There are 4 ways to get from Wetzlar to Karlovy Vary by bus, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Wetzlar to Jena bus stationbus
- Take the bus from Jena bus station to Chemnitz central bus stationbus N69 / ...
- Take the bus from Chemnitz central bus station to Karlovy Varybus 910
8h 25mKč 988–1,472Train
- Take the train from Gießen Bahnhof to Frankfurttrain
- Take the train from Frankfurt to Nürnberg Hbftrain 41 / ...
- Take the train from Nürnberg Hbf to Chebtrain
- Take the train from Cheb to Karlovy Varytrain Re / ...
8h 29mKč 1,584–3,167Drive 395.9 km
- Drive from Wetzlar to Karlovy Varycar 395.9 km
4h 15mKč 1,790–2,585Train, bus
- Take the train from Gießen Bahnhof to Frankfurttrain Re30
- Take the bus from Frankfurt central train station to Karlovy Varybus 068
10h 45mKč 1,030–1,808
Wetzlar to Karlovy Vary by bus
Comparing Your Travel Options
The cheapest way to get from Wetzlar to Karlovy Vary is to bus which costs 950 Kč - 1 500 Kč and takes 8h 25m.
The fastest way to get from Wetzlar to Karlovy Vary is to drive which takes 4h 15m and costs 1 700 Kč - 2 600 Kč.
No, there is no direct bus from Wetzlar to Karlovy Vary. However, there are services departing from Wetzlar and arriving at Karlovy Vary via Jena bus station and Chemnitz central bus station. The journey, including transfers, takes approximately 8h 25m.
No, there is no direct train from Wetzlar to Karlovy Vary. However, there are services departing from Wetzlar Bahnhof and arriving at Karlovy Vary via Gießen Bahnhof, Frankfurt, Nürnberg Hbf and Cheb. The journey, including transfers, takes approximately 8h 29m.
The distance between Wetzlar and Karlovy Vary is 457 km. The road distance is 395.9 km.
The best way to get from Wetzlar to Karlovy Vary without a car is to bus which takes 8h 25m and costs 950 Kč - 1 500 Kč.
It takes approximately 8h 25m to get from Wetzlar to Karlovy Vary, including transfers.
Wetzlar to Karlovy Vary bus services, operated by FlixBus, depart from Wetzlar station.
Wetzlar to Karlovy Vary train services, operated by Deutsche Bahn Regio (DB Regional), depart from Gießen Bahnhof station.
The best way to get from Wetzlar to Karlovy Vary is to bus which takes 8h 25m and costs 950 Kč - 1 500 Kč. Alternatively, you can train, which costs 1 500 Kč - 3 200 Kč and takes 8h 29m.
What companies run services between Wetzlar, Germany and Karlovy Vary, Czechia?
You can take a bus from Wetzlar to Karlovy Vary via Jena bus station and Chemnitz central bus station in around 8h 25m. Alternatively, you can take a train from Wetzlar Bahnhof to Karlovy Vary via Gießen Bahnhof, Frankfurt, Nürnberg Hbf, and Cheb in around 8h 29m.
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Gießen Bahnhof to Frankfurt
- Ave. Duration
- 58 min
- Frequency
- Every 2 hours
- Estimated price
- Kč 180–250
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Nürnberg Hbf to Cheb
- Ave. Duration
- 1h 44m
- Frequency
- Every 4 hours
- Estimated price
- Kč 410–600
- Website
- Deutsche Bahn Regio (DB Regional)
Train from Gießen Bahnhof to Frankfurt
- Ave. Duration
- 58 min
- Frequency
- Every 2 hours
- Estimated price
- Kč 180–250
- Website
- Deutsche Bahn Regio (DB Regional)
- Phone
- +49 30 2970
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Gießen Bahnhof to Frankfurt
- Ave. Duration
- 44 min
- Frequency
- Once daily
- Estimated price
- Kč 250–550
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Frankfurt to Nürnberg Hbf
- Ave. Duration
- 2h 1m
- Frequency
- Hourly
- Estimated price
- Kč 850–1,800
- Website
- Deutsche Bahn Intercity (DB IC)
Train from Gießen Bahnhof to Frankfurt
- Ave. Duration
- 44 min
- Frequency
- Once daily
- Estimated price
- Kč 250–550
- Website
- Deutsche Bahn Intercity (DB IC)
- Phone
- +420 221 111 122
- [email protected]
- Website
- Czech Railways (ČD)
Train from Cheb to Karlovy Vary
- Ave. Duration
- 49 min
- Frequency
- Hourly
- Estimated price
- Kč 110–170
- Website
- Czech Railways (ČD)
- Phone
- +49 30 300 137 300
- [email protected]
- Website
- Flixbus
Bus from Wetzlar to Jena bus station
- Ave. Duration
- 3h 5m
- Frequency
- Once daily
- Estimated price
- Kč 550–850
- Website
- Flixbus
Bus from Jena bus station to Chemnitz central bus station
- Ave. Duration
- 1h 25m
- Frequency
- Every 4 hours
- Estimated price
- Kč 230–350
- Website
- Flixbus
Bus from Chemnitz central bus station to Karlovy Vary
- Ave. Duration
- 1h 55m
- Frequency
- Twice daily
- Estimated price
- Kč 190–290
- Website
- Flixbus
Bus from Frankfurt central train station to Karlovy Vary
- Ave. Duration
- 6h 55m
- Frequency
- Once daily
- Estimated price
- Kč 850–1,300
- Website
- Flixbus
Want to know more about travelling around Czechia
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Booking & Getting There
Wetzlar to Karlovy Vary bus services, operated by FlixBus, arrive at Jena bus station.
Wetzlar to Karlovy Vary train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Frankfurt station.
Yes, the driving distance between Wetzlar to Karlovy Vary is 396 km. It takes approximately 4h 15m to drive from Wetzlar to Karlovy Vary.
Book your Wetzlar to Karlovy Vary train tickets online with Omio.
Book your Wetzlar to Karlovy Vary bus tickets online with Omio and FlixBus.
There are 1494+ hotels available in Karlovy Vary.

















