Rome2Rio

How to get fromWest Palm Beach to Santeeby plane, car, bus (Flixbus, Greyhound), or train

Find Transport to Santee

See all options

There are 5 ways to get from West Palm Beach to Santee by plane, car, bus (Flixbus, Greyhound), or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Charleston International Airport, drive

    best
    1. Fly from President Donald J. Trump International Airport (PBI) to Charleston International Airport (CHS)plane plane PBI - CHS
    2. Drive from Charleston-Airport-CHS to Santeecar car
    2h 43m
    $124–751

  2. Drive 519.4 mi

    cheapest
    1. Drive from West Palm Beach to Santeecar car 519.4 mi
    8h 31m
    $95–137

  3. Bus

    1. Take the bus from West Palm Beach Bus Station to Orlando Bus Stationbus bus FlixBus N2401 / ...
    2. Take the bus from Orlando Bus Station to Orangeburgbus bus FlixBus 2433
    12h 8m
    $166–249

  4. Train, drive (Amtrak)

    1. Take the train from West Palm Beach Amtrak Station to Charleston Amtrak Stationtrain train Silver Meteor
    2. Drive from Charleston Amtrak Station to Santeecar car
    12h 44m
    $197–407

  5. Fly to Columbia, drive

    1. Fly from President Donald J. Trump International Airport (PBI) to Columbia (CAE)plane plane PBI - CAE
    2. Drive from Columbia-Airport-CAE to Santeecar car
    4h 53m
    $223–1,107

President Donald J. Trump International Airport (PBI) to Charleston International Airport (CHS) flights

Calendar27Weekly Planes
Duration3h 36mAverage Duration
Ticket$94Cheapest Price
See schedules

Questions & Answers

Map of how to get from West Palm Beach to Santee.ExpandLaunch map view
  • Distance: 487.5 mi
  • Duration: 2h 43m

What companies run services between West Palm Beach, FL, USA and Santee, SC, USA?

You can take a bus from West Palm Beach Bus Station to Santee via Orlando Bus Station and Orangeburg in around 12h 8m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound