Rome2Rio

How to get fromWheeling to Louisvilleby plane, train, bus, car, or bus (Amtrak)

Find Transport to Louisville

See all options

There are 7 ways to get from Wheeling to Louisville by plane, train, bus, car, or bus (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Chicago O'Hare International Airport to Louisville International Airport

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Louisville International Airport (SDF)plane plane ORD - SDF
    4h 13m
    $70–427

  2. Train, bus via Chicago

    cheapest
    1. Take the train from Wheeling to Chicago Union Stationtrain train Ncs
    2. Take the bus from Chicago Bus Station to Indianapolis Union Stationbus bus
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    8h 34m
    $54–106

  3. Train, bus

    1. Take the train from Wheeling to Chicago Union Stationtrain train Ncs
    2. Take the train from Chicago Union Station to Indianapolistrain train
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    10h 14m
    $87–181

  4. Drive 318.3 mi

    1. Drive from Wheeling to Louisvillecar car 318.3 mi
    5h 38m
    $59–84

  5. Fly Chicago O'Hare International Airport to Blue Grass Airport, drive

    1. Fly from Chicago O'Hare International Airport (ORD) to Blue Grass Airport (LEX)plane plane ORD - LEX
    2. Drive from Lexington-Airport-LEX to Louisvillecar car
    4h 22m
    $117–673

  6. Train to Chicago Midway International Airport, fly to Louisville International Airport

    1. Take the train from Wheeling to Chicago Union Stationtrain train
    2. Fly from Chicago Midway International Airport (MDW) to Louisville International Airport (SDF)plane plane MDW - SDF
    5h 17m
    $88–564

  7. Bus (Amtrak)

    1. Take the bus from Chicago Union Station to Louisville, KYbus bus Chicago
    10h 7m
    $56–67

Wheeling to Louisville by train, foot, and bus

Calendar14Weekly Services
Duration8h 34mAverage Duration
Ticket$54Cheapest Price
See schedules

Questions & Answers

Map of how to get from Wheeling to Louisville.ExpandLaunch map view
  • Distance: 305.2 mi
  • Duration: 4h 13m

What companies run services between Wheeling, IL, USA and Louisville, KY, USA?

American Airlines and United Airlines fly from Chicago O'Hare International Airport (ORD) to Louisville International Airport (SDF) every 3 hours. Alternatively, Amtrak Thruway operates a bus from Chicago Union Station to Louisville, KY twice daily. Tickets cost $50–60 and the journey takes 7h.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers