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How to get fromWest Plains to Knoxvilleby car, plane, taxi, or shuttle

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There are 7 ways to get from West Plains to Knoxville by car, plane, taxi, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive 514.4 mi

    best
    1. Drive from West Plains to Knoxvillecar car 514.4 mi
    9h 30m
    $94–136

  2. Drive to Bill And Hillary Clinton National Airport, fly to Mcghee Tyson Airport

    1. Drive from West Plains to Bill And Hillary Clinton National Airport (LIT)car car
    2. Fly from Bill And Hillary Clinton National Airport (LIT) to Mcghee Tyson Airport (TYS)plane plane LIT - TYS
    6h 50m
    $248–1,067

  3. Taxi, shuttle to Springfield-Branson National Airport, fly to Mcghee Tyson Airport

    1. Take the taxi from West Plains to Mountain Grovetaxi taxi
    2. Take a shuttle bus from Mountain Grove to Springfieldshuttle bus
    3. Fly from Springfield-Branson National Airport (SGF) to Mcghee Tyson Airport (TYS)plane plane SGF - TYS
    7h 23m
    $282–888

  4. Drive to Jonesboro Municipal Airport, fly to Nashville, drive

    1. Drive from West Plains to Jonesboro Municipal Airport (JBR)car car
    2. Fly from Jonesboro Municipal Airport (JBR) to Nashville (BNA)plane plane JBR - BNA
    3. Drive from Nashville-Airport-BNA to Knoxvillecar car
    6h 38m
    $180–499

  5. Drive to Waynesville-St. Robert Regional Airport, fly to Nashville, drive

    1. Drive from West Plains to Waynesville-St. Robert Regional Airport (TBN)car car
    2. Fly from Waynesville-St. Robert Regional Airport (TBN) to Nashville (BNA)plane plane TBN - BNA
    3. Drive from Nashville-Airport-BNA to Knoxvillecar car
    6h 9m
    $131–623

  6. Drive to Waynesville-St. Robert Regional Airport, fly to Mcghee Tyson Airport

    1. Drive from West Plains to Waynesville-St. Robert Regional Airport (TBN)car car
    2. Fly from Waynesville-St. Robert Regional Airport (TBN) to Mcghee Tyson Airport (TYS)plane plane TBN - TYS
    6h 41m
    $261–993

  7. Drive to Jonesboro Municipal Airport, fly to Mcghee Tyson Airport

    1. Drive from West Plains to Jonesboro Municipal Airport (JBR)car car
    2. Fly from Jonesboro Municipal Airport (JBR) to Mcghee Tyson Airport (TYS)plane plane JBR - TYS
    5h 57m
    $345–849

Bill And Hillary Clinton National Airport (LIT) to Mcghee Tyson Airport (TYS) flights

Calendar43Weekly Planes
Duration4h 33mAverage Duration
Ticket$164Cheapest Price
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Questions & Answers

Map of how to get from West Plains to Knoxville.ExpandLaunch map view
  • Distance: 514.4 mi
  • Duration: 9h 30m

What companies run services between West Plains, MO, USA and Knoxville, TN, USA?

You can drive from West Plains to Knoxville in around 9h 30m.

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