & Answers

Map of how to get from West Palm Beach to Mayo Clinic Florida.ExpandLaunch map view
  • Distance: 393.8 mi
  • Duration: 4h 17m

What companies run services between West Palm Beach, FL, USA and Mayo Clinic Florida, FL, USA?

Amtrak operates a train from West Palm Beach Amtrak Station to Jacksonville twice daily. Tickets cost $100–230 and the journey takes 7h 9m. Alternatively, Flixbus USA operates a bus from West Palm Beach Bus Station to Jacksonville once daily. Tickets cost $45–80 and the journey takes 6h 45m. Greyhound USA also services this route once daily.

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